6C06
| Mycobacterium tuberculosis RNAP Holo/RbpA/Fidaxomicin | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M. | 登録日 | 2017-12-27 | 公開日 | 2018-03-28 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (5.15 Å) | 主引用文献 | Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts. Elife, 7, 2018
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6C05
| Mycobacterium tuberculosis RNAP Holo/RbpA in relaxed state | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M. | 登録日 | 2017-12-27 | 公開日 | 2018-03-28 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (5.15 Å) | 主引用文献 | Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts. Elife, 7, 2018
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6C9Y
| Cryo-EM structure of E. coli RNAP sigma70 holoenzyme | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Narayanan, A, Vago, F, Li, K, Qayyum, M.Z, Yenool, D, Jiang, W, Murakami, K.S. | 登録日 | 2018-01-29 | 公開日 | 2018-02-28 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.25 Å) | 主引用文献 | Cryo-EM structure ofEscherichia colisigma70RNA polymerase and promoter DNA complex revealed a role of sigma non-conserved region during the open complex formation. J. Biol. Chem., 293, 2018
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6CUX
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6CUU
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6BYU
| X-ray crystal structure of Escherichia coli RNA polymerase (RpoB-H526Y) and ppApp complex | 分子名称: | (5R)-5-(6-amino-9H-purin-9-yl)-2-({[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}methyl)-4-oxo-4,5-dihydrofuran-3-yl trihydrogen diphosphate, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Murakami, K.S, Molodtsov, V. | 登録日 | 2017-12-21 | 公開日 | 2018-01-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structure-function comparisons of (p)ppApp vs (p)ppGpp for Escherichia coli RNA polymerase binding sites and for rrnB P1 promoter regulatory responses in vitro. Biochim. Biophys. Acta, 1861, 2018
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6C04
| Mtb RNAP Holo/RbpA/double fork DNA -closed clamp | 分子名称: | DNA (26-MER), DNA (31-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M. | 登録日 | 2017-12-27 | 公開日 | 2018-03-28 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts. Elife, 7, 2018
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6CA0
| Cryo-EM structure of E. coli RNAP sigma70 open complex | 分子名称: | DNA (35-MER), DNA (45-MER), DNA (5'-D(P*GP*CP*CP*GP*CP*GP*TP*CP*AP*GP*A)-3'), ... | 著者 | Narayanan, A, Vago, F, Li, K, Qayyum, M.Z, Yernool, D, Jiang, W, Murakami, K.S. | 登録日 | 2018-01-29 | 公開日 | 2018-02-28 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (5.75 Å) | 主引用文献 | Cryo-EM structure ofEscherichia colisigma70RNA polymerase and promoter DNA complex revealed a role of sigma non-conserved region during the open complex formation. J. Biol. Chem., 293, 2018
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6DCF
| Crystal structure of a Mycobacterium smegmatis transcription initiation complex with Rifampicin-resistant RNA polymerase and bound to kanglemycin A | 分子名称: | 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ... | 著者 | Lilic, M, Darst, S.A, Campbell, E.A. | 登録日 | 2018-05-06 | 公開日 | 2018-09-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism. Nat Commun, 9, 2018
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6DVC
| Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 6nt spacer | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | 登録日 | 2018-06-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
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7VWY
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7VWZ
| Cryo-EM structure of Rob-dependent transcription activation complex in a unique conformation | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Lin, W, Feng, Y, Shi, J. | 登録日 | 2021-11-12 | 公開日 | 2022-06-08 | 最終更新日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator. Nucleic Acids Res., 50, 2022
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7XL3
| Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with transcription factor SutA (open lobe) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | He, D.W, You, L.L, Zhang, Y. | 登録日 | 2022-04-21 | 公開日 | 2022-07-27 | 最終更新日 | 2022-08-03 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding. Nat Commun, 13, 2022
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7XL4
| Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with transcription factor SutA (closed lobe) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | He, D.W, You, L.L, Zhang, Y. | 登録日 | 2022-04-21 | 公開日 | 2022-07-27 | 最終更新日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | 主引用文献 | Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding. Nat Commun, 13, 2022
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7X76
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7X74
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7X75
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7VF9
| Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | He, D.W, You, L.L, Zhang, Y. | 登録日 | 2021-09-10 | 公開日 | 2022-07-27 | 最終更新日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (4.04 Å) | 主引用文献 | Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding. Nat Commun, 13, 2022
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7VPZ
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7VPD
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7XYA
| The cryo-EM structure of an AlpA-loading complex | 分子名称: | AlpA, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Wen, A, Feng, Y. | 登録日 | 2022-06-01 | 公開日 | 2022-07-20 | 最終更新日 | 2022-08-24 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of AlpA-dependent transcription antitermination. Nucleic Acids Res., 50, 2022
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7XUI
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7YE2
| The cryo-EM structure of C. crescentus GcrA-TACdown | 分子名称: | Cell cycle regulatory protein GcrA, DNA (90-MER)-non template, DNA (90-MER)-template, ... | 著者 | Wu, X.X, Zhang, Y. | 登録日 | 2022-07-05 | 公開日 | 2023-01-18 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM structures of Caulobacter crescentus transcription activation complex with an essential cell cycle regulator GcrA Nucleic Acids Res., 2023
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7YE1
| The cryo-EM structure of C. crescentus GcrA-TACup | 分子名称: | Cell cycle regulatory protein GcrA, DNA (57-MER)-non template, DNA (57-MER)-template, ... | 著者 | Wu, X.X, Zhang, Y. | 登録日 | 2022-07-05 | 公開日 | 2023-01-18 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structures of Caulobacter crescentus transcription activation complex with an essential cell cycle regulator GcrA Nucleic Acids Res., 2023
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7W5W
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