4ASH
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![BU of 4ash by Molmil](/molmil-images/mine/4ash) | |
3UQS
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3SFG
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4NRU
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![BU of 4nru by Molmil](/molmil-images/mine/4nru) | Murine Norovirus RNA-dependent-RNA-polymerase in complex with Compound 6, a suramin derivative | 分子名称: | 4-({4-methyl-3-[(3-nitrobenzoyl)amino]benzoyl}amino)naphthalene-1,5-disulfonic acid, MAGNESIUM ION, RNA dependent RNA polymerase | 著者 | Milani, M, Croci, R, Pezzullo, M, Tarantino, D, Mastrangelo, E, Bolognesi, M. | 登録日 | 2013-11-27 | 公開日 | 2014-10-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds. Plos One, 9, 2014
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4X2V
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8A8X
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![BU of 8a8x by Molmil](/molmil-images/mine/8a8x) | TRIM7 PRYSPRY in complex with a MNV1-NS3 peptide HDDFGLQ | 分子名称: | E3 ubiquitin-protein ligase TRIM7, MNV1-NS3 C term peptide | 著者 | Luptak, J. | 登録日 | 2022-06-24 | 公開日 | 2022-07-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing. Viruses, 14, 2022
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4O4R
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![BU of 4o4r by Molmil](/molmil-images/mine/4o4r) | Murine Norovirus RdRp in complex with PPNDS | 分子名称: | 3-[(E)-{4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]pyridin-2-yl}diazenyl]-7-nitronaphthalene-1,5-disulfonic acid, RNA-dependent-RNA-polymerase, SULFATE ION | 著者 | Croci, R, Tarantino, D, Milani, M, Pezzullo, M, Bolognesi, M, Mastrangelo, E. | 登録日 | 2013-12-19 | 公開日 | 2014-11-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | PPNDS inhibits murine Norovirus RNA-dependent RNA-polymerase mimicking two RNA stacking bases. Febs Lett., 588, 2014
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4X2Y
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![BU of 4x2y by Molmil](/molmil-images/mine/4x2y) | Crystal structure of a chimeric Murine Norovirus NS6 protease (inactive C139A mutant) in which the P4-P4 prime residues of the cleavage junction in the extended C-terminus have been replaced by the corresponding residues from the NS2-3 junction. | 分子名称: | NS6 Protease,NS6 Protease | 著者 | Leen, E.N, Pfeil, M.-P, Fernandes, H, Curry, S. | 登録日 | 2014-11-27 | 公開日 | 2015-02-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.417 Å) | 主引用文献 | Structure determination of Murine Norovirus NS6 proteases with C-terminal extensions designed to probe protease-substrate interactions. Peerj, 3, 2015
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3UR0
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![BU of 3ur0 by Molmil](/molmil-images/mine/3ur0) | Crystal structures of murine norovirus RNA-dependent RNA polymerase in complex with Suramin | 分子名称: | 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID, RNA-dependent RNA polymerase, SULFATE ION | 著者 | Milani, M, Mastrangelo, E, Bolognesi, M. | 登録日 | 2011-11-21 | 公開日 | 2012-05-02 | 最終更新日 | 2012-05-23 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases. J.Mol.Biol., 419, 2012
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4X2X
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3QID
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![BU of 3qid by Molmil](/molmil-images/mine/3qid) | Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase | 分子名称: | GLYCEROL, MANGANESE (III) ION, RNA dependent RNA polymerase, ... | 著者 | Kim, K.H, Intekhab, A, Lee, J.H. | 登録日 | 2011-01-27 | 公開日 | 2011-12-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase. J.Gen.Virol., 92, 2011
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3SFU
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![BU of 3sfu by Molmil](/molmil-images/mine/3sfu) | crystal structure of murine norovirus RNA dependent RNA polymerase in complex with ribavirin | 分子名称: | 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, GLYCEROL, MAGNESIUM ION, ... | 著者 | Kim, K.H, Alam, I. | 登録日 | 2011-06-14 | 公開日 | 2012-05-09 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase in complex with 2-thiouridine or ribavirin. Virology, 426, 2012
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3NAI
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![BU of 3nai by Molmil](/molmil-images/mine/3nai) | Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase | 分子名称: | 5-FLUOROURACIL, GLYCEROL, MAGNESIUM ION, ... | 著者 | Kim, K.H, Lee, J.H, Alam, I, Park, Y, Kang, S. | 登録日 | 2010-06-02 | 公開日 | 2011-06-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase To be Published
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3UPF
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![BU of 3upf by Molmil](/molmil-images/mine/3upf) | Crystal structure of murine norovirus RNA-dependent RNA polymerase bound to NF023 | 分子名称: | 8-({3-[({3-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl}carbamoyl)amino]benzoyl}amino)naphthalene-1,3,5-trisulfonic acid, RNA-dependent RNA polymerase, SULFATE ION | 著者 | Milani, M, Mastrangelo, E, Bolognesi, M. | 登録日 | 2011-11-18 | 公開日 | 2012-05-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases. J.Mol.Biol., 419, 2012
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4X2W
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![BU of 4x2w by Molmil](/molmil-images/mine/4x2w) | |
3NAH
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![BU of 3nah by Molmil](/molmil-images/mine/3nah) | Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase | 分子名称: | RNA dependent RNA polymerase, SULFATE ION | 著者 | Kim, K.H, Lee, J.H, Alam, I, Park, Y, Kang, S. | 登録日 | 2010-06-02 | 公開日 | 2011-06-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase To be Published
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8A5M
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![BU of 8a5m by Molmil](/molmil-images/mine/8a5m) | TRIM7 PRYSPRY in complex with a MNV1-NS6 peptide LEALEFQ | 分子名称: | E3 ubiquitin-protein ligase TRIM7, MNV1-NS6 peptide LEALEFQ, PHOSPHATE ION | 著者 | Luptak, J. | 登録日 | 2022-06-15 | 公開日 | 2022-07-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.918 Å) | 主引用文献 | TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing. Viruses, 14, 2022
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5Y3D
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2MCD
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2M4G
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![BU of 2m4g by Molmil](/molmil-images/mine/2m4g) | Solution structure of the Core Domain (11-85) of the Murine Norovirus VPg protein | 分子名称: | Murine Norovirus VPg protein | 著者 | Leen, E.N, Kwok, R, Birtley, J.R, Prater, S.N, Simpson, P.J, Matthews, S, Marchant, J, Curry, S. | 登録日 | 2013-02-05 | 公開日 | 2013-03-27 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structures of the Compact Helical Core Domains of Feline Calicivirus and Murine Norovirus VPg Proteins. J.Virol., 87, 2013
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2MCH
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