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PDB: 37 件
6WRT
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BU of 6wrt by Molmil
Crystal structure of Mj 3-nitro-tyrosine tRNA synthetase (5B) C70A/S158C variant bound to 3-nitro-tyrosine
分子名称: META-NITRO-TYROSINE, SODIUM ION, Tyrosine--tRNA ligase
著者Beyer, J.N, Hosseinzadeh, P, Karplus, P.A, Mehl, R.A, Cooley, R.B.
登録日2020-04-30
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Overcoming Near-Cognate Suppression in a Release Factor 1-Deficient Host with an Improved Nitro-Tyrosine tRNA Synthetase.
J.Mol.Biol., 432, 2020
6WRN
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BU of 6wrn by Molmil
Crystal structure of Mj 3-nitro-tyrosine tRNA synthetase (5B) C70A variant bound to 3-nitro-tyrosine
分子名称: META-NITRO-TYROSINE, SODIUM ION, Tyrosine--tRNA ligase
著者Beyer, J.N, Hosseinzadeh, P, Karplus, P.A, Mehl, R.A, Cooley, R.B.
登録日2020-04-29
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Overcoming Near-Cognate Suppression in a Release Factor 1-Deficient Host with an Improved Nitro-Tyrosine tRNA Synthetase.
J.Mol.Biol., 432, 2020
5N5U
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BU of 5n5u by Molmil
Structure of p-boronophenylalanyl tRNA synthetase in complex with p-boronophenylalanine and adenosine monophosphate
分子名称: 4-Borono-L-phenylalanine, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ...
著者Schiefner, A, Skerra, A.
登録日2017-02-14
公開日2018-02-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Basis for the Specific Cotranslational Incorporation of p-Boronophenylalanine into Biosynthetic Proteins.
Biochemistry, 57, 2018
4NDA
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BU of 4nda by Molmil
Crystal structure of 3-nitro-tyrosine tRNA synthetase (5B) bound to 3-nitro-tyrosine
分子名称: GLYCEROL, META-NITRO-TYROSINE, SODIUM ION, ...
著者Cooley, R.B, Driggers, C.M, Karplus, P.A, Mehl, R.A.
登録日2013-10-25
公開日2014-03-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Basis of Improved Second-Generation 3-Nitro-tyrosine tRNA Synthetases.
Biochemistry, 53, 2014
2ZP1
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BU of 2zp1 by Molmil
Structual basis of iodo-tyrosine recognition by engineered archeal tyrosyl-tRNA synthetase
分子名称: 3-IODO-TYROSINE, Tyrosyl-tRNA synthetase
著者Oki, K, Kobayashi, T, Sakamoto, K, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-06-22
公開日2009-02-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structual Basis of Iodo-Tyrosine Recognition by Engineered Archeal Tyrosyl-tRNA Synthetase
To be Published
7C5C
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BU of 7c5c by Molmil
Crystal structure of SeFRS
分子名称: 1,2-ETHANEDIOL, Tyrosine--tRNA ligase
著者Sun, J.P, Wang, J.Y, Zhu, Z.L, He, Q.T.
登録日2020-05-19
公開日2021-05-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献CRYSTAL STRUCTURE OF SeFRS
To Be Published
7CKH
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BU of 7ckh by Molmil
Crystal structure of TMSiPheRS
分子名称: Tyrosine--tRNA ligase
著者Sun, J.P, Wang, J.Y, Zhu, Z.L, He, Q.T, Xiao, P.
登録日2020-07-17
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.79492676 Å)
主引用文献DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1 H-NMR probe.
Nat Commun, 11, 2020
6WRQ
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BU of 6wrq by Molmil
Crystal structure of Mj 3-nitro-tyrosine tRNA synthetase (5B) S158C variant bound to 3-nitro-tyrosine
分子名称: GLYCEROL, META-NITRO-TYROSINE, SODIUM ION, ...
著者Beyer, J.N, Hosseinzadeh, P, Karplus, P.A, Mehl, R.A, Cooley, R.B.
登録日2020-04-29
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Overcoming Near-Cognate Suppression in a Release Factor 1-Deficient Host with an Improved Nitro-Tyrosine tRNA Synthetase.
J.Mol.Biol., 432, 2020
2AG6
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BU of 2ag6 by Molmil
Crystal structure of p-bromo-l-phenylalanine-tRNA sythetase in complex with p-bromo-l-phenylalanine
分子名称: 4-BROMO-L-PHENYLALANINE, Tyrosyl-tRNA synthetase
著者Turner, J.M, Graziano, J, Spraggon, G, Schultz, P.G.
登録日2005-07-26
公開日2006-04-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural plasticity of an aminoacyl-tRNA synthetase active site
Proc.Natl.Acad.Sci.Usa, 103, 2006
5L7P
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BU of 5l7p by Molmil
In silico-powered specific incorporation of photocaged Dopa at multiple protein sites
分子名称: (2~{S})-2-azanyl-3-[3-[(2-nitrophenyl)methoxy]-4-oxidanyl-phenyl]propanoic acid, CALCIUM ION, CHLORIDE ION, ...
著者Hauf, M, Richter, F, Schneider, T, Martins, B.M, Baumann, T, Durkin, P, Dobbek, H, Moeglich, A, Budisa, N.
登録日2016-06-03
公開日2017-09-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Photoactivatable Mussel-Based Underwater Adhesive Proteins by an Expanded Genetic Code.
Chembiochem, 18, 2017
4PBT
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BU of 4pbt by Molmil
Crystal structure of the M. jannaschii G2 tRNA synthetase variant bound to 4-trans-cyclooctene-amidopheylalanine (Tco-amF)
分子名称: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 4-{[(1R,4E)-cyclooct-4-en-1-ylcarbonyl]amino}-L-phenylalanine, GLYCEROL, ...
著者Cooley, R.B, Karplus, P.A, Mehl, R.A.
登録日2014-04-13
公開日2014-07-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Gleaning Unexpected Fruits from Hard-Won Synthetases: Probing Principles of Permissivity in Non-canonical Amino Acid-tRNA Synthetases.
Chembiochem, 15, 2014
4PBR
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BU of 4pbr by Molmil
Crystal structure of the M. jannaschii G2 tRNA synthetase variant bound to 4-(2-bromoisobutyramido)-phenylalanine (BibaF)
分子名称: 4-[(2-bromo-2-methylpropanoyl)amino]-L-phenylalanine, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Cooley, R.B, Karplus, P.A, Mehl, R.A.
登録日2014-04-13
公開日2014-07-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Gleaning Unexpected Fruits from Hard-Won Synthetases: Probing Principles of Permissivity in Non-canonical Amino Acid-tRNA Synthetases.
Chembiochem, 15, 2014
1ZH0
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BU of 1zh0 by Molmil
Crystal Structure of L-3-(2-napthyl)alanine-tRNA synthetase in complex with L-3-(2-napthyl)alanine
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-(2-NAPHTHYL)-ALANINE, Tyrosyl-tRNA synthetase
著者Turner, J.M, Graziano, J, Spraggon, G, Schultz, P.G.
登録日2005-04-22
公開日2006-04-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural plasticity of an aminoacyl-tRNA synthetase active site
Proc.Natl.Acad.Sci.Usa, 103, 2006
6WRK
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BU of 6wrk by Molmil
Crystal structure of 3rd-generation Mj 3-nitro-tyrosine tRNA synthetase ("A7") bound to 3-nitro-tyrosine
分子名称: GLYCEROL, META-NITRO-TYROSINE, SODIUM ION, ...
著者Beyer, J.N, Hosseinzadeh, P, Karplus, P.A, Mehl, R.A, Cooley, R.B.
登録日2020-04-29
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Overcoming Near-Cognate Suppression in a Release Factor 1-Deficient Host with an Improved Nitro-Tyrosine tRNA Synthetase.
J.Mol.Biol., 432, 2020
1J1U
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BU of 1j1u by Molmil
Crystal structure of archaeal tyrosyl-tRNA synthetase complexed with tRNA(Tyr) and L-tyrosine
分子名称: MAGNESIUM ION, TYROSINE, Tyrosyl-tRNA synthetase, ...
著者Kobayashi, T, Nureki, O, Ishitani, R, Tukalo, M, Cusack, S, Sakamoto, K, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-12-17
公開日2003-06-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic code expansion
NAT.STRUCT.BIOL., 10, 2003
2PXH
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BU of 2pxh by Molmil
Crystal structure of a bipyridylalanyl-tRNA synthetase
分子名称: 3-(2,2'-BIPYRIDIN-5-YL)-L-ALANINE, Tyrosyl-tRNA synthetase
著者Liu, W, Xie, J, Schultz, P.G.
登録日2007-05-14
公開日2008-02-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献A genetically encoded bidentate, metal-binding amino acid.
Angew.Chem.Int.Ed.Engl., 46, 2007
4HPW
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BU of 4hpw by Molmil
Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine
分子名称: 3-methoxy-L-tyrosine, Tyrosine--tRNA ligase
著者Yu, Y, Zhou, Q, Dong, J, Li, J, Xiaoxuan, L, Mukherjee, A, Ouyang, H, Nilges, M, Li, H, Gao, F, Gong, W, Lu, Y, Wang, J.
登録日2012-10-24
公開日2013-10-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine
To be Published
4ND7
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BU of 4nd7 by Molmil
Crystal structure of apo 3-nitro-tyrosine tRNA synthetase (5B) in the closed form
分子名称: BETA-MERCAPTOETHANOL, SODIUM ION, Tyrosine--tRNA ligase
著者Cooley, R.B, Driggers, C.M, Karplus, P.A, Mehl, R.A.
登録日2013-10-25
公開日2014-03-19
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis of Improved Second-Generation 3-Nitro-tyrosine tRNA Synthetases.
Biochemistry, 53, 2014
4NX2
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BU of 4nx2 by Molmil
Crystal structure of DCYRS complexed with DCY
分子名称: 3,5-dichloro-L-tyrosine, Tyrosine--tRNA ligase
著者Wang, J, Gong, W, Li, J, Gao, F, Li, H.
登録日2013-12-08
公開日2014-09-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers.
J.Am.Chem.Soc., 136, 2014
4ND6
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BU of 4nd6 by Molmil
Crystal structure of apo 3-nitro-tyrosine tRNA synthetase (5B) in the open form
分子名称: GLYCEROL, Tyrosine-tRNA ligase
著者Cooley, R.B, Driggers, C.M, Karplus, P.A, Mehl, R.A.
登録日2013-10-25
公開日2014-03-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis of Improved Second-Generation 3-Nitro-tyrosine tRNA Synthetases.
Biochemistry, 53, 2014
4PBS
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BU of 4pbs by Molmil
Crystal structure of the M. jannaschii F9 tRNA synthetase variant bound to 4-(2-bromoisobutyramido)-phenylalanine (BibaF)
分子名称: 4-[(2-bromo-2-methylpropanoyl)amino]-L-phenylalanine, Tyrosine--tRNA ligase
著者Cooley, R.B, Karplus, P.A, Mehl, R.A.
登録日2014-04-13
公開日2014-07-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.011 Å)
主引用文献Gleaning Unexpected Fruits from Hard-Won Synthetases: Probing Principles of Permissivity in Non-canonical Amino Acid-tRNA Synthetases.
Chembiochem, 15, 2014
7CKG
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BU of 7ckg by Molmil
Crystal structure of TMSiPheRS complexed with TMSiPhe
分子名称: 4-(trimethylsilyl)-L-phenylalanine, Tyrosine--tRNA ligase
著者Sun, J.P, Wang, J.Y, Zhu, Z.L, He, Q.T, Xiao, P.
登録日2020-07-17
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.053 Å)
主引用文献DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1 H-NMR probe.
Nat Commun, 11, 2020
3D6V
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BU of 3d6v by Molmil
Crystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetase
分子名称: 4-(2,2,2-TRIFLUOROETHYL)-L-PHENYLALANINE, BETA-MERCAPTOETHANOL, Tyrosyl-tRNA synthetase
著者Liu, W, Tippmann, E, Mack, A.V, Schultz, P.G.
登録日2008-05-20
公開日2008-05-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A genetically encoded diazirine photocrosslinker in Escherichia coli
ChemBioChem, 8, 2007
3D6U
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BU of 3d6u by Molmil
Crystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetase
分子名称: 4-[3-(TRIFLUOROMETHYL)DIAZIRIDIN-3-YL]-L-PHENYLALANINE, BETA-MERCAPTOETHANOL, Tyrosyl-tRNA synthetase
著者Liu, W, Tippmann, E, Mack, A.V, Schultz, P.G.
登録日2008-05-20
公開日2008-05-27
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A genetically encoded diazirine photocrosslinker in Escherichia coli
ChemBioChem, 8, 2007
4HK4
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BU of 4hk4 by Molmil
Crystal structure of apo Tyrosine-tRNA ligase mutant protein
分子名称: DI(HYDROXYETHYL)ETHER, Tyrosine--tRNA ligase
著者Yu, Y, Zhou, Q, Dong, J, Li, J, Xiaoxuan, L, Mukherjee, A, Ouyang, H, Nilges, M, Li, H, Gao, F, Gong, W, Lu, Y, Wang, J.
登録日2012-10-15
公開日2013-04-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.298 Å)
主引用文献Crystal structure of apo Tyrosine-tRNA ligase mutant protein
To be Published

 

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