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PDB: 249 件

4K4T
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Poliovirus polymerase elongation complex (r4_form)
分子名称: GLYCEROL, RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*GP*GP*AP*AP*A)-3'), RNA (5'-R(*GP*GP*GP*AP*GP*AP*UP*GP*A)-3'), ...
著者Gong, P, Peersen, O.B.
登録日2013-04-12
公開日2013-05-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts.
Plos One, 8, 2013
4K4Z
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Coxsackievirus B3 polymerase elongation complex (r2_Mg_form)
分子名称: MAGNESIUM ION, RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*GP*UP*CP*GP*AP*AP*A)-3'), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*A)-3'), ...
著者Gong, P, Peersen, O.B.
登録日2013-04-12
公開日2013-05-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts.
Plos One, 8, 2013
4K4U
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BU of 4k4u by Molmil
Poliovirus polymerase elongation complex (r5_form)
分子名称: RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*UP*CP*GP*UP*CP*GP*AP*AP*A)-3'), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), RNA (5'-R(P*GP*GP*GP*GP*GP*AP*GP*AP*UP*GP*A)-3'), ...
著者Gong, P, Peersen, O.B.
登録日2013-04-12
公開日2013-05-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts.
Plos One, 8, 2013
5XE0
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Crystal structure of EV-D68-3Dpol in complex with GTP
分子名称: GUANOSINE-5'-TRIPHOSPHATE, Genome polyprotein
著者Xie, W, Wang, C, Wang, Z, Li, Q, Wang, C.
登録日2017-03-30
公開日2017-06-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure and Thermostability Characterization of Enterovirus D68 3Dpol
J. Virol., 91, 2017
4K4V
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Poliovirus polymerase elongation complex (r5+1_form)
分子名称: DNA/RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-D(P*C)-3'), RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*UP*CP*GP*UP*CP*GP*AP*AP*A)-3'), RNA-directed RNA polymerase 3D-POL, ...
著者Gong, P, Peersen, O.B.
登録日2013-04-12
公開日2013-05-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts.
Plos One, 8, 2013
4K4X
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BU of 4k4x by Molmil
Coxsackievirus B3 polymerase elongation complex (r2_form), rna
分子名称: GLYCEROL, MAGNESIUM ION, RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*GP*UP*CP*GP*AP*AP*A)-3'), ...
著者Gong, P, Peersen, O.B.
登録日2013-04-12
公開日2013-05-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts.
Plos One, 8, 2013
5Y6Z
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Crystal structure of the coxsackievirus A16 polymerase elongation complex
分子名称: GLYCEROL, Genome polyprotein, MAGNESIUM ION, ...
著者Bi, P, Shu, B, Gong, P.
登録日2017-08-15
公開日2017-12-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the coxsackievirus A16 RNA-dependent RNA polymerase elongation complex reveals novel features in motif A dynamics
Virol Sin, 32, 2017
1WAC
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BU of 1wac by Molmil
Back-priming mode of Phi6 RNA-dependent RNA polymerase
分子名称: P2 PROTEIN
著者Laurila, M.R.L, Salgado, P.S, Stuart, D.I, Grimes, J.M, Bamford, D.H.
登録日2004-10-26
公開日2005-01-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Back-Priming Mode of Phi6 RNA-Dependent RNA Polymerase
J.Gen.Virol., 86, 2005
3KNA
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M296I mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA
分子名称: 3D polymerase, MAGNESIUM ION, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), ...
著者Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R.
登録日2009-11-12
公開日2010-07-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin
J.Virol., 84, 2010
3KLV
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BU of 3klv by Molmil
M296I G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA
分子名称: 3D polymerase, MAGNESIUM ION, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), ...
著者Ferrer-Orta, C, Sierra, M, Agudo, R, Perez-Luque, R, Arias, A, Verdaguer, N.
登録日2009-11-09
公開日2010-07-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin
J.Virol., 84, 2010
5Y3D
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BU of 5y3d by Molmil
Structural insight into the interaction between RNA polymerase and VPg for norovirus replication
分子名称: RNA-dependent RNA polymerase, viral protein genome-linked (VPg)
著者Kim, K.H, Lee, J.-H, Seok, J.H.
登録日2017-07-28
公開日2018-07-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献Insight Into the Interaction Between RNA Polymerase and VPg for Murine Norovirus Replication.
Front Microbiol, 9, 2018
3KMQ
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BU of 3kmq by Molmil
G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA, tetragonal structure
分子名称: 3D polymerase, RNA (5'-R(*GP*GP*CP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*CP*C)-3')
著者Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R.
登録日2009-11-11
公開日2010-07-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin
J.Virol., 84, 2010
5ZIU
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BU of 5ziu by Molmil
Crystal structure of human Entervirus D68 RdRp
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, RdRp
著者Wang, M.L, Zhang, Y, Chen, Y.P, Lu, D.R, Jiang, H, Chen, Y.J, Li, L, Zhang, C.H, Shi, Q.L, Su, D.
登録日2018-03-17
公開日2019-04-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.147 Å)
主引用文献Crystal structure of human Entervirus D68 RdRp in complex with NADPH
To Be Published
1XR6
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BU of 1xr6 by Molmil
Crystal Structure of RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 1B
分子名称: Genome polyprotein, POTASSIUM ION
著者Love, R.A, Maegley, K.A, Yu, X, Ferre, R.A, Lingardo, L.K, Diehl, W, Parge, H.E, Dragovich, P.S, Fuhrman, S.A.
登録日2004-10-13
公開日2004-10-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy
Structure, 12, 2004
1XR7
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BU of 1xr7 by Molmil
Crystal structure of RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 16
分子名称: Genome polyprotein
著者Love, R.A, Maegley, K.A, Yu, X, Ferre, R.A, Lingardo, L.K, Diehl, W, Parge, H.E, Dragovich, P.S, Fuhrman, S.A.
登録日2004-10-13
公開日2004-10-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy
Structure, 12, 2004
1XR5
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BU of 1xr5 by Molmil
Crystal Structure of the RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 14
分子名称: Genome polyprotein, SAMARIUM (III) ION
著者Love, R.A, Maegley, K.A, Yu, X, Ferre, R.A, Lingardo, L.K, Diehl, W, Parge, H.E, Dragovich, P.S, Fuhrman, S.A.
登録日2004-10-13
公開日2004-10-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy
Structure, 12, 2004
5ZIT
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BU of 5zit by Molmil
Crystal structure of human Enterovirus D68 RdRp in complex with NADPH
分子名称: DI(HYDROXYETHYL)ETHER, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, RdRp
著者Wang, M.L, Li, L, Chen, Y.P, Jiang, H, Zhang, Y, Su, D.
登録日2018-03-17
公開日2019-04-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.196 Å)
主引用文献Structure of the enterovirus D68 RNA-dependent RNA polymerase in complex with NADPH implicates an inhibitor binding site in the RNA template tunnel.
J.Struct.Biol., 2020
3KMS
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BU of 3kms by Molmil
G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA trigonal structure
分子名称: 3D polymerase, MAGNESIUM ION, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), ...
著者Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R.
登録日2009-11-11
公開日2010-07-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin
J.Virol., 84, 2010
3KOA
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BU of 3koa by Molmil
M296I mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA and GTP
分子名称: 3D polymerase, DIPHOSPHATE, MAGNESIUM ION, ...
著者Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R.
登録日2009-11-13
公開日2010-07-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin
J.Virol., 84, 2010
1WNE
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BU of 1wne by Molmil
Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with a template-primer RNA
分子名称: 5'-R(*CP*AP*UP*GP*GP*GP*CP*C)-3', 5'-R(*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ...
著者Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N.
登録日2004-07-31
公開日2004-08-31
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of Foot-and-Mouth Disease Virus RNA-dependent RNA Polymerase and Its Complex with a Template-Primer RNA
J.Biol.Chem., 279, 2004
7W9S
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BU of 7w9s by Molmil
Crystal structure of the enterovirus 71 polymerase elongation complex (C1S3 form)
分子名称: CYTIDINE-5'-TRIPHOSPHATE, Genome polyprotein, MAGNESIUM ION, ...
著者Wang, M, Gong, P.
登録日2021-12-10
公開日2022-11-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Crystal structure of a pre-chemistry viral RNA-dependent RNA polymerase suggests participation of two basic residues in catalysis.
Nucleic Acids Res., 50, 2022
2D7S
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BU of 2d7s by Molmil
Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with VPg protein
分子名称: RNA-dependent RNA polymerase, VPg1 protein
著者Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N.
登録日2005-11-29
公開日2006-03-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of a protein primer-polymerase complex in the initiation of genome replication
Embo J., 25, 2006
2E9R
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BU of 2e9r by Molmil
Foot-and-mouth disease virus RNA-dependent RNA polymerase in complex with a template-primer RNA and with ribavirin
分子名称: 5'-R(*CP*AP*UP*GP*GP*GP*CP*CP*C)-3', 5'-R(*CP*CP*C*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ...
著者Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N.
登録日2007-01-26
公開日2007-06-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Sequential structures provide insights into the fidelity of RNA replication
Proc.Natl.Acad.Sci.Usa, 104, 2007
2EC0
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RNA-dependent RNA polymerase of foot-and-mouth disease virus in complex with a template-primer RNA and ATP
分子名称: 5'-R(*GP*GP*GP*CP*CP*CP*A)-3', 5'-R(P*AP*UP*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ...
著者Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N.
登録日2007-02-09
公開日2007-06-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Sequential structures provide insights into the fidelity of RNA replication
Proc.Natl.Acad.Sci.Usa, 104, 2007
2E9T
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Foot-and-mouth disease virus RNA-polymerase RNA dependent in complex with a template-primer RNA and 5F-UTP
分子名称: 5'-R(*GP*GP*GP*CP*CP*CP*(5FU))-3', 5'-R(P*UP*AP*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ...
著者Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N.
登録日2007-01-26
公開日2007-06-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Sequential structures provide insights into the fidelity of RNA replication
Proc.Natl.Acad.Sci.Usa, 104, 2007

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