3NA1
Crystal structure of human CYP11A1 in complex with 20-hydroxycholesterol
Summary for 3NA1
Entry DOI | 10.2210/pdb3na1/pdb |
Related | 3N9Y 3N9Z 3NA0 |
Descriptor | Cholesterol side-chain cleavage enzyme, mitochondrial, Adrenodoxin, mitochondrial, PROTOPORPHYRIN IX CONTAINING FE, ... (6 entities in total) |
Functional Keywords | cytochrome p450, 20-hydroxycholesterol, cholesterol side chain cleavage, structural genomics, structural genomics consortium, sgc, oxidoreductase, electron transport |
Biological source | Homo sapiens (human) More |
Cellular location | Mitochondrion membrane: P05108 Mitochondrion matrix : P10109 |
Total number of polymer chains | 4 |
Total formula weight | 143136.12 |
Authors | Strushkevich, N.V.,MacKenzie, F.,Tempel, W.,Botchkarev, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.U.,Park, H.,Structural Genomics Consortium (SGC) (deposition date: 2010-05-31, release date: 2011-06-08, Last modification date: 2023-09-06) |
Primary citation | Strushkevich, N.,Mackenzie, F.,Cherkesova, T.,Grabovec, I.,Usanov, S.,Park, H.W. Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system. Proc.Natl.Acad.Sci.USA, 108:10139-10143, 2011 Cited by PubMed: 21636783DOI: 10.1073/pnas.1019441108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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