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PDB: 21 件

4ASH
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Crystal structure of the NS6 protease from murine norovirus 1
分子名称: NS6 PROTEASE
著者Leen, E.N, Baeza, G, Curry, S.
登録日2012-05-01
公開日2012-05-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.578 Å)
主引用文献Structure of a Murine Norovirus Ns6 Protease-Product Complex Revealed by Adventitious Crystallisation.
Plos One, 7, 2012
3UQS
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BU of 3uqs by Molmil
Crystal structures of murine norovirus RNA-dependent RNA polymerase
分子名称: RNA-dependent RNA polymerase, SULFATE ION
著者Milani, M, Mastrangelo, E, Bolognesi, M.
登録日2011-11-21
公開日2012-05-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases.
J.Mol.Biol., 419, 2012
3SFG
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crystal structure of murine norovirus RNA dependent RNA polymerase in complex with 2thiouridine(2TU)
分子名称: 1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one, GLYCEROL, MAGNESIUM ION, ...
著者Kim, K.H, Alam, I.
登録日2011-06-13
公開日2012-05-09
実験手法X-RAY DIFFRACTION (2.209 Å)
主引用文献Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase in complex with 2-thiouridine or ribavirin.
Virology, 426, 2012
4NRU
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Murine Norovirus RNA-dependent-RNA-polymerase in complex with Compound 6, a suramin derivative
分子名称: 4-({4-methyl-3-[(3-nitrobenzoyl)amino]benzoyl}amino)naphthalene-1,5-disulfonic acid, MAGNESIUM ION, RNA dependent RNA polymerase
著者Milani, M, Croci, R, Pezzullo, M, Tarantino, D, Mastrangelo, E, Bolognesi, M.
登録日2013-11-27
公開日2014-10-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds.
Plos One, 9, 2014
4X2V
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Crystal structure of the Murine Norovirus NS6 protease (inactive C139A mutant) with a C-terminal extension to include residue P1 prime of NS7
分子名称: IMIDAZOLE, NS6 Protease
著者Fernandes, H, Leen, E.N, Curry, S.
登録日2014-11-27
公開日2015-02-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure determination of Murine Norovirus NS6 proteases with C-terminal extensions designed to probe protease-substrate interactions.
Peerj, 3, 2015
8A8X
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TRIM7 PRYSPRY in complex with a MNV1-NS3 peptide HDDFGLQ
分子名称: E3 ubiquitin-protein ligase TRIM7, MNV1-NS3 C term peptide
著者Luptak, J.
登録日2022-06-24
公開日2022-07-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing.
Viruses, 14, 2022
4O4R
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BU of 4o4r by Molmil
Murine Norovirus RdRp in complex with PPNDS
分子名称: 3-[(E)-{4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]pyridin-2-yl}diazenyl]-7-nitronaphthalene-1,5-disulfonic acid, RNA-dependent-RNA-polymerase, SULFATE ION
著者Croci, R, Tarantino, D, Milani, M, Pezzullo, M, Bolognesi, M, Mastrangelo, E.
登録日2013-12-19
公開日2014-11-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献PPNDS inhibits murine Norovirus RNA-dependent RNA-polymerase mimicking two RNA stacking bases.
Febs Lett., 588, 2014
4X2Y
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Crystal structure of a chimeric Murine Norovirus NS6 protease (inactive C139A mutant) in which the P4-P4 prime residues of the cleavage junction in the extended C-terminus have been replaced by the corresponding residues from the NS2-3 junction.
分子名称: NS6 Protease,NS6 Protease
著者Leen, E.N, Pfeil, M.-P, Fernandes, H, Curry, S.
登録日2014-11-27
公開日2015-02-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.417 Å)
主引用文献Structure determination of Murine Norovirus NS6 proteases with C-terminal extensions designed to probe protease-substrate interactions.
Peerj, 3, 2015
3UR0
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BU of 3ur0 by Molmil
Crystal structures of murine norovirus RNA-dependent RNA polymerase in complex with Suramin
分子名称: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID, RNA-dependent RNA polymerase, SULFATE ION
著者Milani, M, Mastrangelo, E, Bolognesi, M.
登録日2011-11-21
公開日2012-05-02
最終更新日2012-05-23
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases.
J.Mol.Biol., 419, 2012
4X2X
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Crystal structure of the Murine Norovirus NS6 protease (inactive C139A mutant) with a C-terminal extension to include residues P1 prime - P4 prime of NS7
分子名称: NS6 protease
著者Leen, E.N, Cromwell Jr, H, Fernandes, H, Curry, S.
登録日2014-11-27
公開日2015-02-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.472 Å)
主引用文献Structure determination of Murine Norovirus NS6 proteases with C-terminal extensions designed to probe protease-substrate interactions.
Peerj, 3, 2015
3QID
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BU of 3qid by Molmil
Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase
分子名称: GLYCEROL, MANGANESE (III) ION, RNA dependent RNA polymerase, ...
著者Kim, K.H, Intekhab, A, Lee, J.H.
登録日2011-01-27
公開日2011-12-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase.
J.Gen.Virol., 92, 2011
3SFU
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crystal structure of murine norovirus RNA dependent RNA polymerase in complex with ribavirin
分子名称: 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, GLYCEROL, MAGNESIUM ION, ...
著者Kim, K.H, Alam, I.
登録日2011-06-14
公開日2012-05-09
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase in complex with 2-thiouridine or ribavirin.
Virology, 426, 2012
3NAI
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BU of 3nai by Molmil
Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase
分子名称: 5-FLUOROURACIL, GLYCEROL, MAGNESIUM ION, ...
著者Kim, K.H, Lee, J.H, Alam, I, Park, Y, Kang, S.
登録日2010-06-02
公開日2011-06-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase
To be Published
3UPF
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BU of 3upf by Molmil
Crystal structure of murine norovirus RNA-dependent RNA polymerase bound to NF023
分子名称: 8-({3-[({3-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl}carbamoyl)amino]benzoyl}amino)naphthalene-1,3,5-trisulfonic acid, RNA-dependent RNA polymerase, SULFATE ION
著者Milani, M, Mastrangelo, E, Bolognesi, M.
登録日2011-11-18
公開日2012-05-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases.
J.Mol.Biol., 419, 2012
4X2W
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BU of 4x2w by Molmil
Crystal structure of the Murine Norovirus NS6 protease (inactive C139A mutant) with a C-terminal extension to include residues P1 prime - P2 prime of NS7
分子名称: NS6 Protease
著者Fernandes, H, Leen, E.N, Curry, S.
登録日2014-11-27
公開日2015-02-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure determination of Murine Norovirus NS6 proteases with C-terminal extensions designed to probe protease-substrate interactions.
Peerj, 3, 2015
3NAH
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BU of 3nah by Molmil
Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase
分子名称: RNA dependent RNA polymerase, SULFATE ION
著者Kim, K.H, Lee, J.H, Alam, I, Park, Y, Kang, S.
登録日2010-06-02
公開日2011-06-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase
To be Published
8A5M
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BU of 8a5m by Molmil
TRIM7 PRYSPRY in complex with a MNV1-NS6 peptide LEALEFQ
分子名称: E3 ubiquitin-protein ligase TRIM7, MNV1-NS6 peptide LEALEFQ, PHOSPHATE ION
著者Luptak, J.
登録日2022-06-15
公開日2022-07-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.918 Å)
主引用文献TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing.
Viruses, 14, 2022
5Y3D
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BU of 5y3d by Molmil
Structural insight into the interaction between RNA polymerase and VPg for norovirus replication
分子名称: RNA-dependent RNA polymerase, viral protein genome-linked (VPg)
著者Kim, K.H, Lee, J.-H, Seok, J.H.
登録日2017-07-28
公開日2018-07-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献Insight Into the Interaction Between RNA Polymerase and VPg for Murine Norovirus Replication.
Front Microbiol, 9, 2018
2MCD
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BU of 2mcd by Molmil
Backbone 1H, 13C, and 15N Chemical Shift Assignments for murine norovirus NS1/2 D94E mutant
分子名称: Murine norovirus 1
著者Borin, B, Krezel, A.M.
登録日2013-08-18
公開日2013-12-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Murine norovirus protein NS1/2 aspartate to glutamate mutation, sufficient for persistence, reorients side chain of surface exposed tryptophan within a novel structured domain.
Proteins, 82, 2014
2M4G
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BU of 2m4g by Molmil
Solution structure of the Core Domain (11-85) of the Murine Norovirus VPg protein
分子名称: Murine Norovirus VPg protein
著者Leen, E.N, Kwok, R, Birtley, J.R, Prater, S.N, Simpson, P.J, Matthews, S, Marchant, J, Curry, S.
登録日2013-02-05
公開日2013-03-27
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structures of the Compact Helical Core Domains of Feline Calicivirus and Murine Norovirus VPg Proteins.
J.Virol., 87, 2013
2MCH
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BU of 2mch by Molmil
Backbone 1H, 13C, and 15N Chemical Shift Assignments for murine norovirus NS1/2 CW3 WT
分子名称: Murine norovirus 1
著者Borin, B, Krezel, A.M.
登録日2013-08-20
公開日2013-12-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Murine norovirus protein NS1/2 aspartate to glutamate mutation, sufficient for persistence, reorients side chain of surface exposed tryptophan within a novel structured domain.
Proteins, 82, 2014

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