Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 9 件
8R5M
DownloadVisualize
BU of 8r5m by Molmil
E-selectin complexed with glycomimetic ligand DS0567
分子名称: (2~{S})-3-cyclohexyl-2-[(2~{R},3~{R},4~{S},5~{S},6~{R})-2-[(1~{R},2~{R},3~{S})-3-ethyl-2-[(2~{S},3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-cyclohexyl]oxy-6-(hydroxymethyl)-5-oxidanyl-3-(phenylcarbonyloxy)oxan-4-yl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Jakob, R.P, Ernst, B, Maier, T.
登録日2023-11-17
公開日2024-10-23
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Analogues of the pan-selectin antagonist rivipansel (GMI-1070).
Eur.J.Med.Chem., 272, 2024
8R5L
DownloadVisualize
BU of 8r5l by Molmil
E-selectin complexed with glycomimetic ligand BW850
分子名称: (2~{S})-3-cyclohexyl-2-[(2~{R},3~{R},4~{S},5~{S},6~{R})-2-[(1~{R},2~{R},3~{S},5~{R})-3-ethyl-2-[(2~{S},3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-[3-[1-[3-oxidanylidene-3-[(3,6,8-trisulfonaphthalen-1-yl)amino]propyl]-1,2,3-triazol-4-yl]propylcarbamoyl]cyclohexyl]oxy-6-(hydroxymethyl)-5-oxidanyl-3-(phenylcarbonyloxy)oxan-4-yl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Jakob, R.P, Ernst, B, Maier, T.
登録日2023-11-17
公開日2024-10-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Analogues of the pan-selectin antagonist rivipansel (GMI-1070).
Eur.J.Med.Chem., 272, 2024
1G1T
DownloadVisualize
BU of 1g1t by Molmil
CRYSTAL STRUCTURE OF E-SELECTIN LECTIN/EGF DOMAINS COMPLEXED WITH SLEX
分子名称: CALCIUM ION, E-SELECTIN, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside
著者Somers, W.S, Camphausen, R.T.
登録日2000-10-13
公開日2001-10-13
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1.
Cell(Cambridge,Mass.), 103, 2000
4C16
DownloadVisualize
BU of 4c16 by Molmil
E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic antagonist
分子名称: (1R,2R,3S)-3-methylcyclohexane-1,2-diol, (S)-CYCLOHEXYL LACTIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Preston, R.C, Jakob, R.P, Binder, F.P.C, Sager, C.P, Ernst, B, Maier, T.
登録日2013-08-09
公開日2014-08-20
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献E-Selectin Ligand Complexes Adopt an Extended High-Affinity Conformation.
J.Mol.Cell.Biol., 8, 2016
4CSY
DownloadVisualize
BU of 4csy by Molmil
E-selectin lectin, EGF-like and two SCR domains complexed with Sialyl Lewis X
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, E-SELECTIN, ...
著者Preston, R.C, Jakob, R.P, Binder, F.P.C, Sager, C.P, Ernst, B, Maier, T.
登録日2014-03-11
公開日2014-09-24
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献E-Selectin Ligand Complexes Adopt an Extended High-Affinity Conformation.
J.Mol.Cell.Biol., 8, 2016
1ESL
DownloadVisualize
BU of 1esl by Molmil
INSIGHT INTO E-SELECTIN(SLASH)LIGAND INTERACTION FROM THE CRYSTAL STRUCTURE AND MUTAGENESIS OF THE LEC(SLASH)EGF DOMAINS
分子名称: CALCIUM ION, CHLORIDE ION, HUMAN E-SELECTIN
著者Graves, B.J, Crowther, R.L.
登録日1994-06-03
公開日1994-08-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains.
Nature, 367, 1994
6EYK
DownloadVisualize
BU of 6eyk by Molmil
E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic ligand NV355
分子名称: (2~{S})-3-cyclohexyl-2-[(2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-[(1~{R},2~{R},3~{S})-3-methyl-2-[(2~{R},3~{S},4~{R},5~{S},6~{R})-3,4,5-tris(oxidanyl)-6-(trifluoromethyl)oxan-2-yl]oxy-cyclohexyl]oxy-3,5-bis(oxidanyl)oxan-4-yl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Jakob, R.P, Zihlmann, P, Preston, R.C, Varga, N, Ernst, B, Maier, T.
登録日2017-11-13
公開日2018-11-21
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Strengthening an Intramolecular Non-Classical Hydrogen Bond to Get in Shape for Binding.
Angew.Chem.Int.Ed.Engl., 63, 2024
6EYJ
DownloadVisualize
BU of 6eyj by Molmil
E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic ligand NV354
分子名称: (2~{S})-3-cyclohexyl-2-[(2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-3,5-bis(oxidanyl)-6-[(1~{R},2~{R})-2-[(2~{R},3~{S},4~{R},5~{S},6~{R})-3,4,5-tris(oxidanyl)-6-(trifluoromethyl)oxan-2-yl]oxycyclohexyl]oxy-oxan-4-yl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Jakob, R.P, Zihlmann, P, Preston, R.C, Varga, N, Ernst, B, Maier, T.
登録日2017-11-13
公開日2018-11-21
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Strengthening an Intramolecular Non-Classical Hydrogen Bond to Get in Shape for Binding.
Angew.Chem.Int.Ed.Engl., 63, 2024
6EYI
DownloadVisualize
BU of 6eyi by Molmil
E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic ligand BW69669
分子名称: (2~{R})-3-cyclohexyl-2-[(2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-[(1~{R},2~{R})-2-[(2~{S},3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxycyclohexyl]oxy-3,5-bis(oxidanyl)oxan-4-yl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Jakob, R.P, Zihlmann, P, Preston, R.C, Varga, N, Ernst, B, Maier, T.
登録日2017-11-13
公開日2018-11-21
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献E-selectin lectin with different glycomimetic ligands
To Be Published

236963

件を2025-06-04に公開中

PDB statisticsPDBj update infoContact PDBjnumon