3NA0
Crystal structure of human CYP11A1 in complex with 20,22-dihydroxycholesterol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cholesterol side-chain cleavage enzyme, mitochondrial | polymer | 471 | 54911.0 | 2 | UniProt (P05108) Pfam (PF00067) | Homo sapiens (human) | Cytochrome P450 11A1, CYPXIA1, Cytochrome P450(scc), Cholesterol desmolase |
| 2 | C, D (C, D) | Adrenodoxin, mitochondrial | polymer | 68 | 7516.4 | 2 | UniProt (P10109) Pfam (PF00111) | Homo sapiens (human) | Adrenal ferredoxin, Ferredoxin-1, Hepatoredoxin |
| 3 | E, G (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 4 | F, H (A, B) | (3alpha,8alpha,22R)-cholest-5-ene-3,20,22-triol | non-polymer | 418.7 | 2 | Chemie (2DC) PubChem (24774749) PubChem (24776126) PubChem (53477897) PubChem (53932489) PubChem (53932490) PubChem (53932491) PubChem (59184514) PubChem (5118785) PubChem (68237552) PubChem (68237555) PubChem (67145493) PubChem (70802376) PubChem (70918336) PubChem (70918337) PubChem (71086287) PubChem (90305298) PubChem (9802154) PubChem (71777104) PubChem (15542296) PubChem (6453841) PubChem (125181300) PubChem (124225487) PubChem (124225488) PubChem (124483549) PubChem (124483550) PubChem (129060747) PubChem (129191190) PubChem (129191261) PubChem (129715149) PubChem (131668596) PubChem (131700532) PubChem (137451341) PubChem (146346626) PubChem (163291814) PubChem (163658219) PubChem (167063733) PubChem (171035483) | |||
| 5 | I, J (C, D) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 6 | K, L, M (A, B, D) | water | water | 18.0 | 291 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 124854.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2421.9 | |
| All* | Total formula weight | 127276.7 |
