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PDB: 523 件
7PVZ
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Crystal structure of the intertwined dimer of the c-Src SH3 domain E93V-S94A-R95S-T96G mutant
分子名称: Isoform 2 of Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A, Salinas Garcia, M.C.
登録日2021-10-05
公開日2022-11-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The effect of the hinge loops composition in the domain swapping of the SH3 domain
To be published
7S4R
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Serial Macromolecular Crystallography at ALBA Synchrotron Light Source - alpha Spectrin-SH3 domain
分子名称: Spectrin alpha chain, non-erythrocytic 1
著者Martin-Garcia, J.M, Botha, S, Hu, H, Jernigan, R, Castellvi, A, Lisova, S, Gil, F, Calisto, B, Crespo, I, Roy-Chowdbury, S, Grieco, A, Ketawala, G, Weierstall, U, Spence, J, Fromme, P, Zatsepin, N, Boer, R, Carpena, X.
登録日2021-09-09
公開日2021-10-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Serial macromolecular crystallography at ALBA Synchrotron Light Source.
J.Synchrotron Radiat., 29, 2022
5NP3
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Abl2 SH3
分子名称: Abelson tyrosine-protein kinase 2
著者Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
登録日2017-04-13
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
5NP5
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Abl2 SH3 pTyr116/161
分子名称: Abelson tyrosine-protein kinase 2, SULFATE ION
著者Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
登録日2017-04-13
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
5O2P
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p130Cas SH3 domain PTP-PEST peptide chimera
分子名称: Breast cancer anti-estrogen resistance 1,Tyrosine-protein phosphatase non-receptor type 12
著者Hexnerova, R, Veverka, V.
登録日2017-05-22
公開日2017-09-20
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.
Sci Rep, 7, 2017
5OAZ
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Crystal structure of the Abl-SH3 domain at pH 7.5
分子名称: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1
著者Camara-Artigas, A.
登録日2017-06-25
公開日2017-07-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.03 Å)
主引用文献Crystal structure of the Abl-SH3 domain at pH 7.5
to be published
5O2M
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p130Cas SH3 domain
分子名称: Breast cancer anti-estrogen resistance 1
著者Hexnerova, R, Veverka, V.
登録日2017-05-22
公開日2017-09-20
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.
Sci Rep, 7, 2017
5NP2
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Abl1 SH3 pTyr89/134
分子名称: Tyrosine-protein kinase ABL1
著者Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
登録日2017-04-13
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
5OB2
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Crystal structure of the c-Src-SH3 domain E97T mutant in complex with the high affinity peptide APP12
分子名称: APP12, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A.
登録日2017-06-25
公開日2017-07-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the c-Src-SH3 domain E97T mutant in complex with the high affinity peptide APP12
to be published
5OB0
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Crystal structure of the c-Src-SH3 domain Q128E mutant in complex with the high affinity peptide APP12
分子名称: APP12, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION
著者Camara-Artigas, A.
登録日2017-06-25
公開日2017-07-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.172 Å)
主引用文献Crystal structure of the c-Src-SH3 domain Q128E mutant in complex with the high affinity peptide APP12
to be published
5OAV
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High resolution crystal structure of the c-Src-SH3 domain mutant E93V in complex with the high affinity synthetic peptide APP12: monoclinic crystal
分子名称: APP12, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A.
登録日2017-06-23
公開日2017-07-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献High resolution crystal structure of the c-Src-SH3 domain mutant E93V in complex with the high affinity synthetic peptide APP12: monoclinic crystal
to be published
5OB1
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Crystal structure of the c-Src-SH3 domain Q128R mutant in complex with the high affinity peptide APP12
分子名称: APP12, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A.
登録日2017-06-25
公開日2017-07-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.172 Å)
主引用文献Crystal structure of the c-Src-SH3 domain Q128R mutant in complex with the high affinity peptide APP12
to be published
5O2Q
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p130Cas SH3 domain Vinculin peptide chimera
分子名称: Breast cancer anti-estrogen resistance 1,Vinculin
著者Hexnerova, R, Veverka, V.
登録日2017-05-22
公開日2017-09-20
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.
Sci Rep, 7, 2017
2RNA
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Itk SH3 average minimized
分子名称: Tyrosine-protein kinase ITK/TSK
著者Severin, A.J.
登録日2007-12-08
公開日2007-12-25
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献NMR structure note: murine Itk SH3 domain
To be Published
2RMO
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Solution structure of alpha-spectrin_SH3-bergerac from Chicken
分子名称: Spectrin alpha chain, brain
著者Kutyshenko, V.P, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, Y.A, Fedyukina, D.V, Gushchina, L.V, Khristoforov, V.S, Filimonov, V.V.
登録日2007-11-07
公開日2008-09-30
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Study of the structure and dynamics of a chimeric variant of the SH3 domain (SHA-Bergerac) by NMR spectroscopy
Russ.J.Bioorganic Chem., 34, 2008
5FW9
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Human Spectrin SH3 domain D48G, E7Y, K60Y
分子名称: SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1
著者Gallego, P, Navarro, S, Ventura, S, Reverter, D.
登録日2016-02-12
公開日2016-12-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Human Spectrin SH3 Domain D48G, E7Y, K60Y
To be Published
2RQV
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BU of 2rqv by Molmil
Solution structure of SH3CI domain of Bem1p
分子名称: Bud emergence protein 1
著者Takaku, T, Ogura, K, Inagaki, F.
登録日2009-12-21
公開日2010-04-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of a novel Cdc42-binding module of Bem1 and its interaction with Ste20 and Cdc42
J.Biol.Chem., 285, 2010
5FWC
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BU of 5fwc by Molmil
Human Spectrin SH3 domain D48G, E7A, K60A
分子名称: 1,2-ETHANEDIOL, AMMONIUM ION, SPECTRIN ALPHA CHAIN, ...
著者Gallego, P, Navarro, S, Ventura, S, Reverter, D.
登録日2016-02-12
公開日2016-12-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Human Spectrin SH3 Domain D48G, E7A, K60A
To be Published
5FWB
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Human Spectrin SH3 domain D48G, E7F, K60F
分子名称: SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1
著者Gallego, P, Navarro, S, Ventura, S, Reverter, D.
登録日2016-02-12
公開日2016-12-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Human Spectrin SH3 Domain D48G, E7F, K60F
To be Published
2RQW
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BU of 2rqw by Molmil
Solution structure of Bem1p SH3CI domain complexed with Ste20p-PRR peptide
分子名称: 24-meric peptide from Serine/threonine-protein kinase STE20, Bud emergence protein 1
著者Takaku, T, Ogura, K, Inagaki, F.
登録日2009-12-21
公開日2010-04-21
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of a novel Cdc42-binding module of Bem1 and its interaction with Ste20 and Cdc42
J.Biol.Chem., 285, 2010
2RPN
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A crucial role for high intrinsic specificity in the function of yeast SH3 domains
分子名称: Actin-binding protein, Actin-regulating kinase 1
著者Stollar, E.J, Garcia, B, Chong, A, Forman-Kay, J, Davidson, A.
登録日2008-06-12
公開日2009-06-16
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p
J.Biol.Chem., 284, 2009
2SEM
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BU of 2sem by Molmil
SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR
分子名称: PROTEIN (SEX MUSCLE ABNORMAL PROTEIN 5), PROTEIN (SH3 PEPTOID INHIBITOR)
著者Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A.
登録日1998-11-02
公開日1999-01-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors.
Science, 282, 1998
1GCQ
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BU of 1gcq by Molmil
CRYSTAL STRUCTURE OF VAV AND GRB2 SH3 DOMAINS
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, VAV PROTO-ONCOGENE
著者Nishida, M, Nagata, K, Hachimori, Y, Ogura, K, Inagaki, F.
登録日2000-08-08
公開日2001-08-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Novel recognition mode between Vav and Grb2 SH3 domains.
EMBO J., 20, 2001
1GFD
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SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE C-TERMINAL SH3 DOMAIN OF GRB2
分子名称: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
著者Kohda, D, Terasawa, H, Hatanaka, H, Inagaki, F.
登録日1994-06-13
公開日1994-08-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2.
Structure, 2, 1994
1GBQ
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SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE
分子名称: GRB2, SOS-1
著者Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L.
登録日1996-12-23
公開日1997-09-04
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
J.Mol.Biol., 267, 1997

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