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PDB: 64 件
5UH7
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BU of 5uh7 by Molmil
Crystal structure of beta'MtbSI of Mycobacterium tuberculosis RNA polymerase
分子名称: DNA-directed RNA polymerase subunit beta'
著者Lin, W, Das, K, Feng, Y, Ebright, R.H.
登録日2017-01-11
公開日2017-04-12
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
7KIN
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BU of 7kin by Molmil
Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 promoter
分子名称: DNA (49-MER), DNA (54-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Lilic, M, Darst, S.A, Campbell, E.A.
登録日2020-10-23
公開日2021-04-21
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7.
Mol.Cell, 81, 2021
5ZX3
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BU of 5zx3 by Molmil
Mycobacterium tuberculosis RNA polymerase holoenzyme with ECF sigma factor sigma H
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Li, L, Zhang, Y.
登録日2018-05-17
公開日2019-03-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.751 Å)
主引用文献Structural basis for transcription initiation by bacterial ECF sigma factors.
Nat Commun, 10, 2019
5ZX2
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BU of 5zx2 by Molmil
Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ECF sigma factor sigma H and 7nt RNA
分子名称: DNA (47-MER), DNA (48-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Li, L, Zhang, Y.
登録日2018-05-17
公開日2019-03-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for transcription initiation by bacterial ECF sigma factors.
Nat Commun, 10, 2019
6KOO
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BU of 6koo by Molmil
Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 7 nt
分子名称: DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*TP*G)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Li, L, Zhang, Y.
登録日2019-08-12
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription.
Proc.Natl.Acad.Sci.USA, 117, 2020
8E95
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BU of 8e95 by Molmil
Mycobacterium tuberculosis RNAP elongation complex
分子名称: DNA (25-MER), DNA (33-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Delbeau, M, Darst, S.A, Campbell, E.A.
登録日2022-08-26
公開日2023-03-22
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
6JCX
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BU of 6jcx by Molmil
Mycobacterium tuberculosis transcription initiation complex with ECF sigma factor sigma H and 6nt RNA
分子名称: DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Li, L, Zhang, Y.
登録日2019-01-30
公開日2019-05-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.903 Å)
主引用文献Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
8E74
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BU of 8e74 by Molmil
Mycobacterium tuberculosis RNAP paused elongation complex with NusG transcription factor
分子名称: DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Delbeau, M, Darst, S.A, Campbell, E.A.
登録日2022-08-23
公開日2023-03-22
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
7KIF
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BU of 7kif by Molmil
Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 transcription factor
分子名称: DNA (55-MER), DNA (63-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Lilic, M, Darst, S.A, Campbell, E.A.
登録日2020-10-23
公開日2021-04-21
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7.
Mol.Cell, 81, 2021
8EHQ
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BU of 8ehq by Molmil
Mycobacterium tuberculosis paused transcription complex with Bacillus subtilis NusG
分子名称: DNA (38-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Vishwakarma, R.K, Murakami, K.S.
登録日2022-09-14
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase.
Proc.Natl.Acad.Sci.USA, 120, 2023
6KON
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BU of 6kon by Molmil
Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 5 nt
分子名称: DNA (5'-D(P*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*TP*G)-3'), DNA (5'-D(P*GP*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Li, L, Zhang, Y.
登録日2019-08-12
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription.
Proc.Natl.Acad.Sci.USA, 117, 2020
8E82
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BU of 8e82 by Molmil
Mycobacterium tuberculosis RNAP elongation complex with NusG transcription factor
分子名称: DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Delbeau, M, Darst, S.A, Campbell, E.A.
登録日2022-08-25
公開日2023-03-22
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
8EOS
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BU of 8eos by Molmil
M. tuberculosis RNAP elongation complex with NusG and CMPCPP
分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (36-MER), DNA (38-MER), ...
著者Vishwakarma, R.K, Murakami, K.S.
登録日2022-10-04
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase.
Proc.Natl.Acad.Sci.USA, 120, 2023
6JCY
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BU of 6jcy by Molmil
Mycobacterium tuberculosis RNA polymerase transcription initiation open complex with a chimeric ECF sigma factor sigH/E
分子名称: DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Li, L, Zhang, Y.
登録日2019-01-30
公開日2019-05-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.106 Å)
主引用文献Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
8E8M
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BU of 8e8m by Molmil
Mycobacterium tuberculosis RNAP paused elongation complex
分子名称: DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Delbeau, M, Darst, S.A, Campbell, E.A.
登録日2022-08-25
公開日2023-03-22
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
8EJ3
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BU of 8ej3 by Molmil
M. tuberculosis RNAP pause escaped complex with Bacillus subtilis NusG and GMPCPP
分子名称: DNA (29-MER), DNA (32-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Vishwakarma, R.K, Murakami, K.S.
登録日2022-09-16
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EOE
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BU of 8eoe by Molmil
Mycobacterium tuberculosis transcription elongation complex with Bacillus subtilis NusG (EC_LG)
分子名称: DNA (35-MER), DNA (38-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Vishwakarm, R.K, Murakami, K.S.
登録日2022-10-03
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EXY
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BU of 8exy by Molmil
M. tuberculosis RNAP paused complex with B. subtilis NusG and GMPCPP
分子名称: DNA (38-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Vishwakarma, R.K, Murakami, K.S.
登録日2022-10-26
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase.
Proc.Natl.Acad.Sci.USA, 120, 2023
6C04
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BU of 6c04 by Molmil
Mtb RNAP Holo/RbpA/double fork DNA -closed clamp
分子名称: DNA (26-MER), DNA (31-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M.
登録日2017-12-27
公開日2018-03-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018
8EOF
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BU of 8eof by Molmil
Mycobacterium tuberculosis transcription elongation complex with Bacillus subtilis NusG (EC_PG)
分子名称: DNA (35-MER), DNA (38-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Vishwakarm, R.K, Murakami, K.S.
登録日2022-10-03
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EOT
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BU of 8eot by Molmil
M. tuberculosis RNAP elongation complex with NusG
分子名称: DNA (31-MER), DNA (33-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Vishwakarma, R.K, Murakami, K.S.
登録日2022-10-04
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase.
Proc.Natl.Acad.Sci.USA, 120, 2023
6DVC
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BU of 6dvc by Molmil
Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 6nt spacer
分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Lin, W, Das, K, Feng, Y, Ebright, R.H.
登録日2018-06-23
公開日2019-02-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
6KOP
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BU of 6kop by Molmil
Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 9 nt
分子名称: DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*TP*G)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Li, L, Zhang, Y.
登録日2019-08-12
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.303 Å)
主引用文献RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription.
Proc.Natl.Acad.Sci.USA, 117, 2020
6KOQ
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BU of 6koq by Molmil
Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 10 nt
分子名称: DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*TP*G)-3'), DNA (5'-D(*TP*TP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Li, L, Zhang, Y.
登録日2019-08-12
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.353 Å)
主引用文献RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription.
Proc.Natl.Acad.Sci.USA, 117, 2020
6BZO
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BU of 6bzo by Molmil
Mtb RNAP Holo/RbpA/Fidaxomicin/upstream fork DNA
分子名称: DNA (26-MER), DNA (32-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J.
登録日2017-12-25
公開日2018-03-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018

 

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