4Q3H
The crystal structure of NHERF1 PDZ2 CXCR2 complex revealed by the NHERF1 CXCR2 chimeric protein
Summary for 4Q3H
Entry DOI | 10.2210/pdb4q3h/pdb |
Descriptor | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (2 entities in total) |
Functional Keywords | scaffold protein, dimerization, neutrophil chemotaxis, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P25025 |
Total number of polymer chains | 2 |
Total formula weight | 19832.47 |
Authors | Holcomb, J.,Jiang, Y.,Trescott, L.,Lu, G.,Brunzelle, J.,Sirinupong, N.,Li, C.,Yang, Z. (deposition date: 2014-04-11, release date: 2014-05-21, Last modification date: 2024-02-28) |
Primary citation | Holcomb, J.,Jiang, Y.,Guan, X.,Trescott, L.,Lu, G.,Hou, Y.,Wang, S.,Brunzelle, J.,Sirinupong, N.,Li, C.,Yang, Z. Crystal structure of the NHERF1 PDZ2 domain in complex with the chemokine receptor CXCR2 reveals probable modes of PDZ2 dimerization. Biochem.Biophys.Res.Commun., 448:169-174, 2014 Cited by PubMed: 24768637DOI: 10.1016/j.bbrc.2014.04.085 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.443 Å) |
Structure validation
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