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PDB: 1375 件

3NA1
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Crystal structure of human CYP11A1 in complex with 20-hydroxycholesterol
分子名称: (3alpha,8alpha)-cholest-5-ene-3,20-diol, Adrenodoxin, mitochondrial, ...
著者Strushkevich, N.V, MacKenzie, F, Tempel, W, Botchkarev, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J.U, Park, H, Structural Genomics Consortium (SGC)
登録日2010-05-31
公開日2011-06-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system.
Proc.Natl.Acad.Sci.USA, 108, 2011
3N9Y
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Crystal structure of human CYP11A1 in complex with cholesterol
分子名称: Adrenodoxin, CHOLESTEROL, Cholesterol side-chain cleavage enzyme, ...
著者Strushkevich, N.V, MacKenzie, F, Tempel, W, Botchkarev, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J.U, Park, H, Structural Genomics Consortium (SGC)
登録日2010-05-31
公開日2011-06-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system.
Proc.Natl.Acad.Sci.USA, 108, 2011
3N9Z
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BU of 3n9z by Molmil
Crystal structure of human CYP11A1 in complex with 22-hydroxycholesterol
分子名称: (3alpha,8alpha,22R)-cholest-5-ene-3,22-diol, Adrenodoxin, Cholesterol side-chain cleavage enzyme, ...
著者Strushkevich, N.V, MacKenzie, F, Tempel, W, Botchkarev, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J.U, Park, H, Structural Genomics Consortium (SGC)
登録日2010-05-31
公開日2011-06-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system.
Proc.Natl.Acad.Sci.USA, 108, 2011
4PWV
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BU of 4pwv by Molmil
Structure of P450sky (CYP163B3), a cytochrome P450 from skyllamycin biosynthesis in complex with a peptidyl carrier protein domain
分子名称: P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, Peptide synthetase, ...
著者Haslinger, K, Cryle, M.J.
登録日2014-03-21
公開日2014-07-23
最終更新日2014-08-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of a transient complex of a nonribosomal Peptide synthetase and a cytochrome p450 monooxygenase.
Angew.Chem.Int.Ed.Engl., 53, 2014
4PXH
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BU of 4pxh by Molmil
Structure of P450sky (CYP163B3), a cytochrome P450 from skyllamycin biosynthesis in complex with a peptidyl carrier protein domain
分子名称: P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, Peptide synthetase, ...
著者Haslinger, K, Cryle, M.J.
登録日2014-03-24
公開日2014-07-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structure of a transient complex of a nonribosomal Peptide synthetase and a cytochrome p450 monooxygenase.
Angew.Chem.Int.Ed.Engl., 53, 2014
7M8I
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BU of 7m8i by Molmil
Human CYP11B2 and human adrenodoxin in complex with fadrozole
分子名称: 4-[(5R)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl]benzonitrile, Adrenodoxin, Cytochrome P450 11B2, ...
著者Scott, E.E, Brixius-Anderko, S.
登録日2021-03-29
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Structural and functional insights into aldosterone synthase interaction with its redox partner protein adrenodoxin.
J.Biol.Chem., 296, 2021
2M56
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BU of 2m56 by Molmil
The structure of the complex of cytochrome P450cam and its electron donor putidaredoxin determined by paramagnetic NMR spectroscopy
分子名称: CAMPHOR, Camphor 5-monooxygenase, FE2/S2 (INORGANIC) CLUSTER, ...
著者Hiruma, Y, Hass, M.A.S, Ubbink, M.
登録日2013-02-14
公開日2013-08-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The structure of the cytochrome p450cam-putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography.
J.Mol.Biol., 425, 2013
4TX3
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BU of 4tx3 by Molmil
Complex of the X-domain and OxyB from Teicoplanin Biosynthesis
分子名称: 1,2-ETHANEDIOL, OxyB protein, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Peschke, M, Haslinger, K, Cryle, M.J.
登録日2014-07-02
公開日2015-02-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis.
Nature, 521, 2015
8AMQ
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BU of 8amq by Molmil
Crystal structure of the complex CYP143-FdxE from M. tuberculosis
分子名称: FE3-S4 CLUSTER, NICKEL (II) ION, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Bukhdruker, S, Varaksa, T, Smolskaya, S, Marin, E, Kapranov, I, Kovalev, K, Gilep, A, Strushkevich, N, Borshchevskiy, V.
登録日2022-08-03
公開日2023-02-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insights into 3Fe-4S ferredoxins diversity in M. tuberculosis highlighted by a first redox complex with P450.
Front Mol Biosci, 9, 2022
5GXG
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BU of 5gxg by Molmil
High-resolution crystal structure of the electron transfer complex of cytochrome p450cam with putidaredoxin
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Camphor 5-monooxygenase, FE2/S2 (INORGANIC) CLUSTER, ...
著者Kikui, Y, Hiruma, Y, Ubbink, M, Nojiri, M.
登録日2016-09-17
公開日2017-01-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Identification of productive and futile encounters in an electron transfer protein complex
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1BVY
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BU of 1bvy by Molmil
COMPLEX OF THE HEME AND FMN-BINDING DOMAINS OF THE CYTOCHROME P450(BM-3)
分子名称: 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, PROTEIN (CYTOCHROME P450 BM-3), ...
著者Sevrioukova, I.F, Li, H, Zhang, H, Peterson, J.A, Poulos, T.L.
登録日1998-09-21
公開日1999-02-23
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structure of a cytochrome P450-redox partner electron-transfer complex.
Proc.Natl.Acad.Sci.USA, 96, 1999
8DME
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BU of 8dme by Molmil
CYP102A1 in Open Conformation
分子名称: 6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole, Bifunctional cytochrome P450/NADPH--P450 reductase, FLAVIN MONONUCLEOTIDE, ...
著者Su, M, Xu, H.
登録日2022-07-08
公開日2023-07-19
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Insight into the conformational dynamics of cytochrome P450 CYP102A1 enzyme using Cryo-EM
To Be Published
8DMG
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BU of 8dmg by Molmil
CYP102A1 in Closed Conformation
分子名称: 6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole, Bifunctional cytochrome P450/NADPH--P450 reductase, FLAVIN MONONUCLEOTIDE, ...
著者Su, M, Xu, H.
登録日2022-07-08
公開日2023-07-19
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Insight into the conformational dynamics of cytochrome P450 CYP102A1 enzyme using Cryo-EM
To Be Published
3W9C
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BU of 3w9c by Molmil
Crystal structure of the electron transfer complex of cytochrome p450cam with putidaredoxin
分子名称: Camphor 5-monooxygenase, FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, ...
著者Kikui, Y, Hiruma, Y, Hass, M.A, Koteishi, H, Ubbink, M, Nojiri, M.
登録日2013-04-03
公開日2013-08-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of the cytochrome p450cam-putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography.
J.Mol.Biol., 425, 2013
6LAA
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BU of 6laa by Molmil
Crystal structure of full-length CYP116B46 from Tepidiphilus thermophilus
分子名称: 1,2-ETHANEDIOL, CARBONATE ION, Cytochrome P450, ...
著者Zhang, L.L, Ko, T.P, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T.
登録日2019-11-12
公開日2020-06-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural insight into the electron transfer pathway of a self-sufficient P450 monooxygenase.
Nat Commun, 11, 2020
6MCW
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BU of 6mcw by Molmil
Crystal structure of the P450 domain of the CYP51-ferredoxin fusion protein from Methylococcus capsulatus, complex with the detergent Anapoe-X-114
分子名称: 23-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]-3,6,9,12,15,18,21-heptaoxatricosan-1-ol, Cytochrome P450 51, PROTOPORPHYRIN IX CONTAINING FE
著者Hargrove, T, Wawrzak, Z, Lamb, D.C, Lepesheva, G.I.
登録日2018-09-02
公開日2019-07-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Concerning P450 evolution: Structural Analyses Support Bacterial Origin of Sterol 14 alpha-Demethylases.
Mol.Biol.Evol., 2020
6KBH
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BU of 6kbh by Molmil
Crystal structure of an intact type IV self-sufficient cytochrome P450 monooxygenase
分子名称: Cytochrome P450 monooxygenase, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
著者Gong, R, Wu, L.J, Zhang, Y, Liu, Z, Dou, S, Zhang, R.G, Xu, J.H, Tang, C, Zhou, J.H.
登録日2019-06-25
公開日2020-07-01
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of an intact type IV self-sufficient cytochrome P450 monooxygenase
To Be Published
7SNM
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BU of 7snm by Molmil
Lanosterol-bound P450 domain of the CYP51-ferredoxin fusion protein from Methylococcus capsulatus
分子名称: Cytochrome P450 51, LANOSTEROL, PROTOPORPHYRIN IX CONTAINING FE
著者Lepesheva, G.I, Hargrove, T, Wawrzak, Z.
登録日2021-10-28
公開日2022-10-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Unravelling the role of transient redox partner complexes in P450 electron transfer mechanics.
Sci Rep, 12, 2022
4JWU
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BU of 4jwu by Molmil
Crystal structure of Cytochrome P450cam-putidaredoxin complex
分子名称: 1,1'-hexane-1,6-diyldipyrrolidine-2,5-dione, CALCIUM ION, Camphor 5-monooxygenase, ...
著者Tripathi, S.M, Li, H, Poulos, T.L.
登録日2013-03-27
公開日2013-06-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for effector control and redox partner recognition in cytochrome P450.
Science, 340, 2013
4JX1
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BU of 4jx1 by Molmil
Crystal structure of reduced Cytochrome P450cam-putidaredoxin complex bound to camphor and 5-exo-hydroxycamphor
分子名称: 1,1'-hexane-1,6-diyldipyrrolidine-2,5-dione, 5-EXO-HYDROXYCAMPHOR, CALCIUM ION, ...
著者Tripathi, S.M, Li, H, Poulos, T.L.
登録日2013-03-27
公開日2013-06-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.087 Å)
主引用文献Structural basis for effector control and redox partner recognition in cytochrome P450.
Science, 340, 2013
4JWS
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BU of 4jws by Molmil
Crystal structure of Cytochrome P450cam-putidaredoxin complex
分子名称: 1,1'-hexane-1,6-diyldipyrrolidine-2,5-dione, CALCIUM ION, Camphor 5-monooxygenase, ...
著者Tripathi, S.M, Li, H, Poulos, T.L.
登録日2013-03-27
公開日2013-06-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis for effector control and redox partner recognition in cytochrome P450.
Science, 340, 2013
3EJE
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BU of 3eje by Molmil
Crystal Structure of P450BioI in complex with octadec-9Z-enoic acid ligated Acyl Carrier Protein
分子名称: Acyl carrier protein, Biotin biosynthesis cytochrome P450-like enzyme, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Cryle, M.J, Schlichting, I.
登録日2008-09-18
公開日2008-10-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3EJD
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BU of 3ejd by Molmil
Crystal Structure of P450BioI in complex with hexadec-9Z-enoic acid ligated Acyl Carrier Protein
分子名称: Acyl carrier protein, Biotin biosynthesis cytochrome P450-like enzyme, CHLORIDE ION, ...
著者Cryle, M.J, Schlichting, I.
登録日2008-09-18
公開日2008-10-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3EJB
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BU of 3ejb by Molmil
Crystal Structure of P450BioI in complex with tetradecanoic acid ligated Acyl Carrier Protein
分子名称: Acyl carrier protein, Biotin biosynthesis cytochrome P450-like enzyme, CHLORIDE ION, ...
著者Cryle, M.J, Schlichting, I.
登録日2008-09-18
公開日2008-10-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2YJN
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BU of 2yjn by Molmil
Structure of the glycosyltransferase EryCIII from the erythromycin biosynthetic pathway, in complex with its activating partner, EryCII
分子名称: DTDP-4-KETO-6-DEOXY-HEXOSE 3,4-ISOMERASE, GLYCOSYLTRANSFERASE
著者Moncrieffe, M.C, Fernandez, M.J, Spiteller, D, Matsumura, H, Gay, N.J, Luisi, B.F, Leadlay, P.F.
登録日2011-05-20
公開日2011-11-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.091 Å)
主引用文献Structure of the Glycosyltransferase Eryciii in Complex with its Activating P450 Homologue Erycii.
J.Mol.Biol., 415, 2012

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