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PDB: 195 件
6XN5
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Structure of the Lactococcus lactis Csm Apo- CRISPR-Cas Complex
分子名称: CRISPR-associated protein Cas10, CRISPR-associated protein Csm3, CRISPR-associated protein Csm4, ...
著者Rai, J, Sridhara, S, Li, H.
登録日2020-07-02
公開日2022-01-12
最終更新日2022-04-13
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structural and biochemical characterization of in vivo assembled Lactococcus lactis CRISPR-Csm complex.
Commun Biol, 5, 2022
6XN3
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Structure of the Lactococcus lactis Csm CTR_4:3 CRISPR-Cas Complex
分子名称: CRISPR-associated protein Cas10, CRISPR-associated protein Csm2, CRISPR-associated protein Csm3, ...
著者Rai, J, Sridhara, S, Li, H.
登録日2020-07-02
公開日2022-01-12
最終更新日2022-04-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural and biochemical characterization of in vivo assembled Lactococcus lactis CRISPR-Csm complex.
Commun Biol, 5, 2022
6XN7
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BU of 6xn7 by Molmil
Structure of the Lactococcus lactis Csm NTR CRISPR-Cas Complex
分子名称: CRISPR-associated protein Cas10, CRISPR-associated protein Csm2, CRISPR-associated protein Csm3, ...
著者Rai, J, Sridhara, S, Li, H.
登録日2020-07-02
公開日2022-01-12
最終更新日2022-04-13
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structural and biochemical characterization of in vivo assembled Lactococcus lactis CRISPR-Csm complex.
Commun Biol, 5, 2022
6YXA
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Structure of the bifunctional Rel enzyme from B. subtilis
分子名称: GTP pyrophosphokinase, MANGANESE (II) ION
著者Pausch, P, Bange, G.
登録日2020-04-30
公開日2020-09-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.95 Å)
主引用文献Structural Basis for Regulation of the Opposing (p)ppGpp Synthetase and Hydrolase within the Stringent Response Orchestrator Rel.
Cell Rep, 32, 2020
5AO0
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BU of 5ao0 by Molmil
Crystal structure of human SAMHD1 (amino acid residues 41-583) bound to ddGTP
分子名称: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, FE (III) ION, ...
著者Schwefel, D, Taylor, I.A.
登録日2015-09-09
公開日2015-10-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.731 Å)
主引用文献Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction.
Plos Pathog., 11, 2015
6MUR
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BU of 6mur by Molmil
Cryo-EM structure of Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system
分子名称: RNA (27-MER), RNA (5'-R(P*GP*CP*AP*AP*AP*CP*CP*GP*CP*CP*UP*CP*UP*GP*CP*CP*CP*GP*C)-3'), Uncharacterized protein, ...
著者Jia, N, Wang, C, Eng, E.T, Patel, D.J.
登録日2018-10-23
公開日2018-12-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
6MUT
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BU of 6mut by Molmil
Cryo-EM structure of ternary Csm-crRNA-target RNA with anti-tag sequence complex in type III-A CRISPR-Cas system
分子名称: RNA (5'-R(*GP*UP*GP*GP*AP*AP*AP*GP*GP*CP*GP*GP*GP*CP*AP*GP*AP*GP*GP*C)-3'), RNA (5'-R(P*CP*CP*UP*CP*UP*GP*CP*CP*CP*GP*CP*CP*UP*UP*UP*CP*CP*AP*C)-3'), Uncharacterized protein Csm1, ...
著者Jia, N, Wang, C, Eng, E.T, Patel, D.J.
登録日2018-10-23
公開日2018-12-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
6MUS
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Cryo-EM structure of larger Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system
分子名称: RNA (25-MER), RNA (33-MER), Uncharacterized protein Csm1, ...
著者Jia, N, Wang, C, Eng, E.T.
登録日2018-10-23
公開日2018-12-12
最終更新日2019-01-30
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
6NUD
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Small conformation of ssRNA-bound CRISPR_Csm complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms protein Csm2, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), ...
著者Zhang, K, Pintilie, G, Li, S, Zhu, Y, Chiu, W, Huang, Z.
登録日2019-01-31
公開日2019-03-13
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry.
Cell Res., 29, 2019
6MUA
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Crystal structure of Csm1-Csm4 subcomplex in the type III-A CRISPR-Csm interference complex
分子名称: Uncharacterized protein Csm1, Uncharacterized protein Csm4
著者Jia, N, Patel, D.J.
登録日2018-10-22
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
6NUE
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BU of 6nue by Molmil
Small conformation of apo CRISPR_Csm complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms protein Csm2, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), ...
著者Zhang, K, Pintilie, G, Li, S, Zhu, Y, Chiu, W, Huang, Z.
登録日2019-01-31
公開日2019-03-13
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry.
Cell Res., 29, 2019
6MUU
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Cryo-EM structure of Csm-crRNA binary complex in type III-A CRISPR-Cas system
分子名称: RNA (25-MER), Uncharacterized protein Csm1, Uncharacterized protein Csm2, ...
著者Jia, N, Wang, C, Eng, E.T, Patel, D.J.
登録日2018-10-23
公開日2018-12-19
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
7V01
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BU of 7v01 by Molmil
Staphylococcus epidermidis RP62a CRISPR short effector complex with self RNA target and ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm2, ...
著者Smith, E.M, Ferrell, S.H, Tokars, V.L, Mondragon, A.
登録日2022-05-09
公開日2022-07-06
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Structures of an active type III-A CRISPR effector complex.
Structure, 30, 2022
7UZY
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BU of 7uzy by Molmil
Staphylococcus epidermidis RP62A CRISPR effector complex with non-self target RNA 2
分子名称: CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm2, CRISPR system Cms protein Csm4, ...
著者Smith, E.M, Ferrell, S.H, Tokars, V.L, Mondragon, A.
登録日2022-05-09
公開日2022-07-06
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (4.05 Å)
主引用文献Structures of an active type III-A CRISPR effector complex.
Structure, 30, 2022
7V02
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BU of 7v02 by Molmil
Staphylococcus epidermidis RP62A CRISPR short effector complex
分子名称: CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm2, CRISPR system Cms protein Csm4, ...
著者Smith, E.M, Ferrell, S.H, Tokars, V.L, Mondragon, A.
登録日2022-05-09
公開日2022-07-06
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (4.97 Å)
主引用文献Structures of an active type III-A CRISPR effector complex.
Structure, 30, 2022
7UZZ
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Staphylococcus epidermidis RP62a CRISPR tall effector complex
分子名称: CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm2, CRISPR system Cms protein Csm4, ...
著者Smith, E.M, Ferrell, S.H, Tokars, V.L, Mondragon, A.
登録日2022-05-09
公開日2022-07-06
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (4.45 Å)
主引用文献Structures of an active type III-A CRISPR effector complex.
Structure, 30, 2022
7UZW
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Staphylococcus epidermidis RP62a CRISPR effector subcomplex
分子名称: CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm4, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), ...
著者Smith, E.M, Ferrell, S.H, Tokars, V.L, Mondragon, A.
登録日2022-05-09
公開日2022-07-06
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Structures of an active type III-A CRISPR effector complex.
Structure, 30, 2022
7UZX
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BU of 7uzx by Molmil
Staphylococcus epidermidis RP62a CRISPR effector subcomplex with non-self target RNA bound
分子名称: CRISPR non-self RNA target, CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm4, ...
著者Smith, E.M, Ferrell, S.H, Tokars, V.L, Mondragon, A.
登録日2022-05-09
公開日2022-07-06
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Structures of an active type III-A CRISPR effector complex.
Structure, 30, 2022
7V00
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BU of 7v00 by Molmil
Staphylococcus epidermidis RP62a CRISPR tall effector complex with bound ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm2, ...
著者Smith, E.M, Ferrell, S.H, Tokars, V.L, Mondragon, A.
登録日2022-05-09
公開日2022-07-06
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (3.87 Å)
主引用文献Structures of an active type III-A CRISPR effector complex.
Structure, 30, 2022
7UJN
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BU of 7ujn by Molmil
Structure of Human SAMHD1 with Non-Hydrolysable dGTP Analog
分子名称: 2'-deoxyguanosine-5'-O-(1-thiotriphosphate), Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
著者Huynh, K.W, Ammirati, M, Han, S.
登録日2022-03-31
公開日2022-07-20
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Phosphorylation of SAMHD1 Thr592 increases C-terminal domain dynamics, tetramer dissociation and ssDNA binding kinetics.
Nucleic Acids Res., 50, 2022
2O6I
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BU of 2o6i by Molmil
Structure of an Enterococcus Faecalis HD Domain Phosphohydrolase
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, HD domain protein, ...
著者Vorontsov, I.I, Minasov, G, Shuvalova, L, Brunzelle, J.S, Moy, S, Collart, F.R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG)
登録日2006-12-07
公開日2006-12-19
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Characterization of the deoxynucleotide triphosphate triphosphohydrolase (dNTPase) activity of the EF1143 protein from Enterococcus faecalis and crystal structure of the activator-substrate complex.
J.Biol.Chem., 286, 2011
2Q14
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Crystal structure of Phosphohydrolase (BT4208) from Bacteroides thetaiotaomicron VPI-5482 at 2.20 A resolution
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2007-05-23
公開日2007-06-12
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Phosphohydrolase (BT4208) from Bacteroides thetaiotaomicron VPI-5482 at 2.20 A resolution
To be published
7U65
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Structure of E. coli dGTPase bound to T7 bacteriophage protein Gp1.2
分子名称: Deoxyguanosinetriphosphate triphosphohydrolase, Inhibitor of dGTPase
著者Klemm, B.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M.
登録日2022-03-03
公開日2022-08-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase.
Proc.Natl.Acad.Sci.USA, 119, 2022
7U67
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Structure of E. coli dGTPase bound to T7 bacteriophage protein Gp1.2 and GTP
分子名称: Deoxyguanosinetriphosphate triphosphohydrolase, GUANOSINE-5'-TRIPHOSPHATE, Inhibitor of dGTPase, ...
著者Klemm, B.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M.
登録日2022-03-03
公開日2022-08-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase.
Proc.Natl.Acad.Sci.USA, 119, 2022
7U66
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Structure of E. coli dGTPase bound to T7 bacteriophage protein Gp1.2 and dGTP
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxyguanosinetriphosphate triphosphohydrolase, Inhibitor of dGTPase, ...
著者Klemm, B.P, Dillard, L.B, Borgnia, M.J, Schaaper, R.M.
登録日2022-03-03
公開日2022-08-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase.
Proc.Natl.Acad.Sci.USA, 119, 2022

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件を2024-07-10に公開中

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