3B7Y
| Crystal structure of the C2 Domain of the E3 Ubiquitin-Protein Ligase NEDD4 | 分子名称: | CALCIUM ION, E3 ubiquitin-protein ligase NEDD4 | 著者 | Walker, J.R, Ruzanov, M, Butler-Cole, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2007-10-31 | 公開日 | 2007-11-27 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | C2 Domain of the Human E3 Ubiquitin-Protein Ligase NEDD4. To be Published
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5AHT
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2XBF
| Nedd4 HECT structure | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE NEDD4 | 著者 | Maspero, E, Cecatiello, V, Musacchio, A, Polo, S, Pasqualato, S. | 登録日 | 2010-04-09 | 公開日 | 2011-03-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | 主引用文献 | Structure of the Hect:Ubiquitin Complex and its Role in Ubiquitin Chain Elongation Embo Rep., 12, 2011
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5C7J
| CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT | 分子名称: | E3 ubiquitin-protein ligase NEDD4, Polyubiquitin-C | 著者 | Walker, J.R, Hu, J, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | 登録日 | 2015-06-24 | 公開日 | 2016-03-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016
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5C91
| NEDD4 HECT with covalently bound indole-based inhibitor | 分子名称: | E3 ubiquitin-protein ligase NEDD4, methyl (2E)-4-{[(5-methoxy-1,2-dimethyl-1H-indol-3-yl)carbonyl]amino}but-2-enoate | 著者 | Span, I, Smith, A.T, Kathman, S, Statsyuk, A.V, Rosenzweig, A.C. | 登録日 | 2015-06-26 | 公開日 | 2015-09-30 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | A Small Molecule That Switches a Ubiquitin Ligase From a Processive to a Distributive Enzymatic Mechanism. J. Am. Chem. Soc., 137, 2015
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4BBN
| NEDD4 HECT-Ub:Ub complex | 分子名称: | E3 UBIQUITIN-PROTEIN LIGASE NEDD4, POLYUBIQUITIN-B | 著者 | Maspero, E, Valentini, E, Mari, S, Cecatiello, V, Polo, S, Pasqualato, S. | 登録日 | 2012-09-27 | 公開日 | 2013-05-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Structure of a Ubiquitin-Loaded Hect Ligase Reveals the Molecular Basis for Catalytic Priming Nat.Struct.Mol.Biol., 20, 2013
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4N7F
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4BE8
| NEDD4 HECT A889F structure | 分子名称: | E3 UBIQUITIN-PROTEIN LIGASE NEDD4 | 著者 | Maspero, E, Valentini, E, Mari, S, Cecatiello, V, Polo, S, Pasqualato, S. | 登録日 | 2013-03-06 | 公開日 | 2013-05-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.996 Å) | 主引用文献 | Structure of a Ubiquitin-Loaded Hect Ligase Reveals the Molecular Basis for Catalytic Priming Nat.Struct.Mol.Biol., 20, 2013
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4N7H
| Crystal Structure of the Complex of 3rd WW domain of Human Nedd4 and 1st PPXY Motif of ARRDC3 | 分子名称: | Arrestin domain-containing protein 3, E3 ubiquitin-protein ligase NEDD4, GUANIDINE | 著者 | Qi, S, O'Hayre, M, Gutkind, J.S, Hurley, J. | 登録日 | 2013-10-15 | 公開日 | 2014-01-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3). J.Biol.Chem., 289, 2014
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2XBB
| Nedd4 HECT:Ub complex | 分子名称: | E3 UBIQUITIN-PROTEIN LIGASE NEDD4, GLYCEROL, UBIQUITIN | 著者 | Maspero, E, Cecatiello, V, Musacchio, A, Polo, S, Pasqualato, S. | 登録日 | 2010-04-08 | 公開日 | 2011-03-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Structure of the Hect:Ubiquitin Complex and its Role in Ubiquitin Chain Elongation Embo Rep., 12, 2011
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2KQ0
| Human NEDD4 3rd WW Domain Complex with Ebola Zaire Virus Matrix Protein VP40 Derived Peptide ILPTAPPEYMEA | 分子名称: | 12-mer from Matrix protein VP40, E3 ubiquitin-protein ligase NEDD4 | 著者 | Iglesias-Bexiga, M, Macias, M, Bonet, R, Blanco, F.J, Cobos, E.S, Luque, I. | 登録日 | 2009-10-23 | 公開日 | 2010-11-03 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Human NEDD4 3rd WW Domain Complex with Ebola Zaire Virus Matrix Protein VP40 Derived Peptide To be Published
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2M3O
| Structure and dynamics of a human Nedd4 WW domain-ENaC complex | 分子名称: | Amiloride-sensitive sodium channel subunit alpha, E3 ubiquitin-protein ligase NEDD4 | 著者 | Bobby, R, Medini, K, Neudecker, P, Lee, V, MacDonald, F.J, Brimble, M.A, Lott, J, Dingley, A.J. | 登録日 | 2013-01-23 | 公開日 | 2013-08-28 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and dynamics of human Nedd4-1 WW3 in complex with the alpha ENaC PY motif. Biochim.Biophys.Acta, 1834, 2013
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2KPZ
| Human NEDD4 3RD WW Domain Complex with The Human T-cell Leukemia virus 1 GAG-Pro poliprotein Derived Peptide SDPQIPPPYVEP | 分子名称: | 12-mer from Gag-Pro polyprotein, E3 ubiquitin-protein ligase NEDD4 | 著者 | Iglesias-Bexiga, M, Macias, M, Bonet, R, Blanco, F.J, Cobos, E.S, Luque, I. | 登録日 | 2009-10-23 | 公開日 | 2010-11-03 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Human NEDD4 3RD WW Domain Complex with Human T-cell Leukemia virus GAP-Pro Poliprotein Derived Peptide To be Published
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