5YVN
 
 | | Human Glutathione Transferase Omega1 | | 分子名称: | ACETATE ION, GLUTATHIONE, Glutathione S-transferase omega-1, ... | | 著者 | Saisawang, C, Ketterman, A, Wongsantichon, J. | | 登録日 | 2017-11-27 | | 公開日 | 2018-11-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | Glutathione transferase Omega 1-1 (GSTO1-1) modulates Akt and MEK1/2 signaling in human neuroblastoma cell SH-SY5Y.
Proteins, 87, 2019
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3VLN
 | | Human Glutathione Transferase O1-1 C32S Mutant in Complex with Ascorbic Acid | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, ASCORBIC ACID, ... | | 著者 | Brock, J, Board, P.G, Oakley, A.J. | | 登録日 | 2011-12-02 | | 公開日 | 2012-05-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural insights into the dehydroascorbate reductase activity of human omega-class glutathione transferases.
J.Mol.Biol., 420, 2012
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4IS0
 | | Structural Insights into Omega-Class Glutathione Transferases: A Snapshot of Enzyme Reduction and Identification of the Non-Catalytic Ligandin Site. | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Glutathione S-transferase omega-1, L-gamma-glutamyl-S-[2-(4-nitrophenyl)-2-oxoethyl]-L-cysteinylglycine, ... | | 著者 | Brock, J, Oakley, A.J. | | 登録日 | 2013-01-15 | | 公開日 | 2013-04-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.721 Å) | | 主引用文献 | Structural insights into omega-class glutathione transferases: a snapshot of enzyme reduction and identification of a non-catalytic ligandin site.
Plos One, 8, 2013
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5YVO
 | | Human Glutathione Transferase Omega1 covalently bound to ML175 inhibitor | | 分子名称: | ACETATE ION, Glutathione S-transferase omega-1, N-{3-[(2-chloro-acetyl)-(4-nitro-phenyl)-amino]-propyl}-2,2,2-trifluoro-acetamide, ... | | 著者 | Saisawang, C, Ketterman, A, Wongsantichon, J. | | 登録日 | 2017-11-27 | | 公開日 | 2018-11-28 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Glutathione transferase Omega 1-1 (GSTO1-1) modulates Akt and MEK1/2 signaling in human neuroblastoma cell SH-SY5Y.
Proteins, 87, 2019
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6PNM
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6PNO
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4YQU
 | | Glutathione S-transferase Omega 1 bound to covalent inhibitor C1-31 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Glutathione S-transferase omega-1, N-{5-(azepan-1-ylsulfonyl)-2-[(ethylsulfanyl)methoxy]phenyl}acetamide | | 著者 | Stuckey, J.A. | | 登録日 | 2015-03-13 | | 公開日 | 2016-10-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor.
Nat Commun, 7, 2016
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1EEM
 | | GLUTATHIONE TRANSFERASE FROM HOMO SAPIENS | | 分子名称: | GLUTATHIONE, GLUTATHIONE-S-TRANSFERASE, SULFATE ION | | 著者 | Board, P, Coggan, M, Chelvanayagam, G, Easteal, S, Jermiin, L.S, Schulte, G.K, Danley, D.E, Hoth, L.R, Griffor, M.C, Kamath, A.V, Rosner, M.H, Chrunyk, B.A, Perregaux, D.E, Gabel, C.A, Geoghegan, K.F, Pandit, J. | | 登録日 | 2000-02-01 | | 公開日 | 2000-08-11 | | 最終更新日 | 2018-04-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Identification, characterization, and crystal structure of the Omega class glutathione transferases.
J.Biol.Chem., 275, 2000
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5UEH
 | | Structure of GSTO1 covalently conjugated to quinolinic acid fluorosulfate | | 分子名称: | 2-(4-chlorophenyl)-6-[(fluorosulfonyl)oxy]quinoline-4-carboxylic acid, GLYCEROL, Glutathione S-transferase omega-1, ... | | 著者 | Mortenson, D.E, Wilson, I.A, Kelly, J.W. | | 登録日 | 2017-01-02 | | 公開日 | 2018-01-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | "Inverse Drug Discovery" Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates.
J. Am. Chem. Soc., 140, 2018
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6MHC
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4YQV
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6PNN
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3LFL
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6MHD
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5V3Q
 | | Human GSTO1-1 complexed with ML175 | | 分子名称: | Glutathione S-transferase omega-1, N-{3-[(2-chloro-acetyl)-(4-nitro-phenyl)-amino]-propyl}-2,2,2-trifluoro-acetamide, SULFATE ION | | 著者 | Oakley, A.J. | | 登録日 | 2017-03-07 | | 公開日 | 2017-12-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity.
Sci Rep, 7, 2017
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4YQM
 | | Glutathione S-transferase Omega 1 bound to covalent inhibitor C1-27 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloro-N-[4-chloro-3-(dimethylsulfamoyl)phenyl]acetamide, Glutathione S-transferase omega-1 | | 著者 | Stuckey, J.A. | | 登録日 | 2015-03-13 | | 公開日 | 2016-10-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor.
Nat Commun, 7, 2016
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6MHB
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