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PDB: 111 件
3BVH
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Crystal Structure of Recombinant gammaD364A Fibrinogen Fragment D with the Peptide Ligand Gly-Pro-Arg-Pro-Amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 4-mer peptide GPRP, CALCIUM ION, ...
著者Bowley, S.R, Merenbloom, B.K, Betts, L, Okumura, N, Heroux, A, Gorkun, O.V, Lord, S.T.
登録日2008-01-07
公開日2008-09-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Polymerization-defective fibrinogen variant gammaD364A binds knob "A" peptide mimic.
Biochemistry, 47, 2008
2XNY
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A fragment of streptococcal M1 protein in complex with human fibrinogen
分子名称: FIBRINOGEN ALPHA CHAIN, FIBRINOGEN BETA CHAIN, FIBRINOGEN GAMMA CHAIN, ...
著者Macheboeuf, P, Y Fu, C, Zinkernagel, A.S, Johnson, J.E, Nizet, V, Ghosh, P.
登録日2010-08-06
公開日2011-04-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (7.5 Å)
主引用文献Streptococcal M1 Protein Constructs a Pathological Host Fibrinogen Network
Nature, 472, 2011
1N8E
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Fragment Double-D from Human Fibrin
分子名称: Fibrin alpha/alpha-E chain, Fibrin beta chain, Fibrin gamma chain
著者Yang, Z, Pandi, L, Doolittle, R.F.
登録日2002-11-20
公開日2003-01-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献The Crystal Structure of Fragment Double-D from Cross-Linked Lamprey Fibrin Reveals Isopeptide Linkages across an Unexpected D-D Interface
Biochemistry, 41, 2002
1N86
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Crystal structure of human D-dimer from cross-linked fibrin complexed with GPR and GHRPLDK peptide ligands.
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, CALCIUM ION, Fibrin alpha/alpha-E chain, ...
著者Yang, Z, Pandi, L, Doolittle, R.F.
登録日2002-11-19
公開日2003-01-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface.
Biochemistry, 41, 2002
1N73
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Fibrin D-Dimer, Lamprey complexed with the PEPTIDE LIGAND: GLY-HIS-ARG-PRO-AMIDE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrin alpha-1 chain, ...
著者Yang, Z, Pandi, L, Doolittle, R.F.
登録日2002-11-12
公開日2003-01-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface
Biochemistry, 41, 2002
2OYI
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Crystal Structure of Fragment D of gammaD298,301A Fibrinogen with the Peptide Ligand Gly-Pro-Arg-Pro-Amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha chain, ...
著者Kostelansky, M.S, Gorkun, O.V, Lord, S.T.
登録日2007-02-22
公開日2007-05-15
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Probing the gamma2 Calcium-Binding Site: Studies with gammaD298,301A Fibrinogen Reveal Changes in the gamma294-301 Loop that Alter the Integrity of the "a" Polymerization Site.
Biochemistry, 46, 2007
2OYH
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Crystal Structure of Fragment D of gammaD298,301A Fibrinogen with the Peptide Ligand Gly-His-Arg-Pro-Amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha chain, ...
著者Kostelansky, M.S, Gorkun, O.V, Lord, S.T.
登録日2007-02-22
公開日2007-05-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Probing the gamma2 Calcium-Binding Site: Studies with gammaD298,301A Fibrinogen Reveal Changes in the gamma294-301 Loop that Alter the Integrity of the "a" Polymerization Site.
Biochemistry, 46, 2007
2Q9I
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Crystal Structure of D-Dimer from Human Fibrin Complexed with Met-His-Arg-Pro-Tyr-amide.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrin B Knob (GHRPam), ...
著者Doolittle, R.F, Pandi, L.
登録日2007-06-12
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini
Biochemistry, 46, 2007
2FFD
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Fibrinogen Fragment D with "A" knob peptide mimic GPRVVE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E Chain, ...
著者Betts, L.
登録日2005-12-19
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献The structure of fibrinogen fragment D with the 'A' knob peptide GPRVVE.
THROMB.HAEMOST., 4, 2006
1RE4
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Crystal Structure of Fragment D of BbetaD398A Fibrinogen
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
著者Kostelansky, M.S, Betts, L, Gorkun, O.V, Lord, S.T.
登録日2003-11-06
公開日2004-05-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献BbetaGlu397 and BbetaAsp398 but not BbetaAsp432 are required for "B:b" interactions.
Biochemistry, 43, 2004
1RE3
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Crystal Structure of Fragment D of BbetaD398A Fibrinogen with the Peptide Ligand Gly-His-Arg-Pro-Amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
著者Kostelansky, M.S, Betts, L, Gorkun, O.V, Lord, S.T.
登録日2003-11-06
公開日2004-05-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献BbetaGlu397 and BbetaAsp398 but not BbetaAsp432 are required for "B:b" interactions.
Biochemistry, 43, 2004
1RF0
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Crystal Structure of Fragment D of gammaE132A Fibrinogen
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
著者Kostelansky, M.S, Gorkun, O.V, Lord, S.T.
登録日2003-11-07
公開日2004-03-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Calcium-Binding Site beta2, Adjacent to the "b" Polymerization Site, Modulates Lateral Aggregation of Protofibrils during Fibrin Polymerization.
Biochemistry, 43, 2004
3E1I
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Crystal Structure of BbetaD432A Variant Fibrinogen Fragment D with the Peptide Ligand Gly-His-Arg-Pro-amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha chain, ...
著者Bowley, S.R, Lord, S.T.
登録日2008-08-04
公開日2009-01-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Fibrinogen variant BbetaD432A has normal polymerization but does not bind knob "B".
Blood, 113, 2009
1RF1
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Crystal Structure of Fragment D of gammaE132A Fibrinogen with the Peptide Ligand Gly-His-Arg-Pro-amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
著者Kostelansky, M.S, Gorkun, O.V, Lord, S.T.
登録日2003-11-07
公開日2004-03-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Calcium-Binding Site beta2, Adjacent to the "b" Polymerization Site, Modulates Lateral Aggregation of Protofibrils during Fibrin Polymerization.
Biochemistry, 43, 2004
3GHG
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BU of 3ghg by Molmil
Crystal Structure of Human Fibrinogen
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A knob, B knob, ...
著者Doolittle, R.F, Kollman, J.M, Sawaya, M.R, Pandi, L, Riley, M.
登録日2009-03-03
公開日2009-05-19
最終更新日2023-05-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of human fibrinogen.
Biochemistry, 48, 2009
3H32
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Crystal structure of D-dimer from human fibrin complexed with Gly-His-Arg-Pro-Tyr-amide
分子名称: CALCIUM ION, Fibrin B knob pentapeptide, Fibrinogen alpha chain, ...
著者Doolittle, R.F, Pandi, L.
登録日2009-04-15
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Two families of synthetic peptides that enhance fibrin turbidity and delay fibrinolysis by different mechanisms.
Biochemistry, 48, 2009
4K0V
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Structural basis for angiopoietin-1 mediated signaling initiation
分子名称: Angiopoietin-1, TEK tyrosine kinase variant
著者Yu, X, Seegar, T.C.M, Dalton, A.C, Tzvetkova-Robev, D, Goldgur, Y, Nikolov, D.B, Barton, W.A.
登録日2013-04-04
公開日2013-05-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4.51 Å)
主引用文献Structural basis for angiopoietin-1-mediated signaling initiation.
Proc.Natl.Acad.Sci.USA, 110, 2013
1LTJ
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Crystal Structure of Recombinant Human Fibrinogen Fragment D with the Peptide Ligands Gly-Pro-Arg-Pro-Amide and Gly-His-Arg-Pro-Amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen Beta chain, ...
著者Kostelansky, M.S, Betts, L, Gorkun, O.V, Lord, S.T.
登録日2002-05-20
公開日2002-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献2.8 A Crystal Structures of Recombinant Fibrinogen Fragment D with and without Two Peptide Ligands: GHRP Binding to the "b" Site Disrupts Its Nearby Calcium-binding Site.
Biochemistry, 41, 2002
1LWU
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Crystal structure of fragment D from lamprey fibrinogen complexed with the peptide Gly-His-Arg-Pro-amide
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yang, Z, Spraggon, G, Pandi, L, Everse, S.J, Riley, M, Doolittle, R.F.
登録日2002-06-03
公開日2002-08-23
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of fragment D from lamprey fibrinogen complexed with the peptide Gly-His-Arg-Pro-amide.
Biochemistry, 41, 2002
1LT9
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Crystal Structure of Recombinant Human Fibrinogen Fragment D
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
著者Kostelansky, M.S, Betts, L, Gorkun, O.V, Lord, S.T.
登録日2002-05-20
公開日2002-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献2.8 A Crystal Structures of Recombinant Fibrinogen Fragment D with and without Two Peptide Ligands: GHRP Binding to the "b" Site Disrupts Its Nearby Calcium-binding Site.
Biochemistry, 41, 2002
1M1J
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Crystal structure of native chicken fibrinogen with two different bound ligands
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Yang, Z, Kollman, J.M, Pandi, L, Doolittle, R.F.
登録日2002-06-19
公開日2002-06-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of Native Chicken Fibrinogen at 2.7 A Resolution
Biochemistry, 40, 2001
1DEQ
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THE CRYSTAL STRUCTURE OF MODIFIED BOVINE FIBRINOGEN (AT ~4 ANGSTROM RESOLUTION)
分子名称: FIBRINOGEN, FIBRINOGEN (ALPHA CHAIN), FIBRINOGEN (BETA CHAIN), ...
著者Brown, J.H, Volkmann, N, Jun, G, Henschen-Edman, A.H, Cohen, C.
登録日1999-11-15
公開日2000-02-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The crystal structure of modified bovine fibrinogen.
Proc.Natl.Acad.Sci.USA, 97, 2000
1EI3
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CRYSTAL STRUCTURE OF NATIVE CHICKEN FIBRINOGEN
分子名称: FIBRINOGEN
著者Yang, Z, Mochalkin, I, Veerapandian, L, Riley, M, Doolittle, R.F.
登録日2000-02-23
公開日2000-05-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (5.5 Å)
主引用文献Crystal structure of native chicken fibrinogen at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 97, 2000
1FZA
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CRYSTAL STRUCTURE OF FIBRINOGEN FRAGMENT D
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN
著者Spraggon, G, Everse, S.J, Doolittle, R.F.
登録日1997-08-05
公開日1997-12-03
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structures of fragment D from human fibrinogen and its crosslinked counterpart from fibrin.
Nature, 389, 1997
1FZF
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CRYSTAL STRUCTURE OF FRAGMENT DOUBLE-D FROM HUMAN FIBRIN WITH THE PEPTIDE LIGAND GLY-HIS-ARG-PRO-AMIDE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN
著者Everse, S.J, Spraggon, G, Veerapandian, L, Doolittle, R.F.
登録日1998-12-28
公開日1999-06-08
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
Biochemistry, 38, 1999

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