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PDB: 394 件

7PH4
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AMP-PNP bound nanodisc reconstituted MsbA with nanobodies, spin-labeled at position T68C
分子名称: (1~{R},4~{R},11~{S},14~{S},19~{Z})-19-[2-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]ethylimino]-7,8,17,18-tetraoxa-1,4,11,14-tetrazatricyclo[12.6.2.2^{4,11}]tetracosane-6,9,16-trione, ATP-dependent lipid A-core flippase, DODECYL-BETA-D-MALTOSIDE, ...
著者Parey, K, Januliene, D, Galazzo, L, Meier, G, Vecchis, D, Striednig, B, Hilbi, H, Schaefer, L.V, Kuprov, I, Bordignon, E, Seeger, M.A, Moeller, A.
登録日2021-08-16
公開日2022-08-24
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献The ABC transporter MsbA adopts the wide inward-open conformation in E. coli cells.
Sci Adv, 8, 2022
8HF7
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Cryo-EM structure of ComA bound to its mature substrate CSP peptide
分子名称: Competence factor transporting ATP-binding protein/permease ComA, Competence-stimulating peptide type 1
著者Yu, L, Xin, X, Min, L.
登録日2022-11-09
公開日2023-10-11
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of peptide secretion for Quorum sensing by ComA.
Nat Commun, 14, 2023
7PQX
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Structure of CtAtm1 in the inward-facing open conformation
分子名称: Putative iron-sulfur protein
著者Li, P, Wang, K.T, Gourdon, P.E.
登録日2021-09-20
公開日2022-08-10
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria.
Nat Commun, 13, 2022
7PSD
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BU of 7psd by Molmil
Structure of CtAtm1(E603Q) in the inward-facing open conformation
分子名称: Putative iron-sulfur protein
著者Li, P, Wang, K.T, Gourdon, P.E.
登録日2021-09-22
公開日2022-08-10
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria.
Nat Commun, 13, 2022
7PRO
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BU of 7pro by Molmil
Structure of CtAtm1 in the inward-open with Glutathione-complexed [2Fe-2S] cluster bound
分子名称: Putative iron-sulfur protein
著者Li, P, Wang, K.T, Gourdon, P.E.
登録日2021-09-22
公開日2022-08-10
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria.
Nat Commun, 13, 2022
7PR1
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BU of 7pr1 by Molmil
Structure of CtAtm1 in the occluded conformation with ATP bound
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative iron-sulfur protein
著者Li, P, Wang, K.T, Gourdon, P.E.
登録日2021-09-20
公開日2022-08-10
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria.
Nat Commun, 13, 2022
7PRU
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Structure of CtAtm1 in the inward-facing partially occluded with cargo bound
分子名称: GLUTATHIONE, Putative iron-sulfur protein
著者Li, P, Wang, K.T, Gourdon, P.E.
登録日2021-09-22
公開日2022-08-10
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria.
Nat Commun, 13, 2022
7QKS
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Cryo-EM structure of ABC transporter STE6-2p from Pichia pastoris in apo conformation at 3.1 A resolution
分子名称: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, Plasma membrane ATP-binding cassette transporter required for the export of a-factor
著者Schleker, E.S.M, Reinhart, C.
登録日2021-12-18
公開日2022-10-26
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural and functional investigation of ABC transporter STE6-2p from Pichia pastoris reveals unexpected interaction with sterol molecules.
Proc.Natl.Acad.Sci.USA, 119, 2022
7QKR
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Cryo-EM structure of ABC transporter STE6-2p from Pichia pastoris with Verapamil at 3.2 A resolution
分子名称: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, Dexverapamil, MAGNESIUM ION, ...
著者Schleker, E.S.M, Reinhart, C.
登録日2021-12-18
公開日2022-10-26
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural and functional investigation of ABC transporter STE6-2p from Pichia pastoris reveals unexpected interaction with sterol molecules.
Proc.Natl.Acad.Sci.USA, 119, 2022
8HF5
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BU of 8hf5 by Molmil
Cryo-EM structure of nucleotide-bound ComA at outward-facing state with EC gate open conformation
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transport/processing ATP-binding protein ComA
著者Yu, L, Xin, X, Min, L.
登録日2022-11-09
公開日2023-10-04
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of peptide secretion for Quorum sensing by ComA.
Nat Commun, 14, 2023
8HF6
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Cryo-EM structure of nucleotide-bound ComA E647Q mutant
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Competence factor transporting ATP-binding protein/permease ComA
著者Yu, L, Xin, X, Min, L.
登録日2022-11-09
公開日2023-10-04
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of peptide secretion for Quorum sensing by ComA.
Nat Commun, 14, 2023
8HF4
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BU of 8hf4 by Molmil
Cryo-EM structure of nucleotide-bound ComA at outward-facing state with EC gate closed conformation
分子名称: PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transport/processing ATP-binding protein ComA
著者Yu, L, Xin, X, Min, L.
登録日2022-11-09
公開日2023-10-04
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of peptide secretion for Quorum sensing by ComA.
Nat Commun, 14, 2023
8I4B
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BU of 8i4b by Molmil
Cryo-EM structure of apo-form ABCC4
分子名称: ATP-binding cassette sub-family C member 4
著者Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q.
登録日2023-01-19
公開日2023-05-24
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Cryo-EM structure ofABCC4
Nat Cardiovasc Res, 2023
8I4A
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Cryo-EM structure of dipyridamole-bound ABCC4
分子名称: 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol, ATP-binding cassette sub-family C member 4
著者Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q.
登録日2023-01-19
公開日2023-05-24
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure ofABCC4
Nat Cardiovasc Res, 2023
8I4C
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Cryo-EM structure of U46619-bound ABCC4
分子名称: (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, ATP-binding cassette sub-family C member 4
著者Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q.
登録日2023-01-19
公開日2023-05-24
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Cryo-EM structure ofABCC4
Nat Cardiovasc Res, 2023
8HW4
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Cryo-EM structure of dehydroepiandrosterone sulfate-bound human ABC transporter ABCC3 in nanodiscs
分子名称: 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, ATP-binding cassette sub-family C member 3
著者Wang, J, Wang, F.F, Chen, Y.X, Zhou, C.Z.
登録日2022-12-28
公開日2023-06-07
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket.
Embo J., 42, 2023
8HVH
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BU of 8hvh by Molmil
Cryo-EM structure of ABC transporter ABCC3
分子名称: ATP-binding cassette sub-family C member 3
著者Wang, J, Wang, F.F, Chen, Y.X, Zhou, C.Z.
登録日2022-12-26
公開日2023-06-07
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket.
Embo J., 42, 2023
8HW2
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BU of 8hw2 by Molmil
Cryo-EM structure of beta-estradiol 17-(beta-D-glucuronide)-bound human ABC transporter ABCC3 in nanodiscs
分子名称: ATP-binding cassette sub-family C member 3, Estradiol-17beta-glucuronide
著者Wang, J, Wang, F.F, Chen, Y.X, Zhou, C.Z.
登録日2022-12-28
公開日2023-06-07
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket.
Embo J., 42, 2023
7SGR
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BU of 7sgr by Molmil
Structure of hemolysin A secretion system HlyB/D complex
分子名称: Alpha-hemolysin translocation ATP-binding protein HlyB, Membrane fusion protein (MFP) family protein,Hemolysin secretion protein D, chromosomal, ...
著者Zhao, H, Chen, J.
登録日2021-10-07
公開日2022-09-14
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献The hemolysin A secretion system is a multi-engine pump containing three ABC transporters.
Cell, 185, 2022
7SVR
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BU of 7svr by Molmil
The complex of dephosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) and Lumacaftor (VX-809)
分子名称: Cystic fibrosis transmembrane conductance regulator, Lumacaftor
著者Fiedorczuk, K, Chen, J.
登録日2021-11-19
公開日2022-01-12
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Mechanism of CFTR correction by type I folding correctors.
Cell, 185, 2022
7SV7
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BU of 7sv7 by Molmil
The complex of phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with ATP/Mg and Tezacaftor (VX-661)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, Cystic fibrosis transmembrane conductance regulator, ...
著者Fiedorczuk, K, Chen, J.
登録日2021-11-18
公開日2022-01-12
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Mechanism of CFTR correction by type I folding correctors.
Cell, 185, 2022
7SVD
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The complex of phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with ATP/Mg and Lumacaftor (VX-809)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, Cystic fibrosis transmembrane conductance regulator, ...
著者Fiedorczuk, K, Chen, J.
登録日2021-11-18
公開日2022-01-12
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Mechanism of CFTR correction by type I folding correctors.
Cell, 185, 2022
7T56
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Cryo-EM structure of PCAT1 in the inward-facing intermediate conformation under ATP turnover condition
分子名称: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kieuvongngam, V, Chen, J.
登録日2021-12-11
公開日2022-02-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T57
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Cryo-EM structure of PCAT1 in the inward-facing narrow conformation under ATP turnover condition
分子名称: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kieuvongngam, V, Chen, J.
登録日2021-12-11
公開日2022-02-02
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T54
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Cryo-EM structure of ATP-bound PCAT1 in the outward-facing conformation
分子名称: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE
著者Kieuvongngam, V, Chen, J.
登録日2021-12-11
公開日2022-02-02
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022

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