1R1L
 
 | | Structure of dimeric antithrombin complexed with a P14-P9 reactive loop peptide and an exogenous tripeptide (formyl-norleucine-LF) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin P14-P9 peptide, Antithrombin-III, ... | | 著者 | Zhou, A, Huntington, J.A, Lomas, D.A, Stein, P.E, Carrell, R.W. | | 登録日 | 2003-09-24 | | 公開日 | 2004-10-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Serpins and the design of peptides to block intermolecular beta-linkages
To be Published
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1OO8
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2XN6
 | | Crystal structure of thyroxine-binding globulin complexed with thyroxine-fluoresein | | 分子名称: | 1,2-ETHANEDIOL, 3',6'-DIHYDROXY-3-OXO-3H-SPIRO[2-BENZOFURAN-1,9'-XANTHENE]-6-CARBOXYLIC ACID, 3,5,3',5'-TETRAIODO-L-THYRONINE, ... | | 著者 | Qi, X, Yan, Y, Wei, Z, Zhou, A. | | 登録日 | 2010-07-30 | | 公開日 | 2011-02-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | | 主引用文献 | Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins.
J.Biol.Chem., 286, 2011
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2XN7
 | | Crystal structure of thyroxine-binding globulin complexed with thyroxine-fluoresein (T405-CF) | | 分子名称: | 1,2-ETHANEDIOL, 3',6'-DIHYDROXY-3-OXO-3H-SPIRO[2-BENZOFURAN-1,9'-XANTHENE]-5-CARBOXYLIC ACID, 3,5,3',5'-TETRAIODO-L-THYRONINE, ... | | 著者 | Qi, X, Yan, Y, Wei, Z, Zhou, A. | | 登録日 | 2010-07-30 | | 公開日 | 2011-02-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins.
J.Biol.Chem., 286, 2011
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2ZNH
 | | Crystal Structure of a Domain-Swapped Serpin Dimer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, ... | | 著者 | Yamasaki, M, Huntington, J.A. | | 登録日 | 2008-04-25 | | 公開日 | 2008-10-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of a stable dimer reveals the molecular basis of serpin polymerization
Nature, 455, 2008
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2XN5
 | | Crystal structure of thyroxine-binding globulin complexed with Furosemide | | 分子名称: | 1,2-ETHANEDIOL, 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, CALCIUM ION, ... | | 著者 | Qi, X, Yan, Y, Wei, Z, Zhou, A. | | 登録日 | 2010-07-30 | | 公開日 | 2011-02-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins.
J.Biol.Chem., 286, 2011
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2XN3
 | | Crystal structure of thyroxine-binding globulin complexed with mefenamic acid | | 分子名称: | 2-[(2,3-DIMETHYLPHENYL)AMINO]BENZOIC ACID, THYROXINE-BINDING GLOBULIN | | 著者 | Qi, X, Yan, Y, Wei, Z, Zhou, A. | | 登録日 | 2010-07-30 | | 公開日 | 2011-02-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins.
J.Biol.Chem., 286, 2011
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2WY1
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2WXY
 | | Crystal structure of mouse angiotensinogen in the reduced form | | 分子名称: | 1,2-ETHANEDIOL, ANGIOTENSINOGEN, SODIUM ION | | 著者 | Zhou, A, Wei, Z, Carrell, R.W, Read, R.J. | | 登録日 | 2009-11-11 | | 公開日 | 2010-10-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
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2ZV6
 | | Crystal structure of human squamous cell carcinoma antigen 1 | | 分子名称: | Serpin B3 | | 著者 | Zheng, B, Matoba, Y, Katagiri, C, Hibino, T, Sugiyama, M. | | 登録日 | 2008-11-01 | | 公開日 | 2009-02-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of SCCA1 and insight about the interaction with JNK1
Biochem.Biophys.Res.Commun., 380, 2009
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1OVA
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1SEK
 | | THE STRUCTURE OF ACTIVE SERPIN K FROM MANDUCA SEXTA AND A MODEL FOR SERPIN-PROTEASE COMPLEX FORMATION | | 分子名称: | SERPIN K | | 著者 | Li, J, Wang, Z, Canagarajah, B, Jiang, H, Kanost, M, Goldsmith, E.J. | | 登録日 | 1998-03-06 | | 公開日 | 1999-03-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The structure of active serpin 1K from Manduca sexta.
Structure Fold.Des., 7, 1999
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1SNG
 | | Structure of a Thermophilic Serpin in the Native State | | 分子名称: | COG4826: Serine protease inhibitor, SULFATE ION | | 著者 | Fulton, K.F, Buckle, A.M, Cabrita, L.D, Irving, J.A, Butcher, R.E, Smith, I, Reeve, S, Lesk, A.M, Bottomley, S.P, Rossjohn, J, Whisstock, J.C. | | 登録日 | 2004-03-10 | | 公開日 | 2004-12-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition.
J.Biol.Chem., 280, 2005
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1PSI
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1AZX
 | | ANTITHROMBIN/PENTASACCHARIDE COMPLEX | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, ANTITHROMBIN | | 著者 | Jin, L, Abrahams, J.P, Skinner, R, Petitou, M, Pike, R.N, Carrell, R.W. | | 登録日 | 1997-11-23 | | 公開日 | 1999-01-13 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The anticoagulant activation of antithrombin by heparin.
Proc.Natl.Acad.Sci.USA, 94, 1997
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1AS4
 | | CLEAVED ANTICHYMOTRYPSIN A349R | | 分子名称: | ACETATE ION, ANTICHYMOTRYPSIN | | 著者 | Lukacs, C.M, Christianson, D.W. | | 登録日 | 1997-08-12 | | 公開日 | 1998-02-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction.
Biochemistry, 37, 1998
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1BR8
 | | IMPLICATIONS FOR FUNCTION AND THERAPY OF A 2.9A STRUCTURE OF BINARY-COMPLEXED ANTITHROMBIN | | 分子名称: | PROTEIN (ANTITHROMBIN-III), PROTEIN (PEPTIDE) | | 著者 | Skinner, R, Chang, W.S.W, Jin, L, Pei, X.Y, Huntington, J.A, Abrahams, J.P, Carrell, R.W, Lomas, D.A. | | 登録日 | 1998-08-26 | | 公開日 | 1998-09-02 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Implications for function and therapy of a 2.9 A structure of binary-complexed antithrombin.
J.Mol.Biol., 283, 1998
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1D5S
 | | CRYSTAL STRUCTURE OF CLEAVED ANTITRYPSIN POLYMER | | 分子名称: | P1-ARG ANTITRYPSIN | | 著者 | Dunstone, M.A, Dai, W, Whisstock, J.C, Rossjohn, J, Pike, R.N, Feil, S.C, Le Bonneic, B.F, Parker, M.W, Bottomley, S.P. | | 登録日 | 1999-10-11 | | 公開日 | 2000-04-02 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Cleaved antitrypsin polymers at atomic resolution.
Protein Sci., 9, 2000
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1C8O
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1C5G
 | | PLASMINOGEN ACTIVATOR INHIBITOR-1 | | 分子名称: | PLASMINOGEN ACTIVATOR INHIBITOR-1 | | 著者 | Goldsmith, E.J. | | 登録日 | 1999-12-07 | | 公開日 | 1999-12-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Engineering of plasminogen activator inhibitor-1 to reduce the rate of latency transition.
Nat.Struct.Biol., 2, 1995
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1ATH
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1B3K
 | | Plasminogen activator inhibitor-1 | | 分子名称: | PLASMINOGEN ACTIVATOR INHIBITOR-1 | | 著者 | Sharp, A.M, Stein, P.E, Pannu, N.S, Read, R.J. | | 登録日 | 1998-12-11 | | 公開日 | 1999-12-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | The active conformation of plasminogen activator inhibitor 1, a target for drugs to control fibrinolysis and cell adhesion.
Structure Fold.Des., 7, 1999
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1ATU
 | | UNCLEAVED ALPHA-1-ANTITRYPSIN | | 分子名称: | ALPHA-1-ANTITRYPSIN | | 著者 | Ryu, S.-E, Choi, H.-J. | | 登録日 | 1997-05-11 | | 公開日 | 1997-08-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The native strains in the hydrophobic core and flexible reactive loop of a serine protease inhibitor: crystal structure of an uncleaved alpha1-antitrypsin at 2.7 A.
Structure, 4, 1996
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1DB2
 | | CRYSTAL STRUCTURE OF NATIVE PLASMINOGEN ACTIVATOR INHIBITOR-1 | | 分子名称: | PLASMINOGEN ACTIVATOR INHIBITOR-1 | | 著者 | Nar, H, Bauer, M, Stassen, J.M, Lang, D, Gils, A, Declerck, P. | | 登録日 | 1999-11-02 | | 公開日 | 1999-11-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation.
J.Mol.Biol., 297, 2000
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1ANT
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