2GV9
 
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2JGU
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4M3W
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4M3Z
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4M41
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2DTU
 | | Crystal structure of the beta hairpin loop deletion variant of RB69 gp43 in complex with DNA containing an abasic site analog | | 分子名称: | 5'-D(*CP*GP*(3DR)P*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*GP*A)-3', DNA polymerase | | 著者 | Aller, P, Hogg, M, Konigsberg, W, Wallace, S.S, Doublie, S. | | 登録日 | 2006-07-15 | | 公開日 | 2006-12-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family.
J.Biol.Chem., 282, 2007
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4AIL
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4AHC
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4B08
 | | Yeast DNA polymerase alpha, Selenomethionine protein | | 分子名称: | DNA POLYMERASE ALPHA CATALYTIC SUBUNIT A | | 著者 | Perera, R.L, Torella, R, Klinge, S, Kilkenny, M.L, Maman, J.D, Pellegrini, L. | | 登録日 | 2012-06-29 | | 公開日 | 2013-02-27 | | 最終更新日 | 2013-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Mechanism for Priming DNA Synthesis by Yeast DNA Polymerase Alpha
Elife, 2, 2013
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7LXD
 | | Structure of yeast DNA Polymerase Zeta (apo) | | 分子名称: | DNA polymerase delta small subunit, DNA polymerase delta subunit 3, DNA polymerase zeta catalytic subunit, ... | | 著者 | Truong, C.D, Craig, T.A, Cui, G, Botuyan, M.V, Serkasevich, R.A, Chan, K.-Y, Mer, G, Chiu, P.-L, Kumar, R. | | 登録日 | 2021-03-03 | | 公開日 | 2021-06-30 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.11 Å) | | 主引用文献 | Cryo-EM reveals conformational flexibility in apo DNA polymerase zeta.
J.Biol.Chem., 297, 2021
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2ATQ
 | | RB69 single-stranded DNA binding protein-DNA polymerase fusion | | 分子名称: | DNA polymerase, GUANOSINE-5'-DIPHOSPHATE, ZINC ION, ... | | 著者 | Sun, S, Geng, L, Shamoo, Y. | | 登録日 | 2005-08-25 | | 公開日 | 2006-05-09 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure and enzymatic properties of a chimeric bacteriophage RB69 DNA polymerase and single-stranded DNA binding protein with increased processivity.
Proteins, 65, 2006
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7LUF
 | | HSV1 polymerase ternary complex with dsDNA and PNU-183792 | | 分子名称: | DNA (5'-D(*CP*GP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*TP*AP*C)-3'), DNA (5'-D(P*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*CP*G)-3'), DNA polymerase, ... | | 著者 | Hayes, R.P, Klein, D. | | 登録日 | 2021-02-22 | | 公開日 | 2021-04-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase.
Nat Commun, 12, 2021
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2DY4
 | | Crystal structure of RB69 GP43 in complex with DNA containing Thymine Glycol | | 分子名称: | 5'-D(*CP*GP*(CTG)P*GP*GP*AP*AP*TP*GP*A*CP*AP*GP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*CP*TP*GP*T*CP*AP*TP*TP*CP*CP*A)-3', DNA polymerase | | 著者 | Aller, P, Rould, M.A, Hogg, M, Wallace, S.S, Doublie, S. | | 登録日 | 2006-09-06 | | 公開日 | 2007-01-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol.
Proc.Natl.Acad.Sci.USA, 104, 2007
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7N2M
 | | Crystal structure of DNA polymerase alpha catalytic core in complex with dCTP and template/primer having T-C mismatch at the post-insertion site | | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*T*AP*GP*TP*CP*GP*CP*TP*CP*CP*AP*GP*GP*C)-3'), DNA polymerase alpha catalytic subunit, ... | | 著者 | Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. | | 登録日 | 2021-05-29 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural and functional insight into mismatch extension by human DNA polymerase alpha.
Proc.Natl.Acad.Sci.USA, 119, 2022
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1Q9X
 | | Crystal structure of Enterobacteria phage RB69 gp43 DNA polymerase complexed with tetrahydrofuran containing DNA | | 分子名称: | 1',2'-DIDEOXYRIBOFURANOSE-5'-PHOSPHATE, 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ... | | 著者 | Freisinger, E, Grollman, A.P, Miller, H, Kisker, C. | | 登録日 | 2003-08-26 | | 公開日 | 2004-04-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Lesion (in)tolerance reveals insights into DNA replication fidelity.
Embo J., 23, 2004
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1Q8I
 | | Crystal structure of ESCHERICHIA coli DNA Polymerase II | | 分子名称: | DNA polymerase II | | 著者 | Brunzelle, J.S, Muchmore, C.R.A, Mashhoon, N, Blair-Johnson, M, Shuvalova, L, Goodman, M.F, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2003-08-21 | | 公開日 | 2004-01-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of Escherichia Coli DNA Polymerase II
To be Published
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1QHT
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7RSU
 | | TNA polymerase, n+2 product | | 分子名称: | DNA polymerase, Primer, Template | | 著者 | Maola, V, Chaput, J, Chim, N. | | 登録日 | 2021-08-11 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Synthesis and Polymerase Recognition of Threose Nucleic Acid Triphosphates Equipped with Diverse Chemical Functionalities.
J.Am.Chem.Soc., 143, 2021
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1WN7
 | | Crystal structure of archaeal family B DNA polymerase mutant | | 分子名称: | Family B DNA Polymerase, GLYCEROL, NICKEL (II) ION | | 著者 | Kuroita, T, Matsumura, H, Yokota, N, Hashimoto, H, Imanaka, T, Inoue, T, Kai, Y. | | 登録日 | 2004-07-28 | | 公開日 | 2005-08-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural Mechanism for Coordination of Proofreading and Polymerase Activities in Archaeal DNA Polymerases
J.Mol.Biol., 351, 2005
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7S0T
 | | Structure of DNA polymerase zeta with mismatched DNA | | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (30-MER), ... | | 著者 | Malik, R, Ubarretxena, I.B, Aggarwal, A.K. | | 登録日 | 2021-08-31 | | 公開日 | 2022-03-09 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Cryo-EM structure of translesion DNA synthesis polymerase zeta with a base pair mismatch.
Nat Commun, 13, 2022
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1WNS
 | | Crystal structure of family B DNA polymerase from hyperthermophilic archaeon pyrococcus kodakaraensis KOD1 | | 分子名称: | DNA POLYMERASE | | 著者 | Hashimoto, H, Inoue, T, Kai, Y, Fujiwara, S, Takagi, M, Nishioka, M, Imanaka, T. | | 登録日 | 2004-08-09 | | 公開日 | 2004-08-17 | | 最終更新日 | 2017-08-16 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal Structure of DNA Polymerase from Hyperthermophilic Archaeon Pyrococcus Kodakaraensis Kod1
J.Mol.Biol., 306, 2001
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7RSS
 | | Kod-RI incorporating DNA, n+2 | | 分子名称: | DNA polymerase, Primer, Template | | 著者 | Hajjar, M, Chim, N, Chaput, J.C. | | 登録日 | 2021-08-11 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid.
Nucleic Acids Res., 50, 2022
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7RSR
 | | Kod-RI incorporating PMT, n+2 | | 分子名称: | DNA polymerase, Primer, Template | | 著者 | Hajjar, M, Chim, N, Chaput, J.C. | | 登録日 | 2021-08-11 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid.
Nucleic Acids Res., 50, 2022
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8D0K
 | | Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback template - PRIM2C advanced PIC | | 分子名称: | CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... | | 著者 | He, Q, Lin, X, Chavez, B.L, Agrawal, S, Lusk, B.L, Lim, C. | | 登録日 | 2022-05-26 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (4.27 Å) | | 主引用文献 | Structures of the human CST-Pol alpha-primase complex bound to telomere templates.
Nature, 608, 2022
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8D0B
 | | Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback template | | 分子名称: | CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... | | 著者 | He, Q, Lin, X, Chavez, B.L, Agrawal, S, Lusk, B.L, Lim, C. | | 登録日 | 2022-05-26 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.43 Å) | | 主引用文献 | Structures of the human CST-Pol alpha-primase complex bound to telomere templates.
Nature, 608, 2022
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