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PDB: 533 件
7NZC
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First SH3 domain of POSH (Plenty of SH3 Domains protein)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, E3 ubiquitin-protein ligase SH3RF1
著者Palencia, A, Bessa, L.M, Jensen, M.R.
登録日2021-03-23
公開日2021-12-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.111 Å)
主引用文献Visualizing protein breathing motions associated with aromatic ring flipping.
Nature, 602, 2022
6NMW
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BU of 6nmw by Molmil
Crystal structure of the human Lyn SH3 domain
分子名称: Tyrosine-protein kinase Lyn
著者Berndt, S, Gurevich, V.V, Iverson, T.M.
登録日2019-01-12
公開日2019-04-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.199 Å)
主引用文献Crystal structure of the SH3 domain of human Lyn non-receptor tyrosine kinase.
PLoS ONE, 14, 2019
5EC7
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Crystal structure of a chimeric c-Src-SH3 domain with the sequence of the RT-loop from the Abl-SH3 domain at pH 5.0
分子名称: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A.
登録日2015-10-20
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of a chimeric c-Src-SH3 domain with the sequence of the RT-loop from the Abl-SH3 domain at pH 5.0
to be published
7JT9
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BU of 7jt9 by Molmil
Fgr SH3 domain crystal structure
分子名称: Tyrosine-protein kinase Fgr
著者Perez, I, Berndt, S, Gurevich, V.V, Iverson, T.M.
登録日2020-08-17
公開日2022-01-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献A Model for the Signal Initiation Complex Between Arrestin-3 and the Src Family Kinase Fgr.
J.Mol.Biol., 434, 2022
5ZAU
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BU of 5zau by Molmil
Complex of the human FYN SH3 and monobody binder
分子名称: Monobody Binder, Tyrosine-protein kinase Fyn
著者Reddy, P.P, Gulyani, A, Das, R.
登録日2018-02-09
公開日2019-09-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A Fyn biosensor reveals pulsatile, spatially localized kinase activity and signaling crosstalk in live mammalian cells.
Elife, 9, 2020
6A9C
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BU of 6a9c by Molmil
Crystal Structure c-terminal SH3 domain of Myosin IB from Entamoeba histolytica bound to EhFP10(GEF) peptide.
分子名称: Peptide from Rho guanine nucleotide exchange factor, SULFATE ION, Unconventional myosin IB
著者Gautam, G, Gourinath, S.
登録日2018-07-13
公開日2019-06-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献EhFP10: A FYVE family GEF interacts with myosin IB to regulate cytoskeletal dynamics during endocytosis in Entamoeba histolytica.
Plos Pathog., 15, 2019
5HCK
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BU of 5hck by Molmil
HUMAN HCK SH3 DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: HEMATOPOIETIC CELL KINASE
著者Horita, D.A, Baldisseri, D.M, Zhang, W, Altieri, A.S, Smithgall, T.E, Gmeiner, W.H, Byrd, R.A.
登録日1998-03-09
公開日1998-06-17
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the human Hck SH3 domain and identification of its ligand binding site.
J.Mol.Biol., 278, 1998
5I11
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Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain T114S-Q128R mutant
分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, ...
著者Camara-Artigas, A.
登録日2016-02-05
公開日2016-03-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain T114S-Q128R mutant
To Be Published
6EDF
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Fragment of a tyrosine-protein kinase
分子名称: FYN, GLYCEROL, UNKNOWN ATOM OR ION
著者Tempel, W, Huang, H, Sochirca, I, Liu, K, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Sidhu, S.S, Min, J, Structural Genomics Consortium (SGC)
登録日2018-08-09
公開日2018-08-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Fragment of a tyrosine-protein kinase
To be Published
5UL6
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The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions
分子名称: Adapter molecule crk, Proline-rich motif of nonstructural protein 1 of influenza a virus
著者Shen, Q, Zeng, D, Zhao, B, Li, P, Cho, J.H.
登録日2017-01-24
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The Molecular Mechanisms Underlying the Hijack of Host Proteins by the 1918 Spanish Influenza Virus.
ACS Chem. Biol., 12, 2017
3C0C
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BU of 3c0c by Molmil
X-ray Crystal Structure of the Rat Endophilin A2 SH3 Domain
分子名称: Endophilin-A2
著者Loll, P.J, Swain, E.
登録日2008-01-19
公開日2008-03-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the SH3 domain of rat endophilin A2
To be Published
5VEI
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Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
分子名称: Sorbin and SH3 domain-containing protein 2, UNKNOWN ATOM OR ION
著者Liu, Y, Tempel, W, Huang, H, Gu, J, Liu, K, Sidhu, S.S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-04-04
公開日2017-08-02
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
To be Published
3CQT
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BU of 3cqt by Molmil
N53I V55L MUTANT of FYN SH3 DOMAIN
分子名称: Proto-oncogene tyrosine-protein kinase Fyn
著者Neculai, A.M, Zarrine-Afsar, A, Howell, P.L, Davidson, A, Chan, H.S.
登録日2008-04-03
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Theoretical and experimental demonstration of the importance of specific nonnative interactions in protein folding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
5XGG
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BU of 5xgg by Molmil
Crystal Structure C-terminal SH3 domain of Myosin IB from Entamoeba histolytica
分子名称: SULFATE ION, Unconventional myosin IB
著者Gautam, G, Gourinath, S.
登録日2017-04-13
公開日2017-08-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Crystal structure of the PEG-bound SH3 domain of myosin IB from Entamoeba histolytica reveals its mode of ligand recognition
Acta Crystallogr D Struct Biol, 73, 2017
3IQL
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BU of 3iql by Molmil
Crystal structure of the rat endophilin-A1 SH3 domain
分子名称: CHLORIDE ION, Endophilin-A1
著者Trempe, J.F, Kozlov, G, Camacho, E.M, Gehring, K.
登録日2009-08-20
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination.
Mol.Cell, 36, 2009
3I9Q
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Crystal Structure of the triple mutant S19G-P20D-R21S of alpha spectrin SH3 domain
分子名称: SULFATE ION, Spectrin alpha chain
著者Camara-Artigas, A, Gavira, J.A.
登録日2009-07-12
公開日2009-12-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The effect of a proline residue on the rate of growth and the space group of alpha-spectrin SH3-domain crystals.
Acta Crystallogr.,Sect.D, 65, 2009
6IPY
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BU of 6ipy by Molmil
His-tagged Fyn SH3 domain R96I mutant
分子名称: Tyrosine-protein kinase Fyn
著者Arold, S.T, Aljedani, S.S, Shahul Hameed, U.F.
登録日2018-11-05
公開日2018-11-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.343 Å)
主引用文献Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
6SCW
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BU of 6scw by Molmil
SH3-subunit of chicken alpha spectrin solved by NMR
分子名称: Spectrin alpha chain, non-erythrocytic 1 isoform X11
著者Grohe, K, Hebrank, C, Linser, R.
登録日2019-07-25
公開日2020-08-12
最終更新日2024-01-31
実験手法SOLUTION NMR
主引用文献Protein Motional Details Revealed by Complementary Structural Biology Techniques.
Structure, 28, 2020
6SDF
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BU of 6sdf by Molmil
N-terminal SH3 domain of Grb2 protein
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Growth factor receptor-bound protein 2
著者Bolgov, A.A, Korban, S.A, Luzik, D.A, Rogacheva, O.N, Zhemkov, V.A, Kim, M, Skrynnikov, N.R, Bezprozvanny, I.B.
登録日2019-07-26
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the SH3 domain of growth factor receptor-bound protein 2.
Acta Crystallogr.,Sect.F, 76, 2020
5XG9
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Crystal Structure of PEG-bound SH3 domain of Myosin IB from Entamoeba histolytica
分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, PENTAETHYLENE GLYCOL, ...
著者Gautam, G, Gourinath, S.
登録日2017-04-13
公開日2017-08-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal structure of the PEG-bound SH3 domain of myosin IB from Entamoeba histolytica reveals its mode of ligand recognition
Acta Crystallogr D Struct Biol, 73, 2017
4Y92
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Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain E97T-Q128R mutant
分子名称: GLYCEROL, Protein-tyrosine kinase, SULFATE ION, ...
著者Camara-Artigas, A, Bacarizo, J.
登録日2015-02-16
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain E97T-Q128R mutant
to be published
4ZNX
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Crystal structure of the Fyn-SH3 domain in complex with the high affinity peptide APP12
分子名称: APP12, Tyrosine-protein kinase Fyn
著者Camara-Artigas, A.
登録日2015-05-05
公開日2016-06-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The role of water molecules in the binding of class I and II peptides to the SH3 domain of the Fyn tyrosine kinase.
Acta Crystallogr.,Sect.F, 72, 2016
6IPZ
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Fyn SH3 domain R96W mutant, crystallized with 18-crown-6
分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Tyrosine-protein kinase Fyn
著者Arold, S.T, Aljedani, S.S, Shahul Hameed, U.F.
登録日2018-11-05
公開日2018-11-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.576 Å)
主引用文献Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
7NER
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BU of 7ner by Molmil
Crystal structure of the v-Src SH3 domain Q128R mutant
分子名称: SULFATE ION, TETRAETHYLENE GLYCOL, v-Src SH3 domain
著者Camara-Artigas, A, Salinas-Garcia, M.C.
登録日2021-02-04
公開日2021-06-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain.
Acta Crystallogr D Struct Biol, 77, 2021
7NET
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Crystal structure of the v-Src SH3 domain W95R-I96T mutant
分子名称: DI(HYDROXYETHYL)ETHER, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Camara-Artigas, A, Salinas-Garcia, M.C.
登録日2021-02-04
公開日2021-06-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain.
Acta Crystallogr D Struct Biol, 77, 2021

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