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PDB: 515 件
2Z1G
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Crystal structure of E.coli RNase HI surface charged mutant(Q4R/T40E/Q72H/Q76K/Q80E/T92K/Q105K)
分子名称: Ribonuclease HI
著者You, D.J, Fukuchi, S, Nishikawa, K, Koga, Y, Takano, K, Kanaya, S.
登録日2007-05-08
公開日2007-11-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Protein Thermostabilization Requires a Fine-tuned Placement of Surface-charged Residues
J.Biochem.(Tokyo), 142, 2007
2Z1H
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Crystal structure of E.coli RNase HI surface charged mutant(Q4R/T92K/Q105K/Q113R/Q115K/N143K/T145K)
分子名称: Ribonuclease HI
著者You, D.J, Fukuchi, S, Nishikawa, K, Koga, Y, Takano, K, Kanaya, S.
登録日2007-05-08
公開日2007-11-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Protein Thermostabilization Requires a Fine-tuned Placement of Surface-charged Residues
J.Biochem.(Tokyo), 142, 2007
2ZQB
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Crystal structure of a psychrotrophic RNaseHI variant with sextuple thermostabilizing mutations
分子名称: Ribonuclease HI, SULFATE ION
著者Angkawidjaja, C, Kanaya, S.
登録日2008-08-07
公開日2009-06-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Destabilization of psychrotrophic RNase HI in a localized fashion as revealed by mutational and X-ray crystallographic analyses
Febs J., 276, 2009
3AA4
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A52V E.coli RNase HI
分子名称: Ribonuclease HI
著者Takano, K.
登録日2009-11-11
公開日2010-10-06
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Protein core adaptability: crystal structures of the cavity-filling variants of Escherichia coli RNase HI
Protein Pept.Lett., 17, 2010
3AA3
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A52L E. coli RNase HI
分子名称: Ribonuclease HI
著者Takano, K.
登録日2009-11-11
公開日2010-10-06
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Protein core adaptability: crystal structures of the cavity-filling variants of Escherichia coli RNase HI
Protein Pept.Lett., 17, 2010
3AA2
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A52I E. coli RNase HI
分子名称: Ribonuclease HI
著者Takano, K.
登録日2009-11-11
公開日2010-10-06
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Protein core adaptability: crystal structures of the cavity-filling variants of Escherichia coli RNase HI
Protein Pept.Lett., 17, 2010
3AA5
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A52F E.coli RNase HI
分子名称: Ribonuclease HI
著者Takano, K.
登録日2009-11-11
公開日2010-10-06
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Protein core adaptability: crystal structures of the cavity-filling variants of Escherichia coli RNase HI
Protein Pept.Lett., 17, 2010
1JL1
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D10A E. coli ribonuclease HI
分子名称: RIBONUCLEASE HI
著者Goedken, E.R, Marqusee, S.
登録日2001-07-13
公開日2002-02-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Native-state energetics of a thermostabilized variant of ribonuclease HI.
J.Mol.Biol., 314, 2001
1JXB
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I53A, a point mutant of the cysteine-free variant of E. coli Rnase HI
分子名称: Ribonuclease HI
著者Spudich, G, Lorenz, S, Marqusee, S.
登録日2001-09-06
公開日2002-03-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Propagation of a single destabilizing mutation throughout the Escherichia coli ribonuclease HI native state.
Protein Sci., 11, 2002
1JL2
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Crystal structure of TCEO RNase H-a chimera combining the folding core from T. thermophilus RNase H and the remaining region of E. coli RNase H
分子名称: Chimera of Ribonuclease HI, Ribonuclease H
著者Robic, S, Berger, J.M, Marqusee, S.
登録日2001-07-13
公開日2002-01-18
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Contributions of folding cores to the thermostabilities of two ribonucleases H.
Protein Sci., 11, 2002
1KVB
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E. COLI RIBONUCLEASE HI D134H MUTANT
分子名称: RIBONUCLEASE H
著者Kashiwagi, T, Jeanteur, D, Haruki, M, Katayanagi, K, Kanaya, S, Morikawa, K.
登録日1996-10-04
公開日1997-03-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Proposal for new catalytic roles for two invariant residues in Escherichia coli ribonuclease HI.
Protein Eng., 9, 1996
1KVA
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E. COLI RIBONUCLEASE HI D134A MUTANT
分子名称: RIBONUCLEASE H
著者Kashiwagi, T, Jeanteur, D, Haruki, M, Katayanagi, K, Kanaya, S, Morikawa, K.
登録日1996-10-04
公開日1997-03-12
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Proposal for new catalytic roles for two invariant residues in Escherichia coli ribonuclease HI.
Protein Eng., 9, 1996
1KVC
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E. COLI RIBONUCLEASE HI D134N MUTANT
分子名称: RIBONUCLEASE H
著者Kashiwagi, T, Jeanteur, D, Haruki, M, Katayanagi, K, Kanaya, S, Morikawa, K.
登録日1996-10-04
公開日1997-03-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Proposal for new catalytic roles for two invariant residues in Escherichia coli ribonuclease HI.
Protein Eng., 9, 1996
1LAW
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STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY CAVITY-FILLING MUTATIONS WITHIN A HYDROPHOBIC CORE
分子名称: RIBONUCLEASE H
著者Ishikawa, K, Nakamura, H, Morikawa, K, Kanaya, S.
登録日1993-05-10
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Stabilization of Escherichia coli ribonuclease HI by cavity-filling mutations within a hydrophobic core.
Biochemistry, 32, 1993
1LAV
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STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY CAVITY-FILLING MUTATIONS WITHIN A HYDROPHOBIC CORE
分子名称: RIBONUCLEASE H
著者Ishikawa, K, Nakamura, H, Morikawa, K, Kanaya, S.
登録日1993-05-10
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Stabilization of Escherichia coli ribonuclease HI by cavity-filling mutations within a hydrophobic core.
Biochemistry, 32, 1993
3H08
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Crystal structure of the Ribonuclease H1 from Chlorobium tepidum
分子名称: MAGNESIUM ION, Rnh (Ribonuclease H)
著者Ratcliff, K, Corn, J, Marqusee, S.
登録日2009-04-08
公開日2009-05-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure, stability, and folding of ribonuclease H1 from the moderately thermophilic chlorobium tepidum: comparison with thermophilic and mesophilic homologues.
Biochemistry, 48, 2009
3HYF
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Crystal structure of HIV-1 RNase H p15 with engineered E. coli loop and active site inhibitor
分子名称: 2-(3,4-dichlorobenzyl)-5,6-dihydroxypyrimidine-4-carboxylic acid, ACETATE ION, GLYCEROL, ...
著者Lansdon, E.B, Kirschberg, T.A.
登録日2009-06-22
公開日2009-10-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information.
J.Med.Chem., 52, 2009
3K2P
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HIV-1 Reverse Transcriptase Isolated RnaseH Domain with the Inhibitor beta-thujaplicinol Bound at the Active Site
分子名称: 2,7-dihydroxy-4-(propan-2-yl)cyclohepta-2,4,6-trien-1-one, MANGANESE (II) ION, Reverse Transcriptase
著者Pauly, T.A, Himmel, D.M, Maegley, K, Arnold, E.
登録日2009-09-30
公開日2010-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structure of HIV-1 reverse transcriptase with the inhibitor beta-Thujaplicinol bound at the RNase H active site.
Structure, 17, 2009
3LP3
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p15 HIV RNaseH domain with inhibitor MK3
分子名称: 3-[4-(diethylamino)phenoxy]-6-(ethoxycarbonyl)-5,8-dihydroxy-7-oxo-7,8-dihydro-1,8-naphthyridin-1-ium, MANGANESE (II) ION, p15
著者Yan, Y, Munshi, S.K, Prasad, G.S, Su, H.P.
登録日2010-02-04
公開日2010-06-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors.
J.Virol., 84, 2010
1O1W
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SOLUTION STRUCTURE OF THE RNASE H DOMAIN OF THE HIV-1 REVERSE TRANSCRIPTASE IN THE PRESENCE OF MAGNESIUM
分子名称: RIBONUCLEASE H
著者Pari, K, Mueller, G.A, Derose, E.F, Kirby, T.W, London, R.E.
登録日2003-02-12
公開日2003-02-18
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution Structure of the Rnase H Domain of the HIV-1 Reverse Transcriptase in the Presence of Magnesium
Biochemistry, 42, 2003
1RDB
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CRYSTAL STRUCTURES OF RIBONUCLEASE HI ACTIVE SITE MUTANTS FROM ESCHERICHIA COLI
分子名称: RIBONUCLEASE H
著者Katayanagi, K, Morikawa, K.
登録日1993-06-23
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of ribonuclease HI active site mutants from Escherichia coli.
J.Biol.Chem., 268, 1993
1RIL
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BU of 1ril by Molmil
CRYSTAL STRUCTURE OF RIBONUCLEASE H FROM THERMUS THERMOPHILUS HB8 REFINED AT 2.8 ANGSTROMS RESOLUTION
分子名称: RIBONUCLEASE H
著者Ishikawa, K, Okumura, M, Katayanagi, K, Kimura, S, Kanaya, S, Nakamura, H, Morikawa, K.
登録日1993-01-14
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of ribonuclease H from Thermus thermophilus HB8 refined at 2.8 A resolution.
J.Mol.Biol., 230, 1993
1RBS
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STRUCTURAL STUDY OF MUTANTS OF ESCHERICHIA COLI RIBONUCLEASE HI WITH ENHANCED THERMOSTABILITY
分子名称: RIBONUCLEASE H
著者Ishikawa, K, Kimura, S, Kanaya, S, Morikawa, K, Nakamura, H.
登録日1993-02-16
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural study of mutants of Escherichia coli ribonuclease HI with enhanced thermostability.
Protein Eng., 6, 1993
1RBU
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STRUCTURAL STUDY OF MUTANTS OF ESCHERICHIA COLI RIBONUCLEASE HI WITH ENHANCED THERMOSTABILITY
分子名称: RIBONUCLEASE H
著者Ishikawa, K, Kimura, S, Kanaya, S, Morikawa, K, Nakamura, H.
登録日1993-02-16
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural study of mutants of Escherichia coli ribonuclease HI with enhanced thermostability.
Protein Eng., 6, 1993
1RDH
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CRYSTALLOGRAPHIC ANALYSES OF AN ACTIVE HIV-1 RIBONUCLEASE H DOMAIN SHOW STRUCTURAL FEATURES THAT DISTINGUISH IT FROM THE INACTIVE FORM
分子名称: HIV-1 REVERSE TRANSCRIPTASE (RIBONUCLEASE H DOMAIN)
著者Finzel, B.C, Chattopadhyay, D, Einspahr, H.M.
登録日1993-03-05
公開日1994-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystallographic analyses of an active HIV-1 ribonuclease H domain show structural features that distinguish it from the inactive form.
Acta Crystallogr.,Sect.D, 49, 1993

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