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PDB: 666 件

6LQV
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Cryo-EM structure of 90S small subunit preribosomes in transition states (State C1)
分子名称: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S11-A, ...
著者Du, Y, Ye, K.
登録日2020-01-14
公開日2020-09-16
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Science, 369, 2020
6LQT
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BU of 6lqt by Molmil
Cryo-EM structure of 90S small subunit preribosomes in transition states (State E)
分子名称: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S1-A, ...
著者Du, Y, Ye, K.
登録日2020-01-14
公開日2020-09-16
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Science, 369, 2020
6LQQ
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BU of 6lqq by Molmil
Cryo-EM structure of 90S small subunit preribosomes in transition states (State B)
分子名称: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S1-A, ...
著者Du, Y, Ye, K.
登録日2020-01-14
公開日2020-09-16
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Science, 369, 2020
6MDO
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BU of 6mdo by Molmil
The D1 and D2 domain rings of NSF engaging the SNAP-25 N-terminus within the 20S supercomplex (focused refinement on D1/D2 rings, class 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Synaptosomal-associated protein 25, ...
著者White, K.I, Zhao, M, Brunger, A.T.
登録日2018-09-04
公開日2018-09-19
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural principles of SNARE complex recognition by the AAA+ protein NSF.
Elife, 7, 2018
6LQP
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BU of 6lqp by Molmil
Cryo-EM structure of 90S small subunit preribosomes in transition states (State A)
分子名称: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S1-A, ...
著者Du, Y, Ye, K.
登録日2020-01-14
公開日2020-09-16
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Science, 369, 2020
6LQU
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BU of 6lqu by Molmil
Cryo-EM structure of 90S small subunit preribosomes in transition states (State A1)
分子名称: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S11-A, ...
著者Du, Y, Ye, K.
登録日2020-01-14
公開日2020-09-16
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Science, 369, 2020
6MAT
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BU of 6mat by Molmil
Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Rix7 mutant, unknown protein
著者Lo, Y.H, Sobhany, M, Hsu, A.L, Ford, B.L, Krahn, J.M, Borgnia, M.J, Stanley, R.E.
登録日2018-08-28
公開日2019-02-06
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7.
Nat Commun, 10, 2019
6MDN
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BU of 6mdn by Molmil
The 20S supercomplex engaging the SNAP-25 N-terminus (class 2)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Alpha-soluble NSF attachment protein, ...
著者White, K.I, Zhao, M, Brunger, A.T.
登録日2018-09-04
公開日2018-09-19
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural principles of SNARE complex recognition by the AAA+ protein NSF.
Elife, 7, 2018
6MDM
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BU of 6mdm by Molmil
The 20S supercomplex engaging the SNAP-25 N-terminus (class 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Alpha-soluble NSF attachment protein, ...
著者White, K.I, Zhao, M, Brunger, A.T.
登録日2018-09-04
公開日2018-09-19
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural principles of SNARE complex recognition by the AAA+ protein NSF.
Elife, 7, 2018
6MCK
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BU of 6mck by Molmil
p97 D1D2 with CB5083 bound
分子名称: 1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide, Transitional endoplasmic reticulum ATPase
著者Xia, D, Tang, W.K.
登録日2018-08-31
公開日2019-01-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.77 Å)
主引用文献Structural Basis of p97 Inhibition by the Site-Selective Anticancer Compound CB-5083.
Mol. Pharmacol., 95, 2019
6MSJ
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BU of 6msj by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-11-21
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
6MSG
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BU of 6msg by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-11-21
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
6MSE
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BU of 6mse by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-11-21
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
6N8V
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BU of 6n8v by Molmil
Hsp104DWB open conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 104
著者Lee, S, Rho, S.H, Lee, J, Sung, N, Liu, J, Tsai, F.T.F.
登録日2018-11-30
公開日2019-01-02
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (9.3 Å)
主引用文献Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation.
Cell Rep, 26, 2019
6MSB
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BU of 6msb by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-12-05
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
6MSK
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BU of 6msk by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-11-21
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
6MSH
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BU of 6msh by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-11-21
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
6NYV
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BU of 6nyv by Molmil
Structure of spastin AAA domain in complex with a quinazoline-based inhibitor
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, N-(3-tert-butyl-1H-pyrazol-5-yl)-2-[(2R)-2-methylpiperazin-1-yl]quinazolin-4-amine, SULFATE ION, ...
著者Pisa, R, Cupido, T, Kapoor, T.M.
登録日2019-02-12
公開日2019-03-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.425 Å)
主引用文献Designing Allele-Specific Inhibitors of Spastin, a Microtubule-Severing AAA Protein.
J. Am. Chem. Soc., 141, 2019
6NYY
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BU of 6nyy by Molmil
human m-AAA protease AFG3L2, substrate-bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, AFG3-like protein 2, MAGNESIUM ION, ...
著者Lander, G.C, Puchades, C.
登録日2019-02-12
公開日2019-05-22
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Unique Structural Features of the Mitochondrial AAA+ Protease AFG3L2 Reveal the Molecular Basis for Activity in Health and Disease.
Mol.Cell, 75, 2019
6NDY
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BU of 6ndy by Molmil
Vps4 with Cyclic Peptide Bound in the Central Pore
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Designed Cyclic Peptide, ...
著者Han, H, Fulcher, J.M, Dandey, V.P, Sundquist, W.I, Kay, M.S, Shen, P, Hill, C.P.
登録日2018-12-14
公開日2019-08-21
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of Vps4 with circular peptides and implications for translocation of two polypeptide chains by AAA+ ATPases.
Elife, 8, 2019
6NYW
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BU of 6nyw by Molmil
Structure of spastin AAA domain N527C mutant in complex with 8-fluoroquinazoline-based inhibitor
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, N-(5-tert-butyl-1H-pyrazol-3-yl)-8-fluoro-2-[(2R)-2-methylpiperazin-1-yl]quinazolin-4-amine, ...
著者Pisa, R, Cupido, T, Kapoor, T.M.
登録日2019-02-12
公開日2019-03-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.189 Å)
主引用文献Designing Allele-Specific Inhibitors of Spastin, a Microtubule-Severing AAA Protein.
J. Am. Chem. Soc., 141, 2019
6MSD
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BU of 6msd by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-12-05
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
6N8T
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BU of 6n8t by Molmil
Hsp104DWB closed conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 104
著者Lee, S, Rho, S.H, Lee, J, Sung, N, Liu, J, Tsai, F.T.F.
登録日2018-11-30
公開日2019-01-02
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation.
Cell Rep, 26, 2019
6OA9
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Cdc48-Npl4 complex processing poly-ubiquitinated substrate in the presence of ATP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
著者Twomey, E.C, Ji, Z, Wales, T.E, Bodnar, N.O, Engen, J.R, Rapoport, T.A.
登録日2019-03-15
公開日2019-07-03
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding.
Science, 365, 2019
6OMB
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BU of 6omb by Molmil
Cdc48 Hexamer (Subunits A to E) with substrate bound to the central pore
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 48, ...
著者Cooney, I, Han, H, Stewart, M, Carson, R.H, Hansen, D, Price, J.C, Hill, C.P, Shen, P.S.
登録日2019-04-18
公開日2019-07-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of the Cdc48 segregase in the act of unfolding an authentic substrate.
Science, 365, 2019

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