6WRK

Crystal structure of 3rd-generation Mj 3-nitro-tyrosine tRNA synthetase ("A7") bound to 3-nitro-tyrosine

Summary for 6WRK

• Entry DOI: 10.2210/pdb6wrk/pdb
• Related: 4NDA 6WRN 6WRQ 6WRT
• Descriptor: Tyrosine--tRNA ligase, GLYCEROL, SODIUM ION, ... (5 entities in total)
• Functional Keywords: aminoacyl-trna synthetase, 3-nitro-tyrosine, ligase
• Biological source: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
• Total number of polymer chains: 1
• Total formula weight: 36888.54

Authors

Beyer, J.N.,Hosseinzadeh, P.,Karplus, P.A.,Mehl, R.A.,Cooley, R.B. (deposition date: 2020-04-29, release date: 2020-07-01, Last modification date: 2023-10-18)

• Primary citation: Beyer, J.N.,Hosseinzadeh, P.,Gottfried-Lee, I.,Van Fossen, E.M.,Zhu, P.,Bednar, R.M.,Karplus, P.A.,Mehl, R.A.,Cooley, R.B.; Overcoming Near-Cognate Suppression in a Release Factor 1-Deficient Host with an Improved Nitro-Tyrosine tRNA Synthetase.; J.Mol.Biol., 432:4690-4704, 2020; PubMed: 32569745; DOI: 10.1016/j.jmb.2020.06.014

Experimental method

X-RAY DIFFRACTION (1.95 Å)