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PDB: 256 件

4UR7
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Crystal structure of keto-deoxy-D-galactarate dehydratase complexed with pyruvate
分子名称: FORMIC ACID, GLYCEROL, KETO-DEOXY-D-GALACTARATE DEHYDRATASE
著者Taberman, H, Parkkinen, T, Hakulinen, N, Rouvinen, J.
登録日2014-06-26
公開日2014-12-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.499 Å)
主引用文献Structure and Function of a Decarboxylating Agrobacterium Tumefaciens Keto-Deoxy-D-Galactarate Dehydratase.
Biochemistry, 53, 2014
4UXD
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2-keto 3-deoxygluconate aldolase from Picrophilus torridus
分子名称: 1,2-ETHANEDIOL, 2-DEHYDRO-3-DEOXY-D-GLUCONATE/2-DEHYDRO-3-DEOXY-PHOSPHOGLUCONATE ALDOLASE, DI(HYDROXYETHYL)ETHER, ...
著者Priftis, A, Zaitsev, V, Reher, M, Johnsen, U, Danson, M.J, Taylor, G.L, Schoenheit, P, Crennell, S.J.
登録日2014-08-22
公開日2015-09-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Insights into the Substrate Specificity of Archaeal Entner-Doudoroff Aldolases: The Structures of Picrophilus torridus 2-Keto-3-deoxygluconate Aldolase and Sulfolobus solfataricus 2-Keto-3-deoxy-6-phosphogluconate Aldolase in Complex with 2-Keto-3-deoxy-6-phosphogluconate.
Biochemistry, 57, 2018
7LCF
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Dihydrodipicolinate synthase (DHDPS) from C.jejuni, with pyruvate bound in the active site and L-lysine bound at the allosteric site in C121 space group
分子名称: 4-hydroxy-tetrahydrodipicolinate synthase, LYSINE, MAGNESIUM ION
著者Saran, S, Sanders, D.A.R.
登録日2021-01-10
公開日2022-01-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献B-factors: L- lysine and R, R- bisLysine allosterically inhibit Cj. DHDPS Enzyme by decreasing its protein dynamics
To Be Published
4UR8
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Crystal structure of keto-deoxy-D-galactarate dehydratase complexed with 2-oxoadipic acid
分子名称: 2-OXOADIPIC ACID, FORMIC ACID, KETO-DEOXY-D-GALACTARATE DEHYDRATASE
著者Taberman, H, Parkkinen, T, Hakulinen, N, Rouvinen, J.
登録日2014-06-26
公開日2014-12-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.097 Å)
主引用文献Structure and Function of a Decarboxylating Agrobacterium Tumefaciens Keto-Deoxy-D-Galactarate Dehydratase.
Biochemistry, 53, 2014
7LBD
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Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59K mutant with pyruvate bound in the active site in C2221 space group
分子名称: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ...
著者Saran, S, Yazdi, M.M, Sanders, D.A.R.
登録日2021-01-07
公開日2022-01-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Reversing the roles of a crucial hydrogen-bonding pair: a lysine-insensitive mutant of Campylobacter jejuni dihydrodipicolinate synthase, H59K, binds histidine in its allosteric site
To Be Published
4WOQ
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Crystal Structures of CdNal from Clostridium difficile in complex with ketobutyric
分子名称: 2-KETOBUTYRIC ACID, N-acetylneuraminate lyase
著者Liu, W.D, Guo, R.T, Cui, Y.F, Chen, X, Wu, Q.Q, Zhu, D.M.
登録日2014-10-16
公開日2015-10-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structures of CdNal from Clostridium difficile in complex with ketobutyric
to be published
7M06
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Dihydrodipicolinate synthase (DHDPS) from C.jejuni, Y110F mutant with R,R-bislysine bound at the allosteric site at 2.7 Angstrom
分子名称: (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ...
著者Saran, S, Sanders, D.A.R.
登録日2021-03-10
公開日2022-03-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献B-FACTOR ANALYSIS SUGGEST THAT L-LYSINE AND R, R-BISLYSINE ALLOSTERICALLY INHIBIT Cj.DHDPS ENZYME BY DECREASING PROTEIN DYNAMICS
To Be Published
4WOZ
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Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine
分子名称: 2-(ACETYLAMINO)-2-DEOXY-D-MANNOSE, N-acetylneuraminate lyase
著者Liu, W.D, Guo, R.T, Cui, Y.F, Chen, X, Wu, Q.Q, Zhu, D.M.
登録日2014-10-17
公開日2015-10-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine
to be published
7MJF
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Crystal structure of Candidatus Liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site
分子名称: (4R)-4-oxidanyl-2-oxidanylidene-heptanedioic acid, (4S)-4-hydroxy-2-oxoheptanedioic acid, 4-hydroxy-tetrahydrodipicolinate synthase
著者Gilkes, J, Frampton, R.A, Board, A.J, Sheen, C.R, Smith, G.R, Dobson, R.C.J.
登録日2021-04-20
公開日2021-07-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Candidatus Liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site
To Be Published
7MDS
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Crystal structure of AtDHDPS1 in complex with MBDTA-2
分子名称: 4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic, CHLORIDE ION, ...
著者Hall, C.J, Soares da Costa, T.P, Panjikar, S.
登録日2021-04-06
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.295 Å)
主引用文献Towards novel herbicide modes of action by inhibiting lysine biosynthesis in plants.
Elife, 10, 2021
8U90
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Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (Apo, hexagonal form)
分子名称: CHLORIDE ION, GLYCEROL, IODIDE ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-09-18
公開日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (Apo, hexagonal form)
To be published
8U92
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Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate bound, Orthorhombic P form)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, GLYCEROL, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-09-18
公開日2023-09-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate bound, Orthorhombic P form)
To be published
8U93
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Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (PEG bound)
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, CHLORIDE ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-09-18
公開日2023-09-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (PEG bound)
To be published
8U8W
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Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate and halides bound)
分子名称: CHLORIDE ION, GLYCEROL, IODIDE ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-09-18
公開日2023-09-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate and halides bound)
To be published
8U91
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Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (Apo, Orthorhombic P form)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, N-acetylneuraminate lyase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-09-18
公開日2023-09-27
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (Apo, Orthorhombic P form)
To be published
8UR1
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BU of 8ur1 by Molmil
Crystal structure N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate bound halide free active site)
分子名称: CHLORIDE ION, GLYCEROL, N-acetylneuraminate lyase, ...
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-10-25
公開日2023-11-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate bound halide free active site)
To be published
4PFM
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SHEWANELLA BENTHICA DHDPS WITH LYSINE AND PYRUVATE
分子名称: 4-hydroxy-tetrahydrodipicolinate synthase, CITRATE ANION, GLYCEROL, ...
著者Wubben, J.M, Paxman, J.J, Dogovski, C, Panjikar, S, Perugini, M.A.
登録日2014-04-30
公開日2015-05-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.327 Å)
主引用文献Defining a Molecular Determinant of Lysine-Mediated Allosteric Inhibition of DHDPS.
To Be Published
2OJP
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BU of 2ojp by Molmil
The crystal structure of a dimeric mutant of Dihydrodipicolinate synthase from E.coli- DHDPS-L197Y
分子名称: Dihydrodipicolinate synthase, GLYCEROL
著者Griffin, M.D.W, Dobson, R.C.J, Antonio, L, Perugini, M.A, Jameson, G.B, Gerrard, J.A.
登録日2007-01-13
公開日2008-01-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Evolution of quaternary structure in a homotetrameric enzyme.
J.Mol.Biol., 380, 2008
2NUW
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2-keto-3-deoxygluconate aldolase from Sulfolobus acidocaldarius, native structure at 1.8 A resolution
分子名称: 2-keto-3-deoxygluconate/2-keto-3-deoxy-6-phospho gluconate aldolase, MAGNESIUM ION
著者van Eerde, A, Dijkstra, B.W.
登録日2006-11-10
公開日2007-04-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Biochemical and structural exploration of the catalytic capacity of Sulfolobus KDG aldolases
Biochem.J., 403, 2007
4ONV
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Crystal structure of YagE, a KDG aldolase protein in complex with 2-Keto-3-deoxy gluconate
分子名称: 1,2-ETHANEDIOL, 2-KETO-3-DEOXYGLUCONATE, GLYCEROL, ...
著者Manoj Kumar, P, Bhaskar, V, Manicka, S, Krishnaswamy, S.
登録日2014-01-29
公開日2015-01-14
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Crystal structure of YagE, a KDG aldolase protein in complex with 2-Keto-3-deoxy gluconate
To be Published
2NUX
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2-keto-3-deoxygluconate aldolase from Sulfolobus acidocaldarius, native structure in p6522 at 2.5 A resolution
分子名称: 2-keto-3-deoxygluconate/2-keto-3-deoxy-6-phospho gluconate aldolase, MAGNESIUM ION
著者van Eerde, A, Dijkstra, B.W.
登録日2006-11-10
公開日2007-04-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Biochemical and structural exploration of the catalytic capacity of Sulfolobus KDG aldolases
Biochem.J., 403, 2007
4R53
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dihydrodipicolinate synthase from C. jejuni with vacant active site and vacant allosteric site
分子名称: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, CHLORIDE ION, ...
著者Conly, C.J.T.
登録日2014-08-20
公開日2015-10-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Tyrosine 110 plays a critical role in regulating the allosteric inhibition of Campylobacter jejuni dihydrodipicolinate synthase by lysine.
Biochemistry, 53, 2014
2NUY
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2-keto-3-deoxygluconate aldolase from Sulfolobus acidocaldarius in complex with pyruvate
分子名称: 2-keto-3-deoxygluconate/2-keto-3-deoxy-6-phospho gluconate aldolase, MAGNESIUM ION, PYRUVIC ACID
著者van Eerde, A, Dijkstra, B.W.
登録日2006-11-10
公開日2007-04-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Biochemical and structural exploration of the catalytic capacity of Sulfolobus KDG aldolases
Biochem.J., 403, 2007
4AH7
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Structure of Wild Type Stapylococcus aureus N-acetylneuraminic acid lyase in complex with pyruvate
分子名称: N-ACETYLNEURAMINATE LYASE
著者Timms, N, Poyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Pearson, A.R, Berry, A.
登録日2012-02-03
公開日2013-01-23
最終更新日2013-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy.
Chembiochem, 14, 2013
4AMA
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Crystal Structure of N-acetylneuraminic acid lyase from Staphylococcus aureus with the chemical modification thia-lysine at position 165 in complex with pyruvate
分子名称: N-ACETYLNEURAMINATE LYASE
著者Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Pearson, A.R, Berry, A.
登録日2012-03-08
公開日2013-01-23
最終更新日2019-07-10
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural insights into the recovery of aldolase activity in N-acetylneuraminic acid lyase by replacement of the catalytically active lysine with gamma-thialysine by using a chemical mutagenesis strategy.
Chembiochem, 14, 2013

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