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PDB: 273 件
5N2H
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BU of 5n2h by Molmil
Structure of the E9 DNA polymerase exonuclease deficient mutant (D166A+E168A) from vaccinia virus
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Tarbouriech, N, Burmeister, W.P, Iseni, F.
登録日2017-02-07
公開日2017-11-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding.
Nat Commun, 8, 2017
5VU7
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BU of 5vu7 by Molmil
TNA polymerase, open ternary complex
分子名称: 5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXYTETRAHYDROFURAN-3-YL DIHYDROGEN PHOSPHATE, DNA polymerase, DNA template, ...
著者Chim, N, Chaput, J.C.
登録日2017-05-18
公開日2017-12-06
最終更新日2017-12-13
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structural basis for TNA synthesis by an engineered TNA polymerase.
Nat Commun, 8, 2017
3CFO
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BU of 3cfo by Molmil
Triple Mutant APO structure
分子名称: DNA polymerase, GUANOSINE, SULFATE ION
著者Wang, J, Klimenko, D, Wang, M, Steitz, T.A, Konigsberg, W.H.
登録日2008-03-04
公開日2009-03-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Insights into base selectivity from the structures of an RB69 DNA Polymerase triple mutant
To be Published
3CFP
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BU of 3cfp by Molmil
Structure of the replicating complex of a POL Alpha family DNA Polymerase, ternary complex 1
分子名称: CALCIUM ION, CHLORIDE ION, DNA (5'-D(*DAP*DCP*DAP*DGP*DGP*DTP*DAP*DAP*DGP*DCP*DAP*DGP*DTP*DCP*DCP*DGP*DCP*DG)-3'), ...
著者Wang, J, Klimenko, D, Wang, M, Steitz, T.A, Konigsberg, W.H.
登録日2008-03-04
公開日2009-03-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Insights into base selectivity from the structures of an RB69 DNA Polymerase triple mutant
To be Published
5N2G
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BU of 5n2g by Molmil
Structure of the E9 DNA polymerase from vaccinia virus in complex with manganese
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Tarbouriech, N, Burmeister, W.P, Iseni, F.
登録日2017-02-07
公開日2017-11-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding.
Nat Commun, 8, 2017
3CQ8
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BU of 3cq8 by Molmil
Ternary complex of the L415F mutant RB69 exo(-)polymerase
分子名称: CALCIUM ION, DNA (5'-D(*DAP*DCP*DAP*DGP*DGP*DTP*DAP*DAP*DGP*DCP*DAP*DGP*DTP*DCP*DCP*DGP*DCP*DG)-3'), DNA (5'-D(*DGP*DCP*DGP*DGP*DAP*DCP*DTP*DGP*DCP*DTP*DTP*DAP*DCP*DC)-3'), ...
著者Zhong, X, Pedersen, L.C, Kunkel, T.A.
登録日2008-04-02
公開日2008-09-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Characterization of a replicative DNA polymerase mutant with reduced fidelity and increased translesion synthesis capacity.
Nucleic Acids Res., 36, 2008
2OZS
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BU of 2ozs by Molmil
Crystal structure of RB69 gp43 in complex with DNA with dATP opposite dTMP
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA polymerase, MAGNESIUM ION, ...
著者Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S.
登録日2007-02-27
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide.
Biochemistry, 46, 2007
2OZM
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BU of 2ozm by Molmil
Crystal structure of RB69 gp43 in complex with DNA with 5-NITP opposite an abasic site analog
分子名称: 1-{2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-NITRO -1H-INDOLE, DNA polymerase, MAGNESIUM ION, ...
著者Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S.
登録日2007-02-26
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Caught Bending the A-Rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide
Biochemistry, 46, 2007
1Q9Y
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BU of 1q9y by Molmil
CRYSTAL STRUCTURE OF ENTEROBACTERIA PHAGE RB69 GP43 DNA POLYMERASE COMPLEXED WITH 8-OXOGUANOSINE CONTAINING DNA
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-AC(8-OXOGUANOSINE)GGTAAGCAGTCCGCG-3', 5'-GCGGACTGCTTAC(DIDEOXYCYTIDINE)-3', ...
著者Freisinger, E, Grollman, A.P, Miller, H, Kisker, C.
登録日2003-08-26
公開日2004-04-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Lesion (in)tolerance reveals insights into DNA replication fidelity.
Embo J., 23, 2004
1QQC
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BU of 1qqc by Molmil
CRYSTAL STRUCTURE OF AN ARCHAEBACTERIAL DNA POLYMERASE D.TOK
分子名称: DNA POLYMERASE II, MAGNESIUM ION, SULFATE ION
著者Zhao, Y, Jeruzalmi, D, Leighton, L, Lasken, R, Kuriyan, J.
登録日1999-06-02
公開日1999-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of an archaebacterial DNA polymerase
Structure Fold.Des., 7, 1999
1QHT
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BU of 1qht by Molmil
DNA POLYMERASE FROM THERMOCOCCUS SP. 9ON-7 ARCHAEON
分子名称: PROTEIN (DNA POLYMERASE)
著者Park, H.-W, Rodriguez, A.C, Beese, L.S.
登録日1999-05-26
公開日2000-05-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of a pol alpha family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9 degrees N-7.
J.Mol.Biol., 299, 2000
8UCU
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BU of 8ucu by Molmil
Partial DNA termination subcomplex of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ...
著者Mullins, E.A, Chazin, W.J, Eichman, B.F.
登録日2023-09-27
公開日2023-10-11
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8UCW
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BU of 8ucw by Molmil
Complete DNA termination subcomplex 2 of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ...
著者Mullins, E.A, Chazin, W.C, Eichman, B.F.
登録日2023-09-27
公開日2023-10-11
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8UCV
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BU of 8ucv by Molmil
Complete DNA termination subcomplex 1 of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ...
著者Mullins, E.A, Chazin, W.C, Eichman, B.F.
登録日2023-09-27
公開日2023-10-11
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
1Q8I
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BU of 1q8i by Molmil
Crystal structure of ESCHERICHIA coli DNA Polymerase II
分子名称: DNA polymerase II
著者Brunzelle, J.S, Muchmore, C.R.A, Mashhoon, N, Blair-Johnson, M, Shuvalova, L, Goodman, M.F, Anderson, W.F, Midwest Center for Structural Genomics (MCSG)
登録日2003-08-21
公開日2004-01-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Escherichia Coli DNA Polymerase II
To be Published
7B0H
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BU of 7b0h by Molmil
TgoT_6G12 Ternary complex
分子名称: DNA (5'-D(P*AP*AP*CP*GP*GP*CP*AP*AP*AP*TP*GP*CP*G)-3'), DNA (5'-D(P*CP*GP*CP*AP*TP*T)-3'), DNA polymerase, ...
著者Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M.
登録日2020-11-19
公開日2021-01-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution.
Biomolecules, 10, 2020
7B08
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BU of 7b08 by Molmil
TgoT apo
分子名称: DNA polymerase, THYMIDINE-5'-TRIPHOSPHATE, TRIETHYLENE GLYCOL
著者Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M.
登録日2020-11-18
公開日2020-12-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.394 Å)
主引用文献Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution.
Biomolecules, 10, 2020
8Q3R
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BU of 8q3r by Molmil
Cryo-EM structure of the DNA polymerase holoenzyme E9-A20-D4 of vaccinia virus
分子名称: DNA polymerase, DNA polymerase processivity factor component OPG148, Uracil-DNA glycosylase
著者Burmeister, W.P, Ballandras-Colas, A, Boettcher, B, Grimm, C.
登録日2023-08-04
公開日2024-05-08
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure and flexibility of the DNA polymerase holoenzyme of vaccinia virus.
Plos Pathog., 20, 2024
7B07
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BU of 7b07 by Molmil
TgoT_6G12 apo
分子名称: CALCIUM ION, DNA polymerase
著者Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M.
登録日2020-11-18
公開日2020-12-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.099 Å)
主引用文献Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution.
Biomolecules, 10, 2020
7B0G
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BU of 7b0g by Molmil
TgoT_6G12 binary with 2 hCTPs
分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(P*AP*TP*TP*GP*GP*CP*TP*GP*CP*CP*CP*TP*CP*C)-3'), DNA (5'-D(P*GP*GP*AP*GP*GP*GP*CP*AP*GP*()P*())-3'), ...
著者Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M.
登録日2020-11-19
公開日2020-12-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution.
Biomolecules, 10, 2020
7B0F
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BU of 7b0f by Molmil
TgoT_6G12 Binary complex
分子名称: DNA (5'-D(P*AP*AP*CP*GP*GP*CP*TP*AP*AP*TP*GP*CP*G)-3'), DNA (5'-D(P*CP*GP*CP*AP*TP*T)-3'), DNA polymerase, ...
著者Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M.
登録日2020-11-19
公開日2020-12-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.797 Å)
主引用文献Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution.
Biomolecules, 10, 2020
7B06
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TgoT_RT521 apo
分子名称: DNA polymerase
著者Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M.
登録日2020-11-18
公開日2020-12-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.349 Å)
主引用文献Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution.
Biomolecules, 10, 2020
1S5J
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BU of 1s5j by Molmil
Insight in DNA Replication: The crystal structure of DNA Polymerase B1 from the archaeon Sulfolobus solfataricus
分子名称: DNA polymerase I, MAGNESIUM ION, SULFATE ION
著者Savino, C, Federici, L, Nastopoulos, V, Johnson, K.A, Pisani, F.M, Rossi, M, Tsernoglou, D.
登録日2004-01-21
公開日2004-11-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Insights into DNA replication: the crystal structure of DNA polymerase B1 from the archaeon Sulfolobus solfataricus
Structure, 12, 2004
8TLT
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Cryo-EM structure of Rev1(deltaN)-Polzeta-DNA-dCTP complex
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*TP*AP*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*GP*AP*AP*T)-3'), ...
著者Malik, R, Aggarwal, A.K.
登録日2023-07-27
公開日2024-05-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Cryo-EM structure of the Rev1-Pol zeta holocomplex reveals the mechanism of their cooperativity in translesion DNA synthesis.
Nat.Struct.Mol.Biol., 2024
8TLQ
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Cryo-EM structure of the Rev1-Polzeta-DNA-dCTP complex
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (30-MER), ...
著者Malik, R, Aggarwal, A.K.
登録日2023-07-27
公開日2024-05-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Cryo-EM structure of the Rev1-Pol zeta holocomplex reveals the mechanism of their cooperativity in translesion DNA synthesis.
Nat.Struct.Mol.Biol., 2024

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件を2024-07-24に公開中

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