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PDB: 45 件
2H43
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Crystal Structure of Human Fragment D Complexed with Ala-His-Arg-Pro-amide
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Doolittle, R.F, Pandi, L.
登録日2006-05-23
公開日2006-12-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Differences in Binding Specificity for the Homologous gamma- and beta-Chain "Holes" on Fibrinogen: Exclusive Binding of Ala-His-Arg-Pro-amide by the beta-Chain Hole.
Biochemistry, 45, 2006
2VDP
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Integrin AlphaIIbBeta3 Headpiece Bound to Fibrinogen Gamma chain peptide,LGGAKQAGDV
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN, ...
著者Springer, T.A, Zhu, J, Xiao, T.
登録日2007-10-10
公開日2008-09-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
1LTJ
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Crystal Structure of Recombinant Human Fibrinogen Fragment D with the Peptide Ligands Gly-Pro-Arg-Pro-Amide and Gly-His-Arg-Pro-Amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen Beta chain, ...
著者Kostelansky, M.S, Betts, L, Gorkun, O.V, Lord, S.T.
登録日2002-05-20
公開日2002-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献2.8 A Crystal Structures of Recombinant Fibrinogen Fragment D with and without Two Peptide Ligands: GHRP Binding to the "b" Site Disrupts Its Nearby Calcium-binding Site.
Biochemistry, 41, 2002
2Q9I
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BU of 2q9i by Molmil
Crystal Structure of D-Dimer from Human Fibrin Complexed with Met-His-Arg-Pro-Tyr-amide.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrin B Knob (GHRPam), ...
著者Doolittle, R.F, Pandi, L.
登録日2007-06-12
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini
Biochemistry, 46, 2007
1LT9
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Crystal Structure of Recombinant Human Fibrinogen Fragment D
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
著者Kostelansky, M.S, Betts, L, Gorkun, O.V, Lord, S.T.
登録日2002-05-20
公開日2002-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献2.8 A Crystal Structures of Recombinant Fibrinogen Fragment D with and without Two Peptide Ligands: GHRP Binding to the "b" Site Disrupts Its Nearby Calcium-binding Site.
Biochemistry, 41, 2002
1RF0
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BU of 1rf0 by Molmil
Crystal Structure of Fragment D of gammaE132A Fibrinogen
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
著者Kostelansky, M.S, Gorkun, O.V, Lord, S.T.
登録日2003-11-07
公開日2004-03-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Calcium-Binding Site beta2, Adjacent to the "b" Polymerization Site, Modulates Lateral Aggregation of Protofibrils during Fibrin Polymerization.
Biochemistry, 43, 2004
2FFD
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BU of 2ffd by Molmil
Fibrinogen Fragment D with "A" knob peptide mimic GPRVVE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E Chain, ...
著者Betts, L.
登録日2005-12-19
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献The structure of fibrinogen fragment D with the 'A' knob peptide GPRVVE.
THROMB.HAEMOST., 4, 2006
1FZA
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CRYSTAL STRUCTURE OF FIBRINOGEN FRAGMENT D
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN
著者Spraggon, G, Everse, S.J, Doolittle, R.F.
登録日1997-08-05
公開日1997-12-03
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structures of fragment D from human fibrinogen and its crosslinked counterpart from fibrin.
Nature, 389, 1997
3GHG
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Crystal Structure of Human Fibrinogen
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A knob, B knob, ...
著者Doolittle, R.F, Kollman, J.M, Sawaya, M.R, Pandi, L, Riley, M.
登録日2009-03-03
公開日2009-05-19
最終更新日2023-05-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of human fibrinogen.
Biochemistry, 48, 2009
2HPC
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BU of 2hpc by Molmil
Crystal structure of fragment D from Human Fibrinogen Complexed with Gly-Pro-Arg-Pro-amide.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha chain, ...
著者Doolittle, R.F, Kollman, J.M, Chen, A, Pandi, L.
登録日2006-07-17
公開日2007-05-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献

1FZB
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BU of 1fzb by Molmil
CRYSTAL STRUCTURE OF CROSSLINKED FRAGMENT D
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN, ...
著者Spraggon, G, Everse, S.J, Doolittle, R.F.
登録日1997-08-05
公開日1997-12-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structures of fragment D from human fibrinogen and its crosslinked counterpart from fibrin.
Nature, 389, 1997
2HOD
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BU of 2hod by Molmil
Crystal Structure of Fragment D from Human Fibrinogen Complexed with Gly-hydroxyPro-Arg-Pro-amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha chain, ...
著者Doolittle, R.F, Kollman, J.M, Chen, A, Pandi, L.
登録日2006-07-14
公開日2007-05-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献

1FZE
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CRYSTAL STRUCTURE OF FRAGMENT DOUBLE-D FROM HUMAN FIBRIN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN
著者Everse, S.J, Spraggon, G, Veerapandian, L, Doolittle, R.F.
登録日1998-12-23
公開日1999-06-08
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
Biochemistry, 38, 1999
3HUS
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BU of 3hus by Molmil
Crystal structure of recombinant gamma N308K fibrinogen fragment D with the peptide ligand Gly-Pro-Arg-Pro-amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha chain, ...
著者Lord, S.T, Bowley, S.R, Okumura, N.
登録日2009-06-15
公開日2009-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Impaired protofibril formation in fibrinogen gammaN308K is due to altered D:D and "A:a" interactions.
Biochemistry, 48, 2009
1N86
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BU of 1n86 by Molmil
Crystal structure of human D-dimer from cross-linked fibrin complexed with GPR and GHRPLDK peptide ligands.
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, CALCIUM ION, Fibrin alpha/alpha-E chain, ...
著者Yang, Z, Pandi, L, Doolittle, R.F.
登録日2002-11-19
公開日2003-01-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface.
Biochemistry, 41, 2002
2XNX
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BU of 2xnx by Molmil
BC1 fragment of streptococcal M1 protein in complex with human fibrinogen
分子名称: FIBRINOGEN ALPHA CHAIN, FIBRINOGEN BETA CHAIN, FIBRINOGEN GAMMA CHAIN, ...
著者Macheboeuf, P, Y Fu, C, Zinkernagel, A.S, Johnson, J.E, Nizet, V, Ghosh, P.
登録日2010-08-06
公開日2011-04-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Streptococcal M1 Protein Constructs a Pathological Host Fibrinogen Network
Nature, 472, 2011
3H32
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BU of 3h32 by Molmil
Crystal structure of D-dimer from human fibrin complexed with Gly-His-Arg-Pro-Tyr-amide
分子名称: CALCIUM ION, Fibrin B knob pentapeptide, Fibrinogen alpha chain, ...
著者Doolittle, R.F, Pandi, L.
登録日2009-04-15
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Two families of synthetic peptides that enhance fibrin turbidity and delay fibrinolysis by different mechanisms.
Biochemistry, 48, 2009
2A45
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Crystal structure of the complex between thrombin and the central "E" region of fibrin
分子名称: D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Fibrinogen alpha chain, Fibrinogen beta chain, ...
著者Pechik, I, Madrazo, J, Gilliland, G.L, Medved, L.
登録日2005-06-27
公開日2006-05-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献Structural basis for sequential cleavage of fibrinopeptides upon fibrin assembly.
Biochemistry, 45, 2006
1N8E
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Fragment Double-D from Human Fibrin
分子名称: Fibrin alpha/alpha-E chain, Fibrin beta chain, Fibrin gamma chain
著者Yang, Z, Pandi, L, Doolittle, R.F.
登録日2002-11-20
公開日2003-01-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献The Crystal Structure of Fragment Double-D from Cross-Linked Lamprey Fibrin Reveals Isopeptide Linkages across an Unexpected D-D Interface
Biochemistry, 41, 2002
2XNY
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A fragment of streptococcal M1 protein in complex with human fibrinogen
分子名称: FIBRINOGEN ALPHA CHAIN, FIBRINOGEN BETA CHAIN, FIBRINOGEN GAMMA CHAIN, ...
著者Macheboeuf, P, Y Fu, C, Zinkernagel, A.S, Johnson, J.E, Nizet, V, Ghosh, P.
登録日2010-08-06
公開日2011-04-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (7.5 Å)
主引用文献Streptococcal M1 Protein Constructs a Pathological Host Fibrinogen Network
Nature, 472, 2011
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