7ALK
| Structure of Drosophila C2-DSL-EGF1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neurogenic locus protein delta, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Suckling, R, Johnson, S, Lea, S.M. | 登録日 | 2020-10-06 | 公開日 | 2021-08-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The conserved C2 phospholipid-binding domain in Delta contributes to robust Notch signalling. Embo Rep., 22, 2021
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7ALT
| Structure of Drosophila Serrate C2-DSL-EGF1-EGF2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Suckling, R, Johnson, S, Lea, S.M. | 登録日 | 2020-10-07 | 公開日 | 2021-08-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | The conserved C2 phospholipid-binding domain in Delta contributes to robust Notch signalling. Embo Rep., 22, 2021
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5MWF
| Human Jagged2 C2-EGF2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | 著者 | Suckling, R.J, Handford, P.A, Lea, S.M. | 登録日 | 2017-01-18 | 公開日 | 2017-06-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands. EMBO J., 36, 2017
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5MW5
| Human Jagged2 C2-EGF2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Protein jagged-2 | 著者 | Suckling, R.J, Handford, P.A, Lea, S.M. | 登録日 | 2017-01-18 | 公開日 | 2017-06-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands. EMBO J., 36, 2017
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5BO1
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2VJ2
| Human Jagged-1, domains DSL and EGFs1-3 | 分子名称: | D-MALATE, JAGGED-1 | 著者 | Johnson, S, Cordle, J, Tay, J.Z, Roversi, P, Handford, P.A, Lea, S.M. | 登録日 | 2007-12-06 | 公開日 | 2008-07-29 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition. Nat.Struct.Mol.Biol., 15, 2008
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5UK5
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4XBM
| X-ray crystal structure of Notch ligand Delta-like 1 | 分子名称: | Delta-like protein 1, alpha-L-fucopyranose | 著者 | Kershaw, N.J, Burgess, A.W, Church, N.L, Luo, C.S, Adam, T.E. | 登録日 | 2014-12-17 | 公開日 | 2015-03-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Notch ligand delta-like1: X-ray crystal structure and binding affinity. Biochem.J., 468, 2015
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4XL1
| Complex of Notch1 (EGF11-13) bound to Delta-like 4 (N-EGF1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Luca, V.C, Jude, K.M, Garcia, K.C. | 登録日 | 2015-01-13 | 公開日 | 2015-03-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural biology. Structural basis for Notch1 engagement of Delta-like 4. Science, 347, 2015
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4XLW
| Complex of Notch1 (EGF11-13) bound to Delta-like 4 (N-EGF2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Delta-like protein, ... | 著者 | Luca, V.C, Jude, K.M, Garcia, K.C. | 登録日 | 2015-01-13 | 公開日 | 2015-03-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.39 Å) | 主引用文献 | Structural biology. Structural basis for Notch1 engagement of Delta-like 4. Science, 347, 2015
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4CBZ
| Notch ligand, Jagged-1, contains an N-terminal C2 domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN JAGGED-1, alpha-L-fucopyranose | 著者 | Chilakuri, C.R, Sheppard, D, Ilagan, M.X.G, Holt, L.R, Abbott, F, Liang, S, Kopan, R, Handford, P.A, Lea, S.M. | 登録日 | 2013-10-17 | 公開日 | 2013-11-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Analysis Uncovers Lipid-Binding Properties of Notch Ligands Cell Rep., 5, 2013
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4CC1
| Notch ligand, Jagged-1, contains an N-terminal C2 domain | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Chilakuri, C.R, Sheppard, D, Ilagan, M.X.G, Holt, L.R, Abbott, F, Liang, S, Kopan, R, Handford, P.A, Lea, S.M. | 登録日 | 2013-10-17 | 公開日 | 2013-11-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Structural Analysis Uncovers Lipid-Binding Properties of Notch Ligands Cell Rep., 5, 2013
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4CC0
| Notch ligand, Jagged-1, contains an N-terminal C2 domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PROTEIN JAGGED-1, ... | 著者 | Chilakuri, C.R, Sheppard, D, Ilagan, M.X.G, Holt, L.R, Abbott, F, Liang, S, Kopan, R, Handford, P.A, Lea, S.M. | 登録日 | 2013-10-17 | 公開日 | 2013-11-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Structural Analysis Uncovers Lipid-Binding Properties of Notch Ligands Cell Rep., 5, 2013
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5MVX
| Human DLL4 C2-EGF3 | 分子名称: | Delta-like protein 4, alpha-L-fucopyranose | 著者 | Suckling, R.J, Handford, P.A, Lea, S.M. | 登録日 | 2017-01-17 | 公開日 | 2017-06-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands. EMBO J., 36, 2017
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5MW7
| Human Jagged2 C2-EGF3 | 分子名称: | Protein jagged-2, alpha-L-fucopyranose | 著者 | Suckling, R.J, Handford, P.A, Lea, S.M. | 登録日 | 2017-01-18 | 公開日 | 2017-06-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands. EMBO J., 36, 2017
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