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PDB: 292 件
2YNR
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mImp_alphadIBB_B54NLS
分子名称: B54NLS, IMPORTIN SUBUNIT ALPHA
著者Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B.
登録日2012-10-18
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals.
Plant Cell, 24, 2012
5Z8H
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APC with an inhibitor
分子名称: Adenomatous polyposis coli protein, GLYCEROL, Peptide inhibitor
著者Zhang, J, Yang, X.Y, Song, K.
登録日2018-01-31
公開日2019-02-06
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献APC with an inhibitor
To Be Published
5EKF
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Crystallization and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a XPG NLS Peptide, fragment 1
分子名称: DNA repair protein complementing XP-G cells, Importin subunit alpha-1
著者Barros, A.C, Takeda, A.A.S, Fontes, M.R.M.
登録日2015-11-03
公開日2016-02-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence.
J.Mol.Biol., 428, 2016
2YNS
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rImp_alpha_B54NLS
分子名称: B54NLS, IMPORTIN SUBUNIT ALPHA-1A
著者Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B.
登録日2012-10-18
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals.
Plant Cell, 24, 2012
6WBB
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BU of 6wbb by Molmil
Structure of Mouse Importin alpha - MLH1-E475A NLS peptide complex
分子名称: DNA mismatch repair protein Mlh1, Importin subunit alpha-1
著者De Barros, A.C, Da Silva, T.D, Oliveira, H.C, Fukuda, C.A, Fontes, M.R.M.
登録日2020-03-26
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.663 Å)
主引用文献Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
6WBA
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Structure of Mouse Importin alpha MLH1- R470A NLS Peptide Complex
分子名称: DNA mismatch repair protein Mlh1, Importin subunit alpha-1
著者de Barros, A.C, da Silva, T.D, Oliveira, H.C, Fukuda, C.A, Fontes, M.R.M.
登録日2020-03-26
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.151 Å)
主引用文献Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
6WBC
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Structure of Mouse Importin alpha- MLH1-R472K NLS Peptide Complex
分子名称: DNA mismatch repair protein Mlh1, Importin subunit alpha-1
著者de Barros, A.C, da Silva, T.D, Oliveira, H.C, Fukuda, C.A, Fontes, M.R.M.
登録日2020-03-26
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
5EKG
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Crystallization and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a XPG NLS Peptide, fragment 2
分子名称: Importin subunit alpha-1, XPG2 peptide
著者Barros, A.C, Takeda, A.A.S, Fontes, M.R.M.
登録日2015-11-03
公開日2016-02-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence.
J.Mol.Biol., 428, 2016
3AU3
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Crystal structure of armadillo repeat domain of APC
分子名称: Adenomatous polyposis coli protein
著者Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2011-01-28
公開日2011-11-02
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of the armadillo repeat domain of adenomatous polyposis coli and its complex with the tyrosine-rich domain of sam68
Structure, 19, 2011
4OIH
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Importin Alpha in Complex with the Bipartite NLS of Prp20
分子名称: Guanine nucleotide exchange factor SRM1, Importin subunit alpha-1
著者Roman, N, Christie, M, Swarbrick, C.M.D, Kobe, B, Forwood, J.K.
登録日2014-01-19
公開日2014-02-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Characterisation of the Nuclear Import Receptor Importin Alpha in Complex with the Bipartite NLS of Prp20
Plos One, 8, 2013
1BK5
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KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE
分子名称: COBALT (II) ION, KARYOPHERIN ALPHA
著者Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J.
登録日1998-07-14
公開日1999-01-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
1BK6
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KARYOPHERIN ALPHA (YEAST) + SV40 T ANTIGEN NLS
分子名称: KARYOPHERIN ALPHA, LARGE T ANTIGEN
著者Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J.
登録日1998-07-14
公開日1999-01-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
1EE4
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CRYSTAL STRUCTURE OF YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A C-MYC NLS PEPTIDE
分子名称: KARYOPHERIN ALPHA, MYC PROTO-ONCOGENE PROTEIN
著者Conti, E.
登録日2000-01-30
公開日2000-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha.
Structure Fold.Des., 8, 2000
4RXH
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Crystal Structure of Importin-alpha from Neurospora crassa complexed with SV40NLS
分子名称: Importin subunit alpha, Large T antigen
著者Bernardes, N.E, Takeda, A.A.S, Fontes, M.R.M.
登録日2014-12-11
公開日2015-07-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7553 Å)
主引用文献Structure of Importin-alpha from a Filamentous Fungus in Complex with a Classical Nuclear Localization Signal.
Plos One, 10, 2015
1EJY
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MOUSE IMPORTIN ALPHA-NUCLEOPLASMIN NLS PEPTIDE COMPLEX
分子名称: IMPORTIN ALPHA, NUCLEOPLASMIN NLS PEPTIDE
著者Fontes, M.R, Teh, T, Kobe, B.
登録日2000-03-05
公開日2000-04-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha.
J.Mol.Biol., 297, 2000
1EJL
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BU of 1ejl by Molmil
MOUSE IMPORTIN ALPHA-SV40 LARGE T ANTIGEN NLS PEPTIDE COMPLEX
分子名称: IMPORTIN ALPHA, SV40 LARGE T ANTIGEN NLS PEPTIDE
著者Fontes, M.R, Teh, T, Kobe, B.
登録日2000-03-03
公開日2000-04-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha.
J.Mol.Biol., 297, 2000
1EE5
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YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A NUCLEOPLASMIN NLS PEPTIDE
分子名称: KARYOPHERIN ALPHA, NUCLEOPLASMIN
著者Conti, E.
登録日2000-01-30
公開日2000-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha.
Structure Fold.Des., 8, 2000
4XZR
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BU of 4xzr by Molmil
Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh1
分子名称: Importin subunit alpha, Inner nuclear membrane protein SRC1
著者Lokareddy, R.K, Cingolani, G.
登録日2015-02-04
公開日2015-06-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2.
Structure, 23, 2015
8Y0P
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Beta-Catenin in complex with peptide 301
分子名称: B-cell CLL/lymphoma 9 protein, Catenin beta-1, PROLINE
著者Tim, F.
登録日2024-01-22
公開日2024-04-17
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Beta-Catenin in complex with peptide 301
To Be Published
4YI0
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Structure of mouse importin a1 bound to Pom121NLS
分子名称: Importin subunit alpha-1, Nuclear envelope pore membrane protein POM 121
著者Lokareddy, R.K, Cingolani, G.
登録日2015-02-27
公開日2016-01-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.806 Å)
主引用文献Mammalian Pom121 and yeast Heh2 share IBB-like NLSs that support targeting to the inner nuclear membrane
To Be Published
6IUA
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BU of 6iua by Molmil
Crystal structure of importin-alpha1 bound to the 53BP1 nuclear localization signal (S1678D)
分子名称: Importin subunit alpha-1, Peptide from TP53-binding protein 1
著者Matsuura, Y.
登録日2018-11-27
公開日2019-01-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and biochemical characterization of the recognition of the 53BP1 nuclear localization signal by importin-alpha.
Biochem. Biophys. Res. Commun., 510, 2019
6IW8
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Crystal structure of Importin-alpha and wild-type GM130
分子名称: Importin subunit alpha-1, Peptide from Golgin subfamily A member 2
著者Chang, C.-C, Chen, C.-J, Pien, Y.-C, Tsai, S.-Y, Hsia, K.-C.
登録日2018-12-04
公開日2019-10-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-alpha.
Nat Commun, 10, 2019
4YK6
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Crystal structure of APC-ARM in complexed with Amer1-A4
分子名称: APC membrane recruitment protein 1, Adenomatous polyposis coli protein
著者Zhang, Z, Xiao, Y, Wu, G.
登録日2015-03-04
公開日2016-03-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners
Cell Discov, 1, 2015
4ZDU
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Crystal structure of importin-alpha bound to a non-classical nuclear localization signal of the influenza A virus nucleoprotein
分子名称: Importin subunit alpha-1, Peptide from Nucleoprotein
著者Nakada, R, Hirano, H, Matsuura, Y.
登録日2015-04-19
公開日2015-10-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of importin-alpha bound to a non-classical nuclear localization signal of the influenza A virus nucleoprotein
Sci Rep, 5, 2015
4YJE
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Crystal structure of APC-ARM in complexed with Amer1-A1
分子名称: APC membrane recruitment protein 1, Adenomatous polyposis coli protein
著者Zhang, Z, Xiao, Y, Wu, G.
登録日2015-03-03
公開日2016-03-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners
Cell Discov, 1, 2015

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