4X3G

Crystal structure of SIAH1 SINA domain in complex with a USP19 peptide

Summary for 4X3G

Related4C9Z
DescriptorE3 ubiquitin-protein ligase SIAH1, Ubiquitin carboxyl-terminal hydrolase 19, ZINC ION, ... (4 entities in total)
Functional Keywordsligase, ubiquitin-protein ligase, hydrolase, ubiquitin specific protease, protein-peptide complex, sgc
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm Q8IUQ4
Endoplasmic reticulum membrane ; Single-pass membrane protein  O94966
Total number of polymer chains4
Total molecular weight46586.8
Authors
Walker, J.R.,Dong, A.,Zhang, Q.,Huang, X.,Li, Y.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Tong, Y.,Structural Genomics Consortium (SGC) (deposition date: 2014-11-28, release date: 2014-12-31, Last modification date: 2018-01-24)
Primary citation
Walker, J.R.,Dong, A.,Zhang, Q.,Huang, X.,Li, Y.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Tong, Y.,Structural Genomics Consortium (SGC)
Crystal structure of SIAH1 SINA domain in complex with a USP19 peptide
To be published,
Experimental method
X-RAY DIFFRACTION (2.34 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.27430 2.4% 2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171588
PDB entries from 2020-11-25