4K2O
 
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4K2P
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3TCA
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4NSW
 | | Crystal structure of the BAR-PH domain of ACAP1 | | 分子名称: | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 | | 著者 | Pang, X, Zhang, K, Ma, J, Zhou, Q, Sun, F. | | 登録日 | 2013-11-29 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A PH Domain in ACAP1 Possesses Key Features of the BAR Domain in Promoting Membrane Curvature
Dev.Cell, 31, 2014
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8SZ4
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8SXZ
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8SZ7
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8T0R
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8T0K
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8SZ8
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8TYM
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8TYN
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2LUL
 | | Solution NMR Structure of PH Domain of Tyrosine-protein kinase Tec from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR3504C | | 分子名称: | Tyrosine-protein kinase Tec, ZINC ION | | 著者 | Liu, G, Xiao, R, Janjua, H, Hamilton, K, Shastry, R, Kohan, E, Acton, T.B, Everett, J.K, Lee, H, Pederson, K, Huang, Y.J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2012-06-15 | | 公開日 | 2012-08-15 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR Structure of PH Domain of Tyrosine-protein kinase Tec from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR3504C
To be Published
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3ZYS
 | | Human dynamin 1 deltaPRD polymer stabilized with GMPPCP | | 分子名称: | DYNAMIN-1, INTERFERON-INDUCED GTP-BINDING PROTEIN MX1 | | 著者 | Chappie, J.S, Mears, J.A, Fang, S, Leonard, M, Schmid, S.L, Milligan, R.A, Hinshaw, J.E, Dyda, F. | | 登録日 | 2011-08-24 | | 公開日 | 2011-10-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (12.2 Å) | | 主引用文献 | A Pseudoatomic Model of the Dynamin Polymer Identifies a Hydrolysis-Dependent Powerstroke.
Cell(Cambridge,Mass.), 147, 2011
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3ZVR
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2Q13
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2R09
 | | Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchange Factor | | 分子名称: | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Cytohesin-3, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, ... | | 著者 | DiNitto, J.P, Delprato, A, Gabe Lee, M.T, Cronin, T.C, Huang, S, Guilherme, A, Czech, M.P, Lambright, D.G. | | 登録日 | 2007-08-17 | | 公開日 | 2007-12-04 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange Factors.
Mol.Cell, 28, 2007
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2Z0O
 | | Crystal structure of APPL1-BAR-PH domain | | 分子名称: | DCC-interacting protein 13-alpha | | 著者 | Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-05-07 | | 公開日 | 2008-05-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Crystal structure of APPL1-BAR-PH domain
To be Published
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2Z0P
 | | Crystal structure of PH domain of Bruton's tyrosine kinase | | 分子名称: | (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, Tyrosine-protein kinase BTK, ZINC ION | | 著者 | Murayama, K, Kato-Murayama, M, Mishima, C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-05-07 | | 公開日 | 2008-05-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Crystal structure of the Bruton's tyrosine kinase PH domain with phosphatidylinositol
Biochem.Biophys.Res.Commun., 377, 2008
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2YS3
 | | Solution structure of the PH domain of Kindlin-3 from human | | 分子名称: | Unc-112-related protein 2 | | 著者 | Li, H, Sato, M, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-04-03 | | 公開日 | 2007-10-09 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the PH domain of Kindlin-3 from human
To be Published
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3A8Q
 | | Low-resolution crystal structure of the Tiam2 PHCCEx domain | | 分子名称: | T-lymphoma invasion and metastasis-inducing protein 2 | | 著者 | Terawaki, S, Kitano, K, Mori, T, Zhai, Y, Higuchi, Y, Itoh, N, Watanabe, T, Kaibuchi, K, Hakoshima, T. | | 登録日 | 2009-10-07 | | 公開日 | 2009-11-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module
Embo J., 29, 2010
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3A8P
 | | Crystal structure of the Tiam2 PHCCEx domain | | 分子名称: | T-lymphoma invasion and metastasis-inducing protein 2 | | 著者 | Terawaki, S, Kitano, K, Mori, T, Zhai, Y, Higuchi, Y, Itoh, N, Watanabe, T, Kaibuchi, K, Hakoshima, T. | | 登録日 | 2009-10-07 | | 公開日 | 2009-11-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module
Embo J., 29, 2010
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3A8N
 | | Crystal structure of the Tiam1 PHCCEx domain | | 分子名称: | T-lymphoma invasion and metastasis-inducing protein 1 | | 著者 | Terawaki, S, Kitano, K, Mori, T, Zhai, Y, Higuchi, Y, Itoh, N, Watanabe, T, Kaibuchi, K, Hakoshima, T. | | 登録日 | 2009-10-07 | | 公開日 | 2009-11-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module
Embo J., 29, 2010
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2ELB
 | | Crystal Structure of the BAR-PH domain of human APPL1 | | 分子名称: | Adapter protein containing PH domain, PTB domain and leucine zipper motif 1 | | 著者 | Li, J, Mao, X, Dong, L.Q, Liu, F, Tong, L. | | 登録日 | 2007-03-27 | | 公開日 | 2007-05-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structures of the BAR-PH and PTB Domains of Human APPL1
Structure, 15, 2007
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5KCV
 | | Crystal structure of allosteric inhibitor, ARQ 092, in complex with autoinhibited form of AKT1 | | 分子名称: | 3-[3-[4-(1-azanylcyclobutyl)phenyl]-5-phenyl-imidazo[4,5-b]pyridin-2-yl]pyridin-2-amine, RAC-alpha serine/threonine-protein kinase | | 著者 | Eathiraj, S. | | 登録日 | 2016-06-07 | | 公開日 | 2016-06-29 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Discovery of 3-(3-(4-(1-Aminocyclobutyl)phenyl)-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine (ARQ 092): An Orally Bioavailable, Selective, and Potent Allosteric AKT Inhibitor.
J.Med.Chem., 59, 2016
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