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PDB: 868 件
4YXA
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Complex of SpaO(SPOA1,2 SeMet) and OrgB(APAR)::T4lysozyme fusion protein
分子名称: Oxygen-regulated invasion protein OrgB,Endolysin, Surface presentation of antigens protein SpaO
著者Notti, R.Q, Stebbins, C.E.
登録日2015-03-22
公開日2015-06-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A common assembly module in injectisome and flagellar type III secretion sorting platforms.
Nat Commun, 6, 2015
6WSK
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BU of 6wsk by Molmil
Crystal Structure of the Cannabinoid Receptor 1 Interacting Protein 1a (CRIP1a)
分子名称: Endolysin,CB1 cannabinoid receptor-interacting protein 1 fusion
著者Booth, W.T, Howlett, A.C, Lowther, W.T.
登録日2020-05-01
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Cannabinoid receptor interacting protein 1a interacts with myristoylated G alpha i N terminus via a unique gapped beta-barrel structure.
J.Biol.Chem., 297, 2021
6XYR
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BU of 6xyr by Molmil
Structure of the T4Lnano fusion protein
分子名称: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
著者Benoit, R.M, Bierig, T, Collu, C, Engilberge, S, Olieric, V.
登録日2020-01-31
公開日2020-12-09
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.079 Å)
主引用文献Chimeric single alpha-helical domains as rigid fusion protein connections for protein nanotechnology and structural biology.
Structure, 30, 2022
6XOQ
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BU of 6xoq by Molmil
DCN1 covalently bound to inhibitor 4
分子名称: (2E)-N-[(2S)-2-cyclohexyl-2-({N-propanoyl-3-[6-(propan-2-yl)-1,3-benzothiazol-2-yl]-L-alanyl}amino)ethyl]-4-(morpholin-4-yl)but-2-enamide, Lysozyme, DCN1-like protein 1 chimera
著者Stuckey, J.A.
登録日2020-07-07
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity.
Nat Commun, 12, 2021
6XOM
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DCN1 bound to 8
分子名称: (2R)-N-[(2S)-2-cyclohexyl-2-({N-propanoyl-3-[6-(propan-2-yl)-1,3-benzothiazol-2-yl]-L-alanyl}amino)ethyl]-2-methyl-4-(morpholin-4-yl)butanamide, 1,2-ETHANEDIOL, Lysozyme, ...
著者Stuckey, J.A.
登録日2020-07-07
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity.
Nat Commun, 12, 2021
6XON
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BU of 6xon by Molmil
DCN1 bound to inhibitor 9
分子名称: (2S)-N-[(2S)-2-cyclohexyl-2-({N-propanoyl-3-[6-(propan-2-yl)-1,3-benzothiazol-2-yl]-L-alanyl}amino)ethyl]-4-(dimethylamino)-2-methylbutanamide, Lysozyme DCN1-like protein 1 chimera
著者Stuckey, J.A.
登録日2020-07-07
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity.
Nat Commun, 12, 2021
6XOO
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BU of 6xoo by Molmil
DCN1 bound to DI-1859
分子名称: Lysozyme, DCN1-like protein 1 chimera, N-{(1S)-1-cyclohexyl-2-[(2-methylpropanoyl)amino]ethyl}-N~2~-propanoyl-3-[6-(propan-2-yl)-1,3-benzothiazol-2-yl]-L-alaninamide
著者Stuckey, J.A.
登録日2020-07-07
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity.
Nat Commun, 12, 2021
6XOL
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BU of 6xol by Molmil
DCN1 bound to DI-1548
分子名称: Lysozyme, DCN1-like protein 1 chimera, N-{(1S)-1-cyclohexyl-2-[(2-methylpropanoyl)amino]ethyl}-N~2~-propanoyl-3-[6-(propan-2-yl)-1,3-benzothiazol-2-yl]-L-alaninamide
著者Stuckey, J.A.
登録日2020-07-07
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity.
Nat Commun, 12, 2021
6XOP
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BU of 6xop by Molmil
DCN1 bound to inhibitor 10
分子名称: Lysozyme, DCN1-like protein 1 chimera, N-[(1S)-1-cyclohexyl-2-{[(2S)-3-(1H-imidazol-1-yl)-2-methylpropanoyl]amino}ethyl]-N~2~-propanoyl-3-[6-(propan-2-yl)-1,3-benzothiazol-2-yl]-L-alaninamide
著者Stuckey, J.A.
登録日2020-07-07
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity.
Nat Commun, 12, 2021
6XMV
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BU of 6xmv by Molmil
The crystal structure of Neisseria gonorrhoeae DolP (NGO1985)
分子名称: CHLORIDE ION, Hemolysin,Endolysin
著者Li, J, Peterson Brown, L.E, Reed, R.W, Wierzbicki, I.H, Sikora, A.E, Korotkov, K.V.
登録日2020-06-30
公開日2021-11-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The structure and function of a new component of Bam complex in Neisseria
To Be Published
5EWX
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BU of 5ewx by Molmil
Fusion protein of T4 lysozyme and B4 domain of protein A from staphylococcal aureus with chemical cross-linker EY-CBS
分子名称: 2,2'-ethyne-1,2-diylbis{5-[(chloroacetyl)amino]benzenesulfonic acid}, Endolysin,Immunoglobulin G-binding protein A,Endolysin
著者Jeong, W.H, Lee, H, Song, D.H, Lee, J.O.
登録日2015-11-22
公開日2016-03-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker.
Nat Commun, 7, 2016
4EXM
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BU of 4exm by Molmil
The crystal structure of an engineered phage lysin containing the binding domain of pesticin and the killing domain of T4-lysozyme
分子名称: Pesticin, Lysozyme Chimera
著者Seddiki, N, Noinaj, N, Fairman, J.W, Lukacik, P, Barnard, T.J, Buchanan, S.K.
登録日2012-04-30
公開日2012-06-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural engineering of a phage lysin that targets Gram-negative pathogens.
Proc.Natl.Acad.Sci.USA, 109, 2012
4EPI
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BU of 4epi by Molmil
The crystal structure of pesticin-T4 lysozyme hybrid stabilized by engineered disulfide bonds
分子名称: Pesticin, Lysozyme Chimera, SODIUM ION, ...
著者Seddiki, N, Fairman, J.W, Noinaj, N, Lukacik, P, Barnard, T, Buchanan, S.K.
登録日2012-04-17
公開日2012-06-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural engineering of a phage lysin that targets Gram-negative pathogens.
Proc.Natl.Acad.Sci.USA, 109, 2012
4IAP
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BU of 4iap by Molmil
Crystal structure of PH domain of Osh3 from Saccharomyces cerevisiae
分子名称: Oxysterol-binding protein homolog 3,Endolysin,Oxysterol-binding protein homolog 3, SULFATE ION
著者Tong, J, Im, Y.J.
登録日2012-12-07
公開日2013-07-31
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins
Structure, 21, 2013
6LB8
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BU of 6lb8 by Molmil
Crystal structure of the Ca2+-free T4L-MICU1-MICU2 complex
分子名称: Calcium uptake protein 2, mitochondrial, Endolysin,Calcium uptake protein 1
著者Wu, W, Shen, Q, Zheng, J, Jia, Z.
登録日2019-11-13
公開日2020-07-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.283 Å)
主引用文献The structure of the MICU1-MICU2 complex unveils the regulation of the mitochondrial calcium uniporter.
Embo J., 39, 2020
2QAR
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BU of 2qar by Molmil
Structure of the 2TEL crystallization module fused to T4 lysozyme with a helical linker.
分子名称: AMMONIUM ION, E80-TELSAM domain, Lysozyme, ...
著者Nauli, S, Bowie, J.U.
登録日2007-06-15
公開日2008-01-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Polymer-driven crystallization.
Protein Sci., 16, 2007
2QB0
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BU of 2qb0 by Molmil
Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.
分子名称: MANGANESE (II) ION, Transcription factor ETV6, Transcription factor ETV6,Endolysin
著者Nauli, S, Bowie, J.U.
登録日2007-06-15
公開日2008-10-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Polymer-driven crystallization.
Protein Sci., 16, 2007
5YQR
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BU of 5yqr by Molmil
Crystal structure of the PH-like domain of Lam6
分子名称: Endolysin/Membrane-anchored lipid-binding protein LAM6 fusion protein, NONAETHYLENE GLYCOL
著者Tong, J, Im, Y.J.
登録日2017-11-07
公開日2018-01-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Structural basis of sterol recognition and nonvesicular transport by lipid transfer proteins anchored at membrane contact sites
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6AJH
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BU of 6ajh by Molmil
Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with AU1235
分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 1-(2-adamantyl)-3-[2,3,4-tris(fluoranyl)phenyl]urea, Drug exporters of the RND superfamily-like protein,Endolysin, ...
著者Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H.
登録日2018-08-27
公開日2018-12-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.818 Å)
主引用文献Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target.
Cell, 176, 2019
6AJI
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BU of 6aji by Molmil
Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with Rimonabant
分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide, Drug exporters of the RND superfamily-like protein,Endolysin, ...
著者Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H.
登録日2018-08-27
公開日2018-12-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target.
Cell, 176, 2019
6AJF
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Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis
分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Drug exporters of the RND superfamily-like protein,Endolysin, alpha-D-glucopyranosyl 6-O-dodecyl-alpha-D-glucopyranoside
著者Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H.
登録日2018-08-27
公開日2018-12-26
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.698 Å)
主引用文献Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target.
Cell, 176, 2019
6BG5
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BU of 6bg5 by Molmil
Structure of 1-(benzo[d][1,3]dioxol-5-ylmethyl)-1-(1-propylpiperidin-4-yl)-3-(3-(trifluoromethyl)phenyl)urea bound to DCN1
分子名称: Endolysin, DCN1-like protein 1 chimera, N-[(2H-1,3-benzodioxol-5-yl)methyl]-N-(1-propylpiperidin-4-yl)-N'-[3-(trifluoromethyl)phenyl]urea
著者Guy, R.K, Schulman, B.A, Scott, D.C, Hammill, J.T.
登録日2017-10-27
公開日2018-09-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Piperidinyl Ureas Chemically Control Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation.
J. Med. Chem., 61, 2018
6A9E
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BU of 6a9e by Molmil
Crystal structure of the N-terminal domain of Atg2
分子名称: Endolysin,Autophagy-related protein 2
著者Osawa, T, Noda, N.N.
登録日2018-07-13
公開日2019-03-20
最終更新日2019-04-17
実験手法X-RAY DIFFRACTION (3.205 Å)
主引用文献Atg2 mediates direct lipid transfer between membranes for autophagosome formation.
Nat. Struct. Mol. Biol., 26, 2019
6A9J
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BU of 6a9j by Molmil
Crystal structure of the PE-bound N-terminal domain of Atg2
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Endolysin,Autophagy-related protein 2
著者Osawa, T, Noda, N.N.
登録日2018-07-13
公開日2019-03-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Atg2 mediates direct lipid transfer between membranes for autophagosome formation.
Nat. Struct. Mol. Biol., 26, 2019
6AJG
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BU of 6ajg by Molmil
Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with SQ109
分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, DODECYL-BETA-D-MALTOSIDE, Drug exporters of the RND superfamily-like protein,Endolysin, ...
著者Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H.
登録日2018-08-27
公開日2018-12-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target.
Cell, 176, 2019

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