3NA0

Crystal structure of human CYP11A1 in complex with 20,22-dihydroxycholesterol

Summary for 3NA0

Entry DOI	10.2210/pdb3na0/pdb
Related	3N9Y 3N9Z 3NA1
Descriptor	Cholesterol side-chain cleavage enzyme, mitochondrial, Adrenodoxin, mitochondrial, PROTOPORPHYRIN IX CONTAINING FE, ... (6 entities in total)
Functional Keywords	cytochrome p450, 20, 22-dihydroxycholesterol, side chain cleavage, structural genomics, structural genomics consortium, sgc, oxidoreductase, electron transport
Biological source	Homo sapiens (human) More
Cellular location	Mitochondrion membrane: P05108 Mitochondrion matrix : P10109
Total number of polymer chains	4
Total formula weight	127276.72
Authors	Strushkevich, N.V.,MacKenzie, F.,Tempel, W.,Botchkarev, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.U.,Park, H.,Structural Genomics Consortium (SGC) (deposition date: 2010-05-31, release date: 2010-09-08, Last modification date: 2024-02-21)
Primary citation	Strushkevich, N.,Mackenzie, F.,Cherkesova, T.,Grabovec, I.,Usanov, S.,Park, H.W. Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system. Proc.Natl.Acad.Sci.USA, 108:10139-10143, 2011 Cited by PubMed: 21636783 DOI: 10.1073/pnas.1019441108 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation