4PXH

Structure of P450sky (CYP163B3), a cytochrome P450 from skyllamycin biosynthesis in complex with a peptidyl carrier protein domain

Summary for 4PXH

Entry DOI	10.2210/pdb4pxh/pdb
Related	4L0E 4L0F 4PWV
Descriptor	P450 monooxygenase, Peptide synthetase, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total)
Functional Keywords	cytochrome p450 fold, beta-aminoacyl carrier protein hydroxylase, peptidyl carrier protein domains, skyllamycin nrps, oxidoreductase-protein binding complex, oxidoreductase/protein binding
Biological source	Streptomyces sp. Acta 2897 More
Total number of polymer chains	6
Total formula weight	181873.65
Authors	Haslinger, K.,Cryle, M.J. (deposition date: 2014-03-24, release date: 2014-07-23, Last modification date: 2023-09-20)
Primary citation	Haslinger, K.,Brieke, C.,Uhlmann, S.,Sieverling, L.,Sussmuth, R.D.,Cryle, M.J. The structure of a transient complex of a nonribosomal Peptide synthetase and a cytochrome p450 monooxygenase. Angew.Chem.Int.Ed.Engl., 53:8518-8522, 2014 Cited by PubMed: 25044735 DOI: 10.1002/anie.201404977 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation