5EOT
| Structure of HLA-A2:01 with peptide G13E | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Zajonc, D.M, Remesh, S.G. | 登録日 | 2015-11-10 | 公開日 | 2016-12-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT. J. Biol. Chem., 292, 2017
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6VB7
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3L3G
| Crystal structure of HLA-B*4402 in complex with the R5A mutant of a self-peptide derived from DPA*0201 | 分子名称: | ACETATE ION, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Theodossis, A, Ely, L.K, Rossjohn, J. | 登録日 | 2009-12-16 | 公開日 | 2010-03-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition Proc.Natl.Acad.Sci.USA, 107, 2010
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5CS7
| The crystal structure of wt beta2-microglobulin at room temperature | 分子名称: | Beta-2-microglobulin | 著者 | de Rosa, M, Mota, C.S, de Sanctis, D, Bolognesi, M, Ricagno, S. | 登録日 | 2015-07-23 | 公開日 | 2016-08-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity. Nat Commun, 9, 2018
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2F53
| Directed Evolution of Human T-cell Receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without apparent cross-reactivity | 分子名称: | Beta-2-microglobulin, Cancer/testis antigen 1B, GLYCEROL, ... | 著者 | Rizkallah, P.J, Jakobsen, B.K, Dunn, S.M, Sami, M. | 登録日 | 2005-11-25 | 公開日 | 2006-04-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity. Protein Sci., 15, 2006
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3DX8
| Crystal Structure of B*4405 presenting a 10mer EBV epitope | 分子名称: | Beta-2-microglobulin, EBV decapeptide epitope, GLYCEROL, ... | 著者 | Archbold, J.K, Ely, L.K, Rossjohn, J. | 登録日 | 2008-07-23 | 公開日 | 2009-01-27 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition. J.Exp.Med., 206, 2009
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3IXA
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4X6E
| CD1a binary complex with lysophosphatidylcholine | 分子名称: | (4R,7R,18Z)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide, Beta-2-microglobulin, D-MALATE, ... | 著者 | Birkinshaw, R.W, Rossjohn, J. | 登録日 | 2014-12-08 | 公開日 | 2015-01-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | alpha beta T cell antigen receptor recognition of CD1a presenting self lipid ligands. Nat.Immunol., 16, 2015
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6GH1
| HLA-E*01:03 in complex with Mtb44 | 分子名称: | Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], MHC class I antigen, ... | 著者 | Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K. | 登録日 | 2018-05-04 | 公開日 | 2018-08-08 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding. Nat Commun, 9, 2018
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6VPZ
| HLA-B*27:05 presenting an HIV-1 11mer peptide | 分子名称: | 11-mer peptide, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N. | 登録日 | 2020-02-04 | 公開日 | 2021-02-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Epitope length variants balance protective immune responses and viral escape in HIV-1 infection Cell Rep, 38, 2022
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1HSA
| THE THREE-DIMENSIONAL STRUCTURE OF HLA-B27 AT 2.1 ANGSTROMS RESOLUTION SUGGESTS A GENERAL MECHANISM FOR TIGHT PEPTIDE BINDING TO MHC | 分子名称: | BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-B*2705), MODEL PEPTIDE SEQUENCE - ARAAAAAAA | 著者 | Madden, D.R, Gorga, J.C, Strominger, J.L, Wiley, D.C. | 登録日 | 1992-08-11 | 公開日 | 1992-10-15 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The three-dimensional structure of HLA-B27 at 2.1 A resolution suggests a general mechanism for tight peptide binding to MHC. Cell(Cambridge,Mass.), 70, 1992
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7Q9A
| MHC Class I A02 Allele presenting LLLGIGILVL, in complex with Mel5 TCR | 分子名称: | Beta-2-microglobulin, GLYCEROL, Human Mel5 T Cell Receptor, ... | 著者 | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | 登録日 | 2021-11-12 | 公開日 | 2023-02-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell, 186, 2023
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1JGE
| HLA-B*2705 bound to nona-peptide m9 | 分子名称: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-27 B*2705 ALPHA CHAIN, ... | 著者 | Hulsmeyer, M, Hillig, R.C, Volz, A, Ruhl, M, Schroder, W, Saenger, W, Ziegler, A, Uchanska-Ziegler, B. | 登録日 | 2001-06-25 | 公開日 | 2002-10-30 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | HLA-B27 subtypes differentially associated with disease exhibit subtle structural
alterations J.Biol.Chem., 277, 2002
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3MRI
| Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide G4M-V5W variant | 分子名称: | 9-meric peptide from Serine protease/NTPase/helicase NS3, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Reiser, J.-B, Le Gorrec, M, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | 登録日 | 2010-04-29 | 公開日 | 2011-05-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide G4M-V5W variant To be Published
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5T70
| KIR3DL1 in complex with HLA-B*57:01 presenting TSNLQEQIGW | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Decapeptide: THR-SER-ASN-LEU-GLN-GLU-GLN-ILE-GLY-TRP, ... | 著者 | Pymm, P, Rossjohn, J, Vivian, J.P. | 登録日 | 2016-09-02 | 公開日 | 2017-03-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape. Nat. Struct. Mol. Biol., 24, 2017
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3MRP
| Crystal Structure of MHC class I HLA-A2 molecule complexed with Melan-A MART1 decapeptide variant | 分子名称: | 10-meric peptide from Melanoma antigen recognized by T-cells 1, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Reiser, J.-B, Chouquet, A, Le Gorrec, M, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | 登録日 | 2010-04-29 | 公開日 | 2011-05-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of MHC class I HLA-A2 molecule complexed with Melan-A MART1 decapeptide variant To be Published
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3MV8
| Crystal Structure of the TK3-Gln55His TCR in complex with HLA-B*3501/HPVG | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... | 著者 | Gras, S, Chen, Z, Miles, J.J, Liu, Y.C, Bell, M.J, Sullivan, L.C, Kjer-Nielsen, L, Brennan, R.M, Burrows, J.M, Neller, M.A, Khanna, R, Purcell, A.W, Brooks, A.G, McCluskey, J, Rossjohn, J, Burrows, S.R. | 登録日 | 2010-05-03 | 公開日 | 2010-06-09 | 最終更新日 | 2011-07-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Allelic polymorphism in the T cell receptor and its impact on immune responses J.Exp.Med., 207, 2010
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3DTX
| Crystal structure of HLA-B*2705 complexed with the double citrullinated vasoactive intestinal peptide type 1 receptor (VIPR) peptide (residues 400-408) | 分子名称: | Beta-2-microglobulin, Double citrullinated vasoactive intestinal polypeptide receptor, MHC class I antigen (Fragment) | 著者 | Beltrami, A, Gabdulkhakov, A, Rossmann, M, Ziegler, A, Uchanska-Ziegler, B, Saenger, W. | 登録日 | 2008-07-16 | 公開日 | 2009-05-05 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Citrullination-and mhc polymorphism-dependent conformational changes of a self peptide To be Published
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5EUO
| PF6-M1-HLA-A2 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Yang, X. | 登録日 | 2015-11-18 | 公開日 | 2016-11-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of PF6-M1-HLA-A2 complex To Be Published
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2D4D
| The Crystal Structure of human beta2-microglobulin, L39W W60F W95F Mutant | 分子名称: | Beta-2-microglobulin, SODIUM ION | 著者 | Iwata, K, Matsuura, T, Nakagawa, A, Goto, Y. | 登録日 | 2005-10-17 | 公開日 | 2006-08-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Conformation of Amyloid Fibrils of beta2-Microglobulin Probed by Tryptophan Mutagenesis J.Biol.Chem., 281, 2006
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4NO5
| Crystal structure of non-phosphorylated form of AMPD2 phosphopeptide bound to HLA-A2 | 分子名称: | 1,2-ETHANEDIOL, AMP deaminase 2, Beta-2-microglobulin, ... | 著者 | Mohammed, F, Stones, D.H, Willcox, B.E. | 登録日 | 2013-11-19 | 公開日 | 2014-12-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status. Oncotarget, 8, 2017
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4NNX
| Crystal structure of PKD2 phosphopeptide bound to HLA-A2 | 分子名称: | Beta-2-microglobulin, CADMIUM ION, GLYCEROL, ... | 著者 | Mohammed, F, Stones, D.H, Willcox, B.E. | 登録日 | 2013-11-19 | 公開日 | 2014-11-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.104 Å) | 主引用文献 | The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status. Oncotarget, 8, 2017
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7MXH
| CD1c with antigen analogue 3 | 分子名称: | (2S)-2,3-dihydroxypropyl hexadecanoate, 2,6-anhydro-1-deoxy-1,1-difluoro-1-[(R)-hydroxy{[(4S,8S,12S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl]oxy}phosphoryl]-D-glycero-D-galacto-heptitol, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Cao, T.P, Shahine, A, Rossjohn, J. | 登録日 | 2021-05-19 | 公開日 | 2021-11-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells. J.Biol.Chem., 297, 2021
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7EJN
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8EK5
| Engineered scFv 10LH bound to PHOX2B/HLA-A24:02 | 分子名称: | 10LH single chain fragment variable (scFv), Beta-2-microglobulin, GLYCEROL, ... | 著者 | Garfinkle, S.E, Florio, T.J, Sgourakis, N.G. | 登録日 | 2022-09-20 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion. Sci Immunol, 8, 2023
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