6DGM
 
 | | Streptococcus pyogenes phosphoglycerol transferase GacH in complex with sn-glycerol-1-phosphate | | 分子名称: | CALCIUM ION, MANGANESE (II) ION, Phosphoglycerol transferase GacH, ... | | 著者 | Edgar, R.J, Korotkova, N, Korotkov, K.V. | | 登録日 | 2018-05-17 | | 公開日 | 2018-06-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides.
Nat.Chem.Biol., 15, 2019
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3LXQ
 | | The Crystal Structure of a Protein in the Alkaline Phosphatase Superfamily from Vibrio parahaemolyticus to 1.95A | | 分子名称: | CHLORIDE ION, Uncharacterized protein VP1736 | | 著者 | Stein, A.J, Weger, A, Duggan, E, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2010-02-25 | | 公開日 | 2010-03-09 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | The Crystal Structure of a Protein in the Alkaline Phosphatase Superfamily from Vibrio parahaemolyticus to 1.95A
To be Published
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5AJ9
 | | G7 mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ARYLSULFATASE, CALCIUM ION, ... | | 著者 | Miton, C.M, Fischer, G, Jonas, S, Mohammed, M.F, Loo, B.v, Kintses, B, Hyvonen, M, Tokuriki, N, Hollfelder, F. | | 登録日 | 2015-02-20 | | 公開日 | 2016-03-16 | | 最終更新日 | 2019-04-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6LI6
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5LRN
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6LI4
 | | Crystal structure of MCR-1-S | | 分子名称: | Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION | | 著者 | Zhang, Q, Wang, M, Sun, H. | | 登録日 | 2019-12-10 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin.
Nat Commun, 11, 2020
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6LI5
 | | Crystal structure of apo-MCR-1-S | | 分子名称: | Probable phosphatidylethanolamine transferase Mcr-1 | | 著者 | Zhang, Q, Wang, M, Sun, H. | | 登録日 | 2019-12-10 | | 公開日 | 2020-09-16 | | 最終更新日 | 2020-10-28 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin.
Nat Commun, 11, 2020
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5MX9
 | | High resolution crystal structure of the MCR-2 catalytic domain | | 分子名称: | GLYCEROL, Phosphatidylethanolamine transferase Mcr-2, ZINC ION | | 著者 | Hinchliffe, P, Coates, K, Walsh, T.R, Spencer, J. | | 登録日 | 2017-01-22 | | 公開日 | 2017-08-09 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | | 主引用文献 | 1.12 angstrom resolution crystal structure of the catalytic domain of the plasmid-mediated colistin resistance determinant MCR-2.
Acta Crystallogr F Struct Biol Commun, 73, 2017
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6SUT
 | | Crystal structure of phosphothreonine MCR-2 | | 分子名称: | BROMIDE ION, GLYCEROL, Putative integral membrane protein, ... | | 著者 | Hinchliffe, P, Spencer, J. | | 登録日 | 2019-09-16 | | 公開日 | 2020-06-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Resistance to the "last resort" antibiotic colistin: a single-zinc mechanism for phosphointermediate formation in MCR enzymes.
Chem.Commun.(Camb.), 56, 2020
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5LRM
 | | Structure of di-zinc MCR-1 in P41212 space group | | 分子名称: | GLYCEROL, ZINC ION, phosphatidylethanolamine transferase Mcr-1 | | 著者 | Hinchliffe, P, Spencer, J. | | 登録日 | 2016-08-19 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Insights into the Mechanistic Basis of Plasmid-Mediated Colistin Resistance from Crystal Structures of the Catalytic Domain of MCR-1.
Sci Rep, 7, 2017
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4KAY
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6IOZ
 | | Structural insights of idursulfase beta | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kim, H, Kim, D, Hong, J, Lee, K, Seo, J, Oh, B.H. | | 登録日 | 2018-11-01 | | 公開日 | 2018-11-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural insights of idursulfase beta
To Be Published
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7OZC
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7P26
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5K4P
 | | Catalytic Domain of MCR-1 phosphoethanolamine transferase | | 分子名称: | Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION, sorbitol | | 著者 | Stojanoski, V, Palzkill, T, Prasad, B.V.V, Sankaran, B. | | 登録日 | 2016-05-21 | | 公開日 | 2016-08-31 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.318 Å) | | 主引用文献 | Structure of the catalytic domain of the colistin resistance enzyme MCR-1.
Bmc Biol., 14, 2016
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4KAV
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4CYS
 | | G6 mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa, in complex with Phenylphosphonic acid | | 分子名称: | AMMONIUM ION, ARYLSULFATASE, CALCIUM ION, ... | | 著者 | Miton, C.M, Jonas, S, Mohammed, M.F, Fischer, G, Loo, B.v, Kintses, B, Hyvonen, M, Tokuriki, N, Hollfelder, F. | | 登録日 | 2014-04-14 | | 公開日 | 2015-04-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4CXU
 | | G4 mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa, in complex with 3-Br-Phenolphenylphosphonate | | 分子名称: | 3-bromophenyl hydrogen (S)-phenylphosphonate, ARYLSULFATASE, CALCIUM ION | | 著者 | Miton, C.M, Jonas, S, Mohammed, M.F, Fischer, G, Loo, B.v, Kintses, B, Hyvonen, M, Tokuriki, N, Hollfelder, F. | | 登録日 | 2014-04-08 | | 公開日 | 2015-04-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4CXK
 | | G9 mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa | | 分子名称: | ARYLSULFATASE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Miton, C.M, Jonas, S, Mohammed, M.F, Fischer, G, Loo, B.v, Kintses, B, Hyvonen, M, Tokuriki, N, Hollfelder, F. | | 登録日 | 2014-04-07 | | 公開日 | 2015-04-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4CXS
 | | G4 mutant of PAS, arylsulfatase from Pseudomonas aeruginosa, in complex with Phenylphosphonic acid | | 分子名称: | ARYLSULFATASE, CALCIUM ION, SULFATE ION, ... | | 著者 | Miton, C.M, Jonas, S, Mohammed, M.F, Fischer, G, Loo, B.v, Kintses, B, Hyvonen, M, Tokuriki, N, Hollfelder, F. | | 登録日 | 2014-04-08 | | 公開日 | 2015-05-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4CYR
 | | G4 mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa | | 分子名称: | ARYLSULFATASE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Miton, C.M, Jonas, S, Mohammed, M.F, Fischer, G, Loo, B.v, Kintses, B, Hyvonen, M, Tokuriki, N, Hollfelder, F. | | 登録日 | 2014-04-14 | | 公開日 | 2015-04-29 | | 最終更新日 | 2019-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6A7W
 | | Structure of a catalytic domain of the colistin resistance enzyme | | 分子名称: | Putative integral membrane protein, ZINC ION | | 著者 | Wang, X.D, Chai, Y, Qi, J.X, Gao, G.F. | | 登録日 | 2018-07-04 | | 公開日 | 2018-11-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.988 Å) | | 主引用文献 | Structural and functional insights into MCR-2 mediated colistin resistance.
Sci China Life Sci, 61, 2018
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6A82
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6VAT
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7WAA
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