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PDB: 659 件
4Q2Q
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ZO1 PDZ3 in Complex with a Phage-Derived Peptide
分子名称: Tight junction protein ZO-1
著者Appleton, B.A, Wiesmann, C.
登録日2014-04-09
公開日2014-09-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献A structural portrait of the PDZ domain family.
J.Mol.Biol., 426, 2014
4Q2O
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BU of 4q2o by Molmil
PDLIM4 PDZ in Complex with a Phage-Derived Peptide
分子名称: PDZ and LIM domain protein 4
著者Appleton, B.A, Wiesmann, C.
登録日2014-04-09
公開日2014-09-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A structural portrait of the PDZ domain family.
J.Mol.Biol., 426, 2014
4NNM
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Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to Y-iCAL36 (YPTSII) peptide
分子名称: GLYCEROL, TIP-1 PDZ domain, Tax1-binding protein 3
著者Amacher, J.F, Madden, D.R.
登録日2013-11-18
公開日2015-01-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A CAL Inhibitor with Single-PDZ Specificity Rescues deltaF508-CFTR
To be Published
4Q6H
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CFTR Associated Ligand (CAL) bound to last 6 residues of CFTR (decameric peptide: iCAL36VQDTRL)
分子名称: CFTR-associated ligand, SULFITE ION, iCAL36-VQDTRL peptide
著者Amacher, J.F, Madden, D.R.
登録日2014-04-22
公開日2014-05-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献Understanding PDZ Affinity and Selectivity: All Residues Considered
TO BE PUBLISHED
4Q6S
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CFTR Associated Ligand (CAL) PDZ bound to biotinylated peptide BT-L-iCAL36
分子名称: BT-L-iCAL36 peptide, Golgi-associated PDZ and coiled-coil motif-containing protein
著者Amacher, J.F, Madden, D.R.
登録日2014-04-23
公開日2015-04-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Modulator Preferences are Critical Co-Determinants of PDZ Network Wiring
To be Published
4Q2P
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NHERF3 PDZ2 in Complex with a Phage-Derived Peptide
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Na(+)/H(+) exchange regulatory cofactor NHE-RF3
著者Appleton, B.A, Wiesmann, C.
登録日2014-04-09
公開日2014-09-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A structural portrait of the PDZ domain family.
J.Mol.Biol., 426, 2014
4Q3H
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The crystal structure of NHERF1 PDZ2 CXCR2 complex revealed by the NHERF1 CXCR2 chimeric protein
分子名称: Na(+)/H(+) exchange regulatory cofactor NHE-RF1
著者Holcomb, J, Jiang, Y, Trescott, L, Lu, G, Brunzelle, J, Sirinupong, N, Li, C, Yang, Z.
登録日2014-04-11
公開日2014-05-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.443 Å)
主引用文献Crystal structure of the NHERF1 PDZ2 domain in complex with the chemokine receptor CXCR2 reveals probable modes of PDZ2 dimerization.
Biochem.Biophys.Res.Commun., 448, 2014
4Q2N
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INADL PDZ3 in Complex with a Phage-Derived Peptide
分子名称: 1,2-ETHANEDIOL, InaD-like protein
著者Appleton, B.A, Wiesmann, C.
登録日2014-04-09
公開日2014-09-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A structural portrait of the PDZ domain family.
J.Mol.Biol., 426, 2014
4PQW
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Crystal Structure of Phospholipase C beta 3 in Complex with PDZ1 of NHERF1
分子名称: CHLORIDE ION, NICKEL (II) ION, Na(+)/H(+) exchange regulatory cofactor NHE-RF1
著者Jiang, Y, Wang, S, Holcomb, J, Trescott, L, Guan, X, Hou, Y, Brunzelle, J, Sirinupong, N, Li, C, Yang, Z.
登録日2014-03-04
公開日2014-04-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Crystallographic analysis of NHERF1-PLC beta 3 interaction provides structural basis for CXCR2 signaling in pancreatic cancer.
Biochem.Biophys.Res.Commun., 446, 2014
2PDZ
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BU of 2pdz by Molmil
SOLUTION STRUCTURE OF THE SYNTROPHIN PDZ DOMAIN IN COMPLEX WITH THE PEPTIDE GVKESLV, NMR, 15 STRUCTURES
分子名称: PEPTIDE GVKESLV, SYNTROPHIN
著者Schultz, J, Hoffmueller, U, Ashurst, J, Krause, G, Schmieder, P, Macias, M, Schneider-Mergener, J, Oschkinat, H.
登録日1997-12-10
公開日1998-12-30
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Specific interactions between the syntrophin PDZ domain and voltage-gated sodium channels.
Nat.Struct.Biol., 5, 1998
2PA1
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BU of 2pa1 by Molmil
Structure of the PDZ domain of human PDLIM2 bound to a C-terminal extension from human beta-tropomyosin
分子名称: CHLORIDE ION, PDZ and LIM domain protein 2
著者Uppenberg, J, Shrestha, L, Elkins, J, Burgess-Brown, N, Salah, E, Bunkoczi, G, Papagrigoriou, E, Pike, A.C.W, Turnbull, A.P, Ugochukwu, E, Umeano, C, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
登録日2007-03-27
公開日2007-05-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms
Protein Sci., 19, 2010
2OPG
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BU of 2opg by Molmil
The crystal structure of the 10th PDZ domain of MPDZ
分子名称: Multiple PDZ domain protein, SODIUM ION
著者Gileadi, C, Phillips, C, Elkins, J, Papagrigoriou, E, Ugochukwu, E, Gorrec, F, Savitsky, P, Umeano, C, Berridge, G, Gileadi, O, Salah, E, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
登録日2007-01-29
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of the 10th PDZ domain of MPDZ
To be Published
2OSG
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Solution Structure and Binding Property of the Domain-swapped Dimer of ZO2PDZ2
分子名称: Tight junction protein ZO-2
著者Wu, J.W, Yang, Y.S, Zhang, J.H, Ji, P, Wu, J.H, Shi, Y.Y.
登録日2007-02-05
公開日2007-09-25
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Domain-swapped Dimerization of the Second PDZ Domain of ZO2 May Provide a Structural Basis for the Polymerization of Claudins
J.Biol.Chem., 282, 2007
2PKT
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BU of 2pkt by Molmil
Crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1
分子名称: ACETATE ION, CALCIUM ION, CHLORIDE ION, ...
著者Uppenberg, J, Gileadi, C, Elkins, J, Bray, J, Burgess-Brown, N, Salah, E, Gileadi, O, Bunkoczi, G, Ugochukwu, E, Umeano, C, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
登録日2007-04-18
公開日2007-05-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms
Protein Sci., 19, 2010
2QKT
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BU of 2qkt by Molmil
Crystal Structure of the 5th PDZ domain of InaD
分子名称: Inactivation-no-after-potential D protein
著者Ranganathan, R, Socolich, M.
登録日2007-07-11
公開日2007-11-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Dynamic Scaffolding in a G Protein-Coupled Signaling System.
Cell(Cambridge,Mass.), 131, 2007
2QKU
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BU of 2qku by Molmil
The 5th PDZ Domain of InaD in 10mM DTT
分子名称: GLYCEROL, Inactivation-no-after-potential D protein
著者Ranganathan, R, Socolich, M, Wall, M.
登録日2007-07-11
公開日2007-11-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dynamic Scaffolding in a G Protein-Coupled Signaling System.
Cell(Cambridge,Mass.), 131, 2007
2REY
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BU of 2rey by Molmil
Crystal structure of the PDZ domain of human dishevelled 2 (homologous to Drosophila dsh)
分子名称: Segment polarity protein dishevelled homolog DVL-2
著者Papagrigoriou, E, Gileadi, C, Elkins, J, Cooper, C, Ugochukwu, E, Turnbull, A, Pike, A.C.W, Gileadi, O, von Delft, F, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Doyle, D, Structural Genomics Consortium (SGC)
登録日2007-09-27
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structure of the PDZ domains of human dishevelled 2 (homologous to Drosophila dsh).
To be Published
2QBW
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BU of 2qbw by Molmil
The crystal structure of PDZ-Fibronectin fusion protein
分子名称: PDZ-Fibronectin fusion protein, Polypeptide
著者Huang, J, Makabe, K, Koide, A, Koide, S.
登録日2007-06-18
公開日2008-04-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Design of protein function leaps by directed domain interface evolution.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2Q9V
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Crystal structure of the C890S mutant of the 4th PDZ domain of human membrane associated guanylate kinase
分子名称: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
著者Pilka, E.S, Hozjan, V, Kavanagh, K.L, Papagrigoriou, E, Cooper, C, Elkins, J.M, Doyle, D.A, von Delft, F, Sundstrom, M, Arrowsmith, C.A, Weigelt, J, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2007-06-14
公開日2007-06-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the C890S mutant of the 4th PDZ domain of human membrane associated guanylate kinase.
To be Published
2QG1
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Crystal structure of the 11th PDZ domain of MPDZ (MUPP1)
分子名称: 1,2-ETHANEDIOL, Multiple PDZ domain protein
著者Papagrigoriou, E, Salah, E, Phillips, C, Savitsky, P, Boisguerin, P, Oschkinat, H, Gileadi, C, Yang, X, Elkins, J.M, Ugochukwu, E, Bunkoczi, G, Uppenberg, J, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Doyle, D, Structural Genomics Consortium (SGC)
登録日2007-06-28
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of the 11th PDZ domain of MPDZ (MUPP1).
To be Published
2PKU
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Solution structure of PICK1 PDZ in complex with the carboxyl tail peptide of GluR2
分子名称: PRKCA-binding protein, peptide (GLU)(SER)(VAL)(LYS)(ILE)
著者Pan, L, Wu, H, Shen, C, Shi, Y, Xia, J, Zhang, M.
登録日2007-04-18
公開日2007-11-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes
Embo J., 26, 2007
2OQS
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Structure of the hDLG/SAP97 PDZ2 in complex with HPV-18 papillomavirus E6 peptide
分子名称: C-terminal HPV-18 E6 peptide, Disks large homolog 1
著者Liu, Y, Baleja, J.D, Henry, G.D, Hegde, R.S.
登録日2007-02-01
公開日2007-09-04
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the hDlg/SAP97 PDZ2 domain and its mechanism of interaction with HPV-18 papillomavirus E6 protein.
Biochemistry, 46, 2007
2RRM
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Interplay between phosphatidyl-inositol-phosphates and claudins upon binding to the 1st PDZ domain of zonula occludens 1
分子名称: Tight junction protein ZO-1
著者Hiroaki, H, Satomura, K, Goda, N, Umetsu, Y, Taniguchi, R, Ikegami, T, Furuse, M.
登録日2011-01-06
公開日2011-05-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献1H, 13C, and 15N resonance assignment of the first PDZ domain of mouse ZO-1
Biomol.Nmr Assign., 5, 2011
2PNT
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Crystal structure of the PDZ domain of human GRASP (GRP1) in complex with the C-terminal peptide of the metabotropic glutamate receptor type 1
分子名称: CHLORIDE ION, General receptor for phosphoinositides 1-associated scaffold protein
著者Elkins, J, Papagrigoriou, E, Cooper, C, Gileadi, C, Uppenberg, J, Bray, J, von Delft, F, Pike, A.C.W, Ugochukwu, E, Umeano, C, Gileadi, O, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
登録日2007-04-25
公開日2007-05-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.148 Å)
主引用文献Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms
Protein Sci., 19, 2010
2R4H
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Crystal structure of a C1190S mutant of the 6th PDZ domain of human membrane associated guanylate kinase
分子名称: HISTIDINE, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
著者Ugochukwu, E, Pilka, E.S, Hozjan, V, Kavanagh, K.L, Cooper, C, Pike, A.C.W, Elkins, J.M, Doyle, D.A, von Delft, F, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2007-08-31
公開日2007-10-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of a C1190S mutant of the 6th PDZ domain of human membrane associated guanylate kinase.
To be Published

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件を2024-06-26に公開中

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