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PDB: 8 件

1BF5
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TYROSINE PHOSPHORYLATED STAT-1/DNA COMPLEX
分子名称: DNA (5'-D(*AP*CP*AP*GP*TP*TP*TP*CP*CP*CP*GP*TP*AP*AP*AP*TP*G P*C)-3'), DNA (5'-D(*TP*GP*CP*AP*TP*TP*TP*AP*CP*GP*GP*GP*AP*AP*AP*CP*T P*G)-3'), SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA/BETA
著者Kuriyan, J, Zhao, Y, Chen, X, Vinkemeier, U, Jeruzalmi, D, Darnell Jr, J.E.
登録日1998-05-27
公開日1998-08-12
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA.
Cell(Cambridge,Mass.), 93, 1998
1YVL
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Structure of Unphosphorylated STAT1
分子名称: 5-residue peptide, GOLD ION, Signal transducer and activator of transcription 1-alpha/beta
著者Mao, X, Ren, Z, Parker, G.N, Sondermann, H, Pastorello, M.A, Wang, W, McMurray, J.S, Demeler, B, Darnell Jr, J.E, Chen, X.
登録日2005-02-16
公開日2005-03-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural bases of unphosphorylated STAT1 association and receptor binding.
Mol.Cell, 17, 2005
8YYU
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A tetrameric STAT1-DNA complex
分子名称: DNA (5'-D(P*AP*CP*AP*GP*TP*TP*TP*CP*CP*CP*GP*TP*AP*AP*AP*TP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*TP*TP*TP*AP*CP*GP*GP*GP*AP*AP*AP*CP*TP*G)-3'), Signal transducer and activator of transcription 1-alpha/beta
著者Sugiyama, A, Minami, M, Sugita, Y, Ose, T.
登録日2024-04-04
公開日2025-03-26
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Structural analysis reveals how tetrameric tyrosine-phosphorylated STAT1 is targeted by the rabies virus P-protein.
Sci.Signal., 18, 2025
8YYV
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A dimeric STAT1-DNA complex
分子名称: DNA (5'-D(P*AP*CP*AP*GP*TP*TP*TP*CP*CP*CP*GP*TP*AP*AP*AP*TP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*TP*TP*TP*AP*CP*GP*GP*GP*AP*AP*AP*CP*TP*G)-3'), Signal transducer and activator of transcription 1-alpha/beta
著者Sugiyama, A, Minami, M, Sugita, Y, Ose, T.
登録日2024-04-04
公開日2025-03-26
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Structural analysis reveals how tetrameric tyrosine-phosphorylated STAT1 is targeted by the rabies virus P-protein.
Sci.Signal., 18, 2025
7NUF
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BU of 7nuf by Molmil
Vaccinia virus protein 018 in complex with STAT1
分子名称: ACETYL GROUP, SULFATE ION, Signal transducer and activator of transcription 1-alpha/beta, ...
著者Pantelejevs, T, Talbot-Cooper, C, Smith, G.L, Hyvonen, M.
登録日2021-03-12
公開日2021-07-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.0004015 Å)
主引用文献Poxviruses and paramyxoviruses use a conserved mechanism of STAT1 antagonism to inhibit interferon signaling.
Cell Host Microbe, 30, 2022
3WWT
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Crystal Structure of the Y3:STAT1ND complex
分子名称: C' protein, CALCIUM ION, Signal transducer and activator of transcription 1-alpha/beta
著者Oda, K, Sakaguchi, T, Matoba, Y.
登録日2014-06-27
公開日2015-07-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis of the Inhibition of STAT1 Activity by Sendai Virus C Protein.
J.Virol., 89, 2015
8D3F
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Crystal structure of human STAT1 in complex with the repeat region from Toxoplasma protein TgIST
分子名称: Signal transducer and activator of transcription 1-alpha/beta,Inhibitor of STAT1-dependent transcription TgIST
著者Huang, Z, Liu, H, Nix, J.C, Amarasinghe, G.K, Sibley, L.D.
登録日2022-06-01
公開日2022-07-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献The intrinsically disordered protein TgIST from Toxoplasma gondii inhibits STAT1 signaling by blocking cofactor recruitment.
Nat Commun, 13, 2022
2KA6
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NMR structure of the CBP-TAZ2/STAT1-TAD complex
分子名称: CREB-binding protein, Signal transducer and activator of transcription 1-alpha/beta, ZINC ION
著者Wojciak, J.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
登録日2008-10-30
公開日2009-04-07
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains.
Embo J., 28, 2009

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件を2025-04-30に公開中

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