6Z6J
 
 | | Cryo-EM structure of yeast Lso2 bound to 80S ribosomes under native condition | | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | | 著者 | Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. | | 登録日 | 2020-05-28 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
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6HD7
 | | Cryo-EM structure of the ribosome-NatA complex | | 分子名称: | 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, 5.8S rRNA, 5S rRNA, ... | | 著者 | Knorr, A.G, Becker, T, Beckmann, R. | | 登録日 | 2018-08-17 | | 公開日 | 2018-12-19 | | 最終更新日 | 2019-01-16 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Ribosome-NatA architecture reveals that rRNA expansion segments coordinate N-terminal acetylation.
Nat. Struct. Mol. Biol., 26, 2019
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4U56
 | | Crystal structure of Blasticidin S bound to the yeast 80S ribosome | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | | 登録日 | 2014-07-24 | | 公開日 | 2014-10-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
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5DGE
 | | Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. | | 登録日 | 2015-08-27 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | | 主引用文献 | Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
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7OHW
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6N8O
 | | Cryo-EM structure of Rpl10-inserted (RI) pre-60S ribosomal subunit | | 分子名称: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | | 著者 | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | | 登録日 | 2018-11-29 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
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6N8J
 | | Cryo-EM structure of late nuclear (LN) pre-60S ribosomal subunit | | 分子名称: | 5.8S rRNA, 5S rRNA, 60S ribosomal protein L11-A, ... | | 著者 | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | | 登録日 | 2018-11-29 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
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6N8M
 | | Cryo-EM structure of pre-Lsg1 (PL) pre-60S ribosomal subunit | | 分子名称: | 5.8S RNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | | 著者 | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | | 登録日 | 2018-11-29 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
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5MEI
 | | Crystal structure of Agelastatin A bound to the 80S ribosome | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | McClary, B, Zinshteyn, B, Meyer, M, Jouanneau, M, Pellegrino, S, Yusupova, G, Schuller, A, Reyes, J.C.P, Lu, J, Luo, C, Dang, Y, Romo, D, Yusupov, M, Green, R, Liu, J.O. | | 登録日 | 2016-11-15 | | 公開日 | 2017-06-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A.
Cell Chem Biol, 24, 2017
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6QTZ
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5JUP
 | | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure II (mid-rotated 40S subunit) | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ... | | 著者 | Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A. | | 登録日 | 2016-05-10 | | 公開日 | 2016-10-05 | | 最終更新日 | 2019-11-27 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
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5TGM
 | | Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... | | 著者 | Melnikov, S, Mailliot, J, Yusupov, M. | | 登録日 | 2016-09-28 | | 公開日 | 2017-01-18 | | 最終更新日 | 2022-12-07 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Molecular insights into protein synthesis with proline residues.
EMBO Rep., 17, 2016
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6N8L
 | | Cryo-EM structure of early cytoplasmic-late (ECL) pre-60S ribosomal subunit | | 分子名称: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | | 著者 | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | | 登録日 | 2018-11-29 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
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6R84
 | | Yeast Vms1 (Q295L)-60S ribosomal subunit complex (pre-state with Arb1) | | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Su, T, Izawa, T, Cheng, J, Yamashita, Y, Berninghausen, O, Inada, T, Neupert, W, Beckmann, R. | | 登録日 | 2019-03-31 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis.
Nature, 570, 2019
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4U4O
 | | Crystal structure of Geneticin bound to the yeast 80S ribosome | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | | 登録日 | 2014-07-24 | | 公開日 | 2014-10-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
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6EM1
 | | State C (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | | 著者 | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | | 登録日 | 2017-10-01 | | 公開日 | 2017-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
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6N8K
 | | Cryo-EM structure of early cytoplasmic-immediate (ECI) pre-60S ribosomal subunit | | 分子名称: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | | 著者 | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | | 登録日 | 2018-11-29 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
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5Z3G
 | | Cryo-EM structure of a nucleolar pre-60S ribosome (Rpf1-TAP) | | 分子名称: | 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | | 著者 | Zhu, X, Zhou, D, Ye, K. | | 登録日 | 2018-01-06 | | 公開日 | 2018-04-11 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | | 主引用文献 | Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate.
Protein Cell, 10, 2019
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7OHU
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5NDG
 | | Crystal structure of geneticin (G418) bound to the yeast 80S ribosome | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. | | 登録日 | 2017-03-08 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5NDW
 | | Crystal structure of aminoglycoside TC007 bound to the yeast 80S ribosome | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. | | 登録日 | 2017-03-09 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6C0F
 | | Yeast nucleolar pre-60S ribosomal subunit (state 2) | | 分子名称: | 5.8S rRNA, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... | | 著者 | Sanghai, Z.A, Miller, L, Barandun, J, Hunziker, M, Chaker-Margot, M, Klinge, S. | | 登録日 | 2017-12-29 | | 公開日 | 2018-03-14 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Modular assembly of the nucleolar pre-60S ribosomal subunit.
Nature, 556, 2018
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8CMJ
 | | Translocation intermediate 4 (TI-4*) of 80S S. cerevisiae ribosome with eEF2 in the absence of sordarin | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | | 登録日 | 2023-02-20 | | 公開日 | 2023-09-20 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.79 Å) | | 主引用文献 | mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
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6YLY
 | | pre-60S State NE2 (TAP-Flag-Nop53) | | 分子名称: | 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | | 著者 | Kater, L, Beckmann, R. | | 登録日 | 2020-04-07 | | 公開日 | 2020-07-29 | | 最終更新日 | 2020-09-02 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Mol.Cell, 79, 2020
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6N8N
 | | Cryo-EM structure of Lsg1-engaged (LE) pre-60S ribosomal subunit | | 分子名称: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | | 著者 | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | | 登録日 | 2018-11-29 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
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