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PDB: 381 件
8I4C
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Cryo-EM structure of U46619-bound ABCC4
分子名称: (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, ATP-binding cassette sub-family C member 4
著者Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q.
登録日2023-01-19
公開日2023-05-24
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Cryo-EM structure ofABCC4
Nat Cardiovasc Res, 2023
8IPT
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Cryo-EM structure of heme transporter CydDC from Escherichia coli in the occluded ATP bound state
分子名称: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC, ...
著者Zhu, C, Li, J.
登録日2023-03-14
公開日2023-06-14
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures of a prokaryotic heme transporter CydDC.
Protein Cell, 14, 2023
8IPS
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Cryo-EM structure of heme transporter CydDC from Escherichia coli in the inward facing heme loading state
分子名称: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC, ...
著者Zhu, C, Li, J.
登録日2023-03-14
公開日2023-06-14
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures of a prokaryotic heme transporter CydDC.
Protein Cell, 14, 2023
8IPR
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Cryo-EM structure of heme transporter CydDC from Mycobacterium smegmatis in the outward facing ATP bound state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Component linked with the assembly of cytochrome' ABC transporter ATP-binding protein CydC, MAGNESIUM ION, ...
著者Zhu, C, Li, J.
登録日2023-03-14
公開日2023-06-14
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM structures of a prokaryotic heme transporter CydDC.
Protein Cell, 14, 2023
8IPQ
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Cryo-EM structure of heme transporter CydDC from Mycobacterium smegmatis in the inward facing apo state
分子名称: Component linked with the assembly of cytochrome' ABC transporter ATP-binding protein CydC, Transmembrane ATP-binding protein ABC transporter cydD
著者Zhu, C, Li, J.
登録日2023-03-14
公開日2023-06-14
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures of a prokaryotic heme transporter CydDC.
Protein Cell, 14, 2023
8IZ8
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BU of 8iz8 by Molmil
cryo EM structure of apo hMRP4
分子名称: ATP-binding cassette sub-family C member 4
著者Liu, Z.M, Huang, Y.
登録日2023-04-06
公開日2024-04-10
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献cryo EM structure of apo hMRP4
To Be Published
8IZ7
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BU of 8iz7 by Molmil
cryo-EM structure of sulindac-bound hMRP4
分子名称: ATP-binding cassette sub-family C member 4, [(1Z)-5-fluoro-2-methyl-1-{4-[methylsulfinyl]benzylidene}-1H-inden-3-yl]acetic acid
著者Liu, Z.M, Huang, Y.
登録日2023-04-06
公開日2024-04-10
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献cryo-EM structure of sulindac-bound hMRP4
To Be Published
8IZP
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Multidrug resistance-associated protein 3
分子名称: ATP-binding cassette sub-family C member 3
著者Yun, C.H, Gao, H.M.
登録日2023-04-07
公開日2024-04-10
実験手法ELECTRON MICROSCOPY (3.31 Å)
主引用文献structure of multidrug resistance-associated protein 3 at 3.31 Angstroms
To Be Published
8IZR
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Multidrug resistance-associated protein 3
分子名称: ATP-binding cassette sub-family C member 2
著者Yun, C.H, Gao, H.M.
登録日2023-04-07
公開日2024-04-10
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献structure of multidrug resistance-associated protein 2 at 3.62 Angstroms resolution
To Be Published
8J3Z
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BU of 8j3z by Molmil
Cryo-EM structure of ATP-U46619-bound ABCC4
分子名称: (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 4, ...
著者Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q.
登録日2023-04-18
公開日2023-05-24
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Cryo-EM structure ofABCC4
Nat Cardiovasc Res, 2023
8J3W
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Cryo-EM structure of aspirin-bound ABCC4
分子名称: 2-(ACETYLOXY)BENZOIC ACID, ATP-binding cassette sub-family C member 4
著者Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q.
登録日2023-04-18
公開日2023-05-24
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Cryo-EM structure ofABCC4
Nat Cardiovasc Res, 2023
8IZ9
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BU of 8iz9 by Molmil
cryo-EM structure of PGE1-bound hMRP4
分子名称: 7-[(1R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid, ATP-binding cassette sub-family C member 4
著者Liu, Z.M, Huang, Y.
登録日2023-04-06
公開日2024-04-10
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献cryo-EM structure of PGE1-bound hMRP4
To Be Published
8IZA
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BU of 8iza by Molmil
cryo-EM structure of ATP-bound hMRP4
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 4, MAGNESIUM ION
著者Liu, Z.M, Huang, Y.
登録日2023-04-06
公開日2024-04-10
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献cryo-EM structure of ATP-bound hMRP4
To Be Published
7S5X
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BU of 7s5x by Molmil
Human KATP channel in open conformation, focused on Kir and one SUR, position 1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
著者Zhao, C, MacKinnon, R.
登録日2021-09-12
公開日2021-12-01
最終更新日2021-12-08
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
7S5V
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BU of 7s5v by Molmil
Human KATP channel in open conformation, focused on SUR
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
著者Zhao, C, MacKinnon, R.
登録日2021-09-12
公開日2021-12-01
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
7S5Y
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BU of 7s5y by Molmil
Human KATP channel in open conformation, focused on Kir and one SUR, position 2
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
著者Zhao, C, MacKinnon, R.
登録日2021-09-12
公開日2021-12-01
最終更新日2021-12-08
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
7SGR
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BU of 7sgr by Molmil
Structure of hemolysin A secretion system HlyB/D complex
分子名称: Alpha-hemolysin translocation ATP-binding protein HlyB, Membrane fusion protein (MFP) family protein,Hemolysin secretion protein D, chromosomal, ...
著者Zhao, H, Chen, J.
登録日2021-10-07
公開日2022-09-14
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献The hemolysin A secretion system is a multi-engine pump containing three ABC transporters.
Cell, 185, 2022
7SVR
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BU of 7svr by Molmil
The complex of dephosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) and Lumacaftor (VX-809)
分子名称: Cystic fibrosis transmembrane conductance regulator, Lumacaftor
著者Fiedorczuk, K, Chen, J.
登録日2021-11-19
公開日2022-01-12
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Mechanism of CFTR correction by type I folding correctors.
Cell, 185, 2022
7SV7
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BU of 7sv7 by Molmil
The complex of phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with ATP/Mg and Tezacaftor (VX-661)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, Cystic fibrosis transmembrane conductance regulator, ...
著者Fiedorczuk, K, Chen, J.
登録日2021-11-18
公開日2022-01-12
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Mechanism of CFTR correction by type I folding correctors.
Cell, 185, 2022
7SVD
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BU of 7svd by Molmil
The complex of phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with ATP/Mg and Lumacaftor (VX-809)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, Cystic fibrosis transmembrane conductance regulator, ...
著者Fiedorczuk, K, Chen, J.
登録日2021-11-18
公開日2022-01-12
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Mechanism of CFTR correction by type I folding correctors.
Cell, 185, 2022
7T56
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Cryo-EM structure of PCAT1 in the inward-facing intermediate conformation under ATP turnover condition
分子名称: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kieuvongngam, V, Chen, J.
登録日2021-12-11
公開日2022-02-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T54
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Cryo-EM structure of ATP-bound PCAT1 in the outward-facing conformation
分子名称: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE
著者Kieuvongngam, V, Chen, J.
登録日2021-12-11
公開日2022-02-02
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T57
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Cryo-EM structure of PCAT1 in the inward-facing narrow conformation under ATP turnover condition
分子名称: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kieuvongngam, V, Chen, J.
登録日2021-12-11
公開日2022-02-02
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T55
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Cryo-EM structure of PCAT1 in the inward-facing wide conformation under ATP turnover condition
分子名称: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kieuvongngam, V, Chen, J.
登録日2021-12-11
公開日2022-02-02
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
7SEL
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E. coli MsbA in complex with LPS and inhibitor G7090 (compound 3)
分子名称: (2E)-3-{7-[(1S)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-1-methylnaphthalen-2-yl}prop-2-enoic acid, (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]-5-oxidanyl-oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, ATP-dependent lipid A-core flippase
著者Payandeh, J, Koth, C.M, Verma, V.A.
登録日2021-09-30
公開日2022-03-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.978 Å)
主引用文献Discovery of Inhibitors of the Lipopolysaccharide Transporter MsbA: From a Screening Hit to Potent Wild-Type Gram-Negative Activity.
J.Med.Chem., 65, 2022

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件を2024-07-10に公開中

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