6FJC
 
 | | Human KIBRA C2 domain mutant C771A in complex with phosphatidylinositol 3,4,5-trisphosphate | | 分子名称: | (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, GLYCEROL, Protein KIBRA, ... | | 著者 | Crennell, S.J, Posner, M.G, Bagby, S. | | 登録日 | 2018-01-22 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.598 Å) | | 主引用文献 | Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain.
J. Biol. Chem., 293, 2018
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4NS0
 | | The C2A domain of Rabphilin 3A in complex with PI(4,5)P2 | | 分子名称: | Rabphilin-3A, SULFATE ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | | 著者 | Guillen, J, Ferrer-Orta, C, Buxaderas, M, Perez-sanchez, D, Guerrero-Valero, M, Luengo-Gil, G, Pous, J, Guerra, P, Gomez-Fernandez, J.C, Verdaguer, N, Corbalan-Garcia, S. | | 登録日 | 2013-11-27 | | 公開日 | 2013-12-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4NPK
 | | Extended-Synaptotagmin 2, C2A- and C2B-domains, calcium bound | | 分子名称: | CALCIUM ION, Extended synaptotagmin-2 | | 著者 | Tomchick, D.R, Rizo, J, Xu, J. | | 登録日 | 2013-11-21 | | 公開日 | 2014-01-29 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.552 Å) | | 主引用文献 | Structure and ca(2+)-binding properties of the tandem c2 domains of e-syt2.
Structure, 22, 2014
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1BCI
 | | C2 DOMAIN OF CYTOSOLIC PHOSPHOLIPASE A2, NMR, MINIMIZED AVERAGE STRUCTURE | | 分子名称: | CALCIUM ION, CYTOSOLIC PHOSPHOLIPASE A2 | | 著者 | Xu, G.Y, Mcdonagh, T, Yu, H.A, Nalefski, E.A, Clark, J.D, Cumming, D.A. | | 登録日 | 1998-04-30 | | 公開日 | 1998-11-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and membrane interactions of the C2 domain of cytosolic phospholipase A2.
J.Mol.Biol., 280, 1998
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1BYN
 | | SOLUTION STRUCTURE OF THE CALCIUM-BOUND FIRST C2-DOMAIN OF SYNAPTOTAGMIN I | | 分子名称: | CALCIUM ION, PROTEIN (SYNAPTOTAGMIN I) | | 著者 | Shao, X, Fernandez, I, Sudhof, T.C, Rizo, J. | | 登録日 | 1998-10-18 | | 公開日 | 1998-10-21 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: does Ca2+ induce a conformational change?
Biochemistry, 37, 1998
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1A25
 | | C2 DOMAIN FROM PROTEIN KINASE C (BETA) | | 分子名称: | CALCIUM ION, O-PHOSPHOETHANOLAMINE, PROTEIN KINASE C (BETA) | | 著者 | Sutton, R.B, Sprang, S.R. | | 登録日 | 1998-01-16 | | 公開日 | 1998-05-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+.
Structure, 6, 1998
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1DSY
 | | C2 DOMAIN FROM PROTEIN KINASE C (ALPHA) COMPLEXED WITH CA2+ AND PHOSPHATIDYLSERINE | | 分子名称: | 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, CALCIUM ION, PHOSPHATE ION, ... | | 著者 | Verdaguer, N, Corbalan-Garcia, S, Ochoa, W.F, Fita, I, Gomez-Fernandez, J.C. | | 登録日 | 2000-01-10 | | 公開日 | 2000-01-26 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine.
EMBO J., 18, 1999
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1DQV
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1TJM
 | | Crystallographic Identification of Sr2+ Coordination Site in Synaptotagmin I C2B Domain | | 分子名称: | GLYCEROL, STRONTIUM ION, Synaptotagmin I | | 著者 | Cheng, Y, Sequeira, S.M, Malinina, L, Tereshko, V, Sollner, T.H, Patel, D.J. | | 登録日 | 2004-06-06 | | 公開日 | 2004-09-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | | 主引用文献 | Crystallographic identification of Ca2+ and Sr2+ coordination sites in synaptotagmin I C2B domain
Protein Sci., 13, 2004
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5UG7
 | | Calcium bound Perforin C2 Domain - T431D | | 分子名称: | CALCIUM ION, Perforin-1 | | 著者 | Law, R.H.P, Conroy, P.J, Voskoboinik, I, Whisstock, J.C. | | 登録日 | 2017-01-07 | | 公開日 | 2018-02-07 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin.
Cell Death Differ., 25, 2018
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1UGK
 | | Solution structure of the first C2 domain of synaptotagmin IV from human fetal brain (KIAA1342) | | 分子名称: | Synaptotagmin IV | | 著者 | Nagashima, T, Hayashi, F, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Matsuo, Y, Ohara, O, Nagase, T, Kikuno, R, Nakayama, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-06-16 | | 公開日 | 2003-12-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the first C2 domain of synaptotagmin IV from human fetal brain (KIAA1342)
To be Published
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1V27
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1RSY
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5VFF
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1TJX
 | | Crystallographic Identification of Ca2+ Coordination Sites in Synaptotagmin I C2B Domain | | 分子名称: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | | 著者 | Cheng, Y, Sequeira, S.M, Malinina, L, Tereshko, V, Sollner, T.H, Patel, D.J. | | 登録日 | 2004-06-07 | | 公開日 | 2004-11-23 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | | 主引用文献 | Crystallographic identification of Ca2+ and Sr2+ coordination sites in synaptotagmin I C2B domain.
Protein Sci., 13, 2004
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5VFG
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5UG6
 | | Perforin C2 Domain - T431D | | 分子名称: | IODIDE ION, Perforin-1 | | 著者 | Law, R.H.P, Conroy, P.J, Voskoboinik, I, Whisstock, J.C. | | 登録日 | 2017-01-07 | | 公開日 | 2018-02-07 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin.
Cell Death Differ., 25, 2018
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5VFE
 | | Synaptotagmin 1 C2A domain, lead-bound | | 分子名称: | LEAD (II) ION, SULFATE ION, Synaptotagmin-1 | | 著者 | Taylor, A.B, Hart, P.J, Igumenova, T.I. | | 登録日 | 2017-04-07 | | 公開日 | 2018-04-11 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | High affinity interactions of Pb2+with synaptotagmin I.
Metallomics, 10, 2018
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1UOW
 | | Calcium binding domain C2B | | 分子名称: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | | 著者 | Cheng, Y, Sequeira, S.M, Sollner, T.H, Patel, D.J. | | 登録日 | 2003-09-24 | | 公開日 | 2004-09-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | | 主引用文献 | Crystallographic Identification of Ca2+ and Sr2+ Coordination Sites in Synaptotagmin I C2B Domain
Protein Sci., 13, 2004
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1UOV
 | | Calcium binding domain C2B | | 分子名称: | CALCIUM ION, GLYCEROL, SYNAPTOTAGMIN I | | 著者 | Cheng, Y, Sequeira, S.M, Sollner, T.H, Patel, D.J. | | 登録日 | 2003-09-24 | | 公開日 | 2004-09-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystallographic Identification of Ca2+ and Sr2+ Coordination Sites in Synaptotagmin I C2B Domain
Protein Sci., 13, 2004
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5T0R
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5T0S
 | | Synaptotagmin 1 C2B domain, cadmium-bound | | 分子名称: | CADMIUM ION, SODIUM ION, Synaptotagmin-1 | | 著者 | Taylor, A.B, Hart, P.J, Igumenova, T.I. | | 登録日 | 2016-08-16 | | 公開日 | 2017-06-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Non-Native Metal Ion Reveals the Role of Electrostatics in Synaptotagmin 1-Membrane Interactions.
Biochemistry, 56, 2017
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5W4S
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1W15
 | | rat synaptotagmin 4 C2B domain in the presence of calcium | | 分子名称: | CALCIUM ION, CHLORIDE ION, SODIUM ION, ... | | 著者 | Dai, H, Shin, O.-H, Machius, M, Tomchick, D.R, Sudhof, T.C, Rizo, J. | | 登録日 | 2004-06-16 | | 公開日 | 2004-08-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Structural Basis for the Evolutionary Inactivation of Ca2+ Binding to Synaptotagmin 4
Nat.Struct.Mol.Biol., 11, 2004
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1W16
 | | rat synaptotagmin 4 C2B domain in the absence of calcium | | 分子名称: | CHLORIDE ION, SODIUM ION, SYNAPTOTAGMIN IV | | 著者 | Dai, H, Shin, O.-H, Machius, M, Tomchick, D.R, Sudhof, T.C, Rizo, J. | | 登録日 | 2004-06-16 | | 公開日 | 2004-08-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Basis for the Evolutionary Inactivation of Ca2+ Binding to Synaptotagmin 4
Nat.Struct.Mol.Biol., 11, 2004
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