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PDB: 381 件

6RAN
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BU of 6ran by Molmil
Heterodimeric ABC exporter TmrAB in inward-facing wide conformation
分子名称: Multidrug resistance ABC transporter ATP-binding and permease protein, Nanobody Nb9F10
著者Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
登録日2019-04-06
公開日2019-07-31
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
6RAJ
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BU of 6raj by Molmil
Heterodimeric ABC exporter TmrAB in vanadate trapped outward-facing open conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, MAGNESIUM ION, ...
著者Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
登録日2019-04-06
公開日2019-07-31
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
6UJR
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BU of 6ujr by Molmil
P-glycoprotein mutant-F724A and C952A-with BDE100
分子名称: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
著者Aller, S.G, Le, C.A.
登録日2019-10-03
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
6UJT
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BU of 6ujt by Molmil
P-glycoprotein mutant-Y303A and C952A-with BDE100
分子名称: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
著者Aller, S.G, Le, C.A.
登録日2019-10-03
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.17 Å)
主引用文献Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
6UJW
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BU of 6ujw by Molmil
P-glycoprotein mutant-Y306A and C952A-with BDE100
分子名称: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
著者Aller, S.G, Le, C.A.
登録日2019-10-03
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.15 Å)
主引用文献Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
6UJP
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BU of 6ujp by Molmil
P-glycoprotein mutant-F979A and C952A-with BDE100
分子名称: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
著者Aller, S.G, Le, C.A.
登録日2019-10-03
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.98 Å)
主引用文献Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
6V9Z
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BU of 6v9z by Molmil
Cryo-EM structure of PCAT1 bound to its CtA peptide substrate
分子名称: ABC-type bacteriocin transporter, CtA
著者Kieuvongngam, V, Oldham, M.L, Chen, J.
登録日2019-12-16
公開日2020-01-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Structural basis of substrate recognition by a polypeptide processing and secretion transporter.
Elife, 9, 2020
7EKL
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BU of 7ekl by Molmil
Mitochondrial outer membrane protein
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family B member 6, MAGNESIUM ION
著者Zhang, S.S.
登録日2021-04-05
公開日2021-08-25
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Molecular insights into the human ABCB6 transporter.
Cell Discov, 7, 2021
6UZL
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BU of 6uzl by Molmil
Cryo-EM structure of nucleotide-free MsbA reconstituted into peptidiscs, conformation 2
分子名称: Lipid A export ATP-binding/permease protein MsbA
著者Angiulli, G, Walz, T, Dhupar, H.S, Suzuki, H, Wason, I.S, Duong Van Hoa, F.
登録日2019-11-15
公開日2020-03-04
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献New approach for membrane protein reconstitution into peptidiscs and basis for their adaptability to different proteins.
Elife, 9, 2020
6UY0
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BU of 6uy0 by Molmil
Cryo-EM structure of wild-type bovine multidrug resistance protein 1 (MRP1) under active turnover conditions
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ...
著者Johnson, Z.L, Chen, J.
登録日2019-11-09
公開日2020-06-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Characterization of the kinetic cycle of an ABC transporter by single-molecule and cryo-EM analyses.
Elife, 9, 2020
7E1A
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BU of 7e1a by Molmil
Human bile salt exporter ABCB11 in complex with taurocholate
分子名称: Bile salt export pump, TAUROCHOLIC ACID
著者Wang, L, How, W.T, Chen, Y.
登録日2021-02-01
公開日2022-02-09
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets.
Cell Res., 32, 2022
6UZ2
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BU of 6uz2 by Molmil
Cryo-EM structure of nucleotide-free MsbA reconstituted into peptidiscs, conformation 1
分子名称: Lipid A export ATP-binding/permease protein MsbA
著者Angiulli, G, Walz, T, Dhupar, H.S, Suzuki, H, Wason, I.S, Duong Van Hoa, F.
登録日2019-11-14
公開日2020-03-04
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献New approach for membrane protein reconstitution into peptidiscs and basis for their adaptability to different proteins.
Elife, 9, 2020
7D7N
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BU of 7d7n by Molmil
Cryo-EM structure of human ABCB6 transporter
分子名称: ATP-binding cassette sub-family B member 6, mitochondrial
著者Wang, C, Cao, C, Wang, N, Wang, X, Zhang, X.C.
登録日2020-10-05
公開日2020-10-21
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Cryo-electron microscopy structure of human ABCB6 transporter.
Protein Sci., 29, 2020
7EHL
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BU of 7ehl by Molmil
Cryo-EM structure of human ABCB8 transporter in nucleotide binding state
分子名称: CHOLESTEROL, MAGNESIUM ION, Mitochondrial potassium channel ATP-binding subunit, ...
著者Li, S.J, Yang, X, Shen, Y.Q.
登録日2021-03-29
公開日2021-05-05
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY
主引用文献Cryo-EM structure of human ABCB8 transporter in nucleotide binding state.
Biochem.Biophys.Res.Commun., 557, 2021
6RAH
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BU of 6rah by Molmil
Heterodimeric ABC exporter TmrAB in ATP-bound outward-facing open conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance ABC transporter ATP-binding and permease protein, ...
著者Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
登録日2019-04-06
公開日2019-07-31
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
6RAM
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BU of 6ram by Molmil
Heterodimeric ABC exporter TmrAB under turnover conditions in asymmetric unlocked return conformation with wider opened intracellular gate
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
登録日2019-04-06
公開日2019-07-31
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
6UJN
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BU of 6ujn by Molmil
P-glycoprotein mutant-C952A-with BDE100
分子名称: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
著者Aller, S.G, Le, C.A.
登録日2019-10-03
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.98 Å)
主引用文献Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
6RAK
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BU of 6rak by Molmil
Heterodimeric ABC exporter TmrAB in vanadate trapped outward-facing occluded conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, MAGNESIUM ION, ...
著者Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
登録日2019-04-06
公開日2019-07-31
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
6VQU
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BU of 6vqu by Molmil
Structure of a bacterial Atm1-family ABC exporter
分子名称: ATM1-type heavy metal exporter
著者Fan, C, Rees, D.C.
登録日2020-02-05
公開日2020-07-29
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.88 Å)
主引用文献A structural framework for unidirectional transport by a bacterial ABC exporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
6RAI
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BU of 6rai by Molmil
Heterodimeric ABC exporter TmrAB in ATP-bound outward-facing occluded conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance ABC transporter ATP-binding and permease protein, ...
著者Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
登録日2019-04-06
公開日2019-07-31
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
7DQV
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BU of 7dqv by Molmil
Crystal structure of a CmABCB1 mutant
分子名称: DECYL-BETA-D-MALTOPYRANOSIDE, MAGNESIUM ION, NITRATE ION, ...
著者Matsuoka, K, Nakatsu, T, Kato, H.
登録日2020-12-24
公開日2021-03-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The crystal structure of the CmABCB1 G132V mutant, which favors the outward-facing state, reveals the mechanism of the pivotal joint between TM1 and TM3.
Protein Sci., 30, 2021
6UJS
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BU of 6ujs by Molmil
P-glycoprotein mutant-F728A and C952A-with BDE100
分子名称: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
著者Aller, S.G, Le, C.A.
登録日2019-10-03
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.17 Å)
主引用文献Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
6RAL
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BU of 6ral by Molmil
Heterodimeric ABC exporter TmrAB under turnover conditions in asymmetric unlocked return conformation
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
登録日2019-04-06
公開日2019-07-31
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
6RAF
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BU of 6raf by Molmil
Heterodimeric ABC exporter TmrAB in inward-facing narrow conformation under turnover conditions
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Anti-vesicular stomatitis virus N VHH, ...
著者Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
登録日2019-04-06
公開日2019-07-31
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
7DV5
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BU of 7dv5 by Molmil
Human bile salt exporter ABCB11 in complex with taurocholate
分子名称: Bile salt export pump, TAUROCHOLIC ACID
著者Wang, L, How, W.T, Chen, Y.
登録日2021-01-12
公開日2022-01-19
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets.
Cell Res., 32, 2022

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件を2024-07-10に公開中

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