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PDB: 12 件

1SZD
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Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, CHLORIDE ION, GLYCEROL, ...
著者Zhao, K, Harshaw, R, Chai, X, Marmorstein, R.
登録日2004-04-05
公開日2004-06-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1Q1A
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Structure of the yeast Hst2 protein deacetylase in ternary complex with 2'-O-acetyl ADP ribose and histone peptide
分子名称: 2'-O-ACETYL ADENOSINE-5-DIPHOSPHORIBOSE, HST2 protein, Histone H4, ...
著者Zhao, K, Chai, X, Marmorstein, R.
登録日2003-07-18
公開日2003-11-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of the yeast Hst2 protein deacetylase in ternary complex with 2'-O-Acetyl ADP ribose and histone peptide.
Structure, 11, 2003
1SZC
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Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases
分子名称: CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, CHLORIDE ION, GLYCEROL, ...
著者Zhao, K, Harshaw, R, Chai, X, Marmorstein, R.
登録日2004-04-05
公開日2004-06-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases.
Proc.Natl.Acad.Sci.Usa, 101, 2004
7F4E
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Crystal structure of Hst2 in complex with H3K9bz peptide
分子名称: Histone H3, NAD-dependent protein deacetylase HST2, ZINC ION
著者Wang, D, Yan, F, Chen, Y.
登録日2021-06-18
公開日2022-03-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Global profiling of regulatory elements in the histone benzoylation pathway.
Nat Commun, 13, 2022
7F51
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Crystal structure of Hst2 in complex with 2'-O-Benzoyl ADP Ribose
分子名称: NAD-dependent protein deacetylase HST2, ZINC ION, [(2R,3R,4R,5R)-5-[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-2,4-bis(oxidanyl)oxolan-3-yl] benzoate
著者Wang, D, Yan, F, Chen, Y.
登録日2021-06-21
公開日2022-03-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Global profiling of regulatory elements in the histone benzoylation pathway.
Nat Commun, 13, 2022
2OD2
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Crystal Structure of yHst2 I117F mutant bound to carba-NAD+ and an acetylated H4 peptide
分子名称: Acetylated H4 peptide, CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, GLYCEROL, ...
著者Sanders, B.D.
登録日2006-12-21
公開日2007-02-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes.
Mol.Cell, 25, 2007
2OD7
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Crystal Structure of yHst2 bound to the intermediate analogue ADP-HPD, and and aceylated H4 peptide
分子名称: 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, Acetylated histone H4 peptide, NAD-dependent deacetylase HST2, ...
著者Marmorstein, R.Q, Sanders, B.D.
登録日2006-12-21
公開日2007-02-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes.
Mol.Cell, 25, 2007
2QQF
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Hst2 bound to ADP-HPD and Acetylated histone H4
分子名称: 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, Histone H4, NAD-dependent deacetylase HST2, ...
著者Marmorstein, R, Sanders, B.D, Zhao, K, Slama, J.
登録日2007-07-26
公開日2007-10-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes.
Mol.Cell, 25, 2007
2OD9
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Structural Basis for Nicotinamide Inhibition and Base Exchange in Sir2 Enzymes
分子名称: 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, H4 peptide, NAD-dependent deacetylase HST2, ...
著者Marmorstein, R, Sanders, B.D.
登録日2006-12-21
公開日2007-02-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes.
Mol.Cell, 25, 2007
2QQG
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Hst2 bound to ADP-HPD, acetyllated histone H4 and nicotinamide
分子名称: 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, Histone H4, NAD-dependent deacetylase HST2, ...
著者Marmorstein, R, Sanders, B, Zhao, K, Slama, J.
登録日2007-07-26
公開日2007-10-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes.
Mol.Cell, 25, 2007
1Q14
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BU of 1q14 by Molmil
Structure and autoregulation of the yeast Hst2 homolog of Sir2
分子名称: CHLORIDE ION, HST2 protein, ZINC ION
著者Zhao, K, Chai, X, Clements, A, Marmorstein, R.
登録日2003-07-18
公開日2003-09-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and autoregulation of the Yeast Hst2 homolog of Sir2
Nat.Struct.Biol., 10, 2003
1Q17
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Structure of the yeast Hst2 protein deacetylase in ternary complex with 2'-O-acetyl ADP ribose and histone peptide
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, CHLORIDE ION, HST2 protein, ...
著者Zhao, K, Chai, X, Marmorstein, R.
登録日2003-07-18
公開日2003-11-18
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the Yeast Hst2 Protein Deacetylase in Ternary Complex with 2'-O-Acetyl ADP Ribose and Histone Peptide.
Structure, 11, 2003

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件を2024-08-07に公開中

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