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PDB: 19 件

4O5L
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Crystal structure of broadly neutralizing antibody F045-092
分子名称: Fab F045-092 heavy chain, Fab F045-092 light chain, PHOSPHATE ION
著者Lee, P.S, Wilson, I.A.
登録日2013-12-19
公開日2014-04-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5045 Å)
主引用文献Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014
6UC5
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Fab397 in complex with NPNA peptide
分子名称: Fab397 heavy chain, Fab397 light chain, NPNA peptide
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2019-09-13
公開日2020-01-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Diverse Antibody Responses to Conserved Structural Motifs in Plasmodium falciparum Circumsporozoite Protein.
J.Mol.Biol., 432, 2020
6UGS
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BU of 6ugs by Molmil
Crystal structure of the Fab fragment of PF06438179/GP1111 an infliximab biosimilar in a C-centered orthorhombic crystal form, Lot A
分子名称: Infliximab (Remicade) Fab Heavy Chain, Infliximab (Remicade) Fab Light Chain
著者Lerch, T.F, Sharpe, P, Mayclin, S.J, Edwards, T.E, Polleck, S, Rouse, J.C, Conlan, H.
登録日2019-09-26
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar.
BioDrugs, 34, 2020
6MGP
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Structure of human 4-1BB / 4-1BBL complex
分子名称: ACETATE ION, GLYCEROL, Tumor necrosis factor ligand superfamily member 9, ...
著者Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y.
登録日2018-09-14
公開日2018-11-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab
Nat Commun, 9, 2018
6UGT
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Crystal structure of the Fab fragment of PF06438179/GP1111 an infliximab biosimilar in a I-centered orthorhombic crystal form, Lot A
分子名称: 1,2-ETHANEDIOL, PF06438179 Fab Heavy Chain, PF06438179 Fab Light Chain
著者Lerch, T.F, Sharpe, P, Mayclin, S.J, Edwards, T.E, Polleck, S, Rouse, J.C, Conlan, H.D.
登録日2019-09-26
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar.
BioDrugs, 34, 2020
6UGU
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Crystal structure of the Fab fragment of anti-TNFa antibody infliximab (Remicade) in a C-centered orthorhombic crystal form, Lot C
分子名称: PF06438179 Fab Heavy Chain, PF06438179 Fab Light Chain
著者Lerch, T.F, Sharpe, P, Mayclin, S.J, Edwards, T.E, Polleck, S, Rouse, J.C, Conlan, H.D.
登録日2019-09-26
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar.
BioDrugs, 34, 2020
2X29
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Crystal structure of human4-1BB ligand ectodomain
分子名称: TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 9
著者Won, E.Y, Cho, H.S.
登録日2010-01-12
公開日2010-03-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Structure of the Trimer of Human 4-1Bb Ligand is Unique Among Members of the Tumor Necrosis Factor Superfamily.
J.Biol.Chem., 285, 2010
6BWV
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Crystal Structure of the 4-1BB/4-1BBL Complex
分子名称: DI(HYDROXYETHYL)ETHER, Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9
著者Oganesyan, V, Gilbreth, R.N, Baca, M.
登録日2017-12-15
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the human 4-1BB/4-1BBL complex.
J. Biol. Chem., 293, 2018
6UGV
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Crystal structure of the Fab fragment of anti-TNFa antibody infliximab (Remicade) in a I-centered orthorhombic crystal form, Lot C
分子名称: 1,2-ETHANEDIOL, Infliximab Fab Heavy Chain, Infliximab Fab Light Chain, ...
著者Lerch, T.F, Sharpe, P, Mayclin, S.J, Edwards, T.E, Polleck, S, Rouse, J.C, Conlan, H.D.
登録日2019-09-26
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar.
BioDrugs, 34, 2020
3CFJ
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Crystal structure of catalytic elimination antibody 34E4, orthorhombic crystal form
分子名称: CATALYTIC ANTIBODY FAB 34E4 HEAVY CHAIN fusion, CATALYTIC ANTIBODY FAB 34E4 LIGHT CHAIN fusion, GLYCEROL, ...
著者Debler, E.W, Wilson, I.A.
登録日2008-03-04
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Conformational isomerism can limit antibody catalysis.
J.Biol.Chem., 283, 2008
3CFK
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Crystal structure of catalytic elimination antibody 34E4, triclinic crystal form
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, CATALYTIC ANTIBODY FAB 34E4 HEAVY CHAIN,Uncharacterized protein, ...
著者Debler, E.W, Wilson, I.A.
登録日2008-03-04
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Conformational isomerism can limit antibody catalysis.
J.Biol.Chem., 283, 2008
6FIB
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BU of 6fib by Molmil
Structure of human 4-1BB ligand
分子名称: Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor ligand superfamily member 9,4-1BBL -CH/CL fusion, Tumor necrosis factor ligand superfamily member 9,Uncharacterized protein
著者Joseph, C, Claus, C, Ferrara, C, von Hirschheydt, T, Prince, C, Funk, D, Klein, C, Benz, J.
登録日2018-01-17
公開日2019-03-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy.
Sci Transl Med, 11, 2019
6CPR
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BU of 6cpr by Molmil
Crystal structure of 4-1BBL/4-1BB complex in C2 space group
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
著者Aruna, B, Zajonc, D.M.
登録日2018-03-14
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier.
J. Biol. Chem., 293, 2018
6D3N
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BU of 6d3n by Molmil
Crystal structure of h4-1BB ligand
分子名称: GLYCEROL, Tumor necrosis factor ligand superfamily member 9
著者Aruna, B, Zajonc, D.M, Doukov, T.
登録日2018-04-16
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier.
J. Biol. Chem., 293, 2018
6MGE
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BU of 6mge by Molmil
Structure of human 4-1BBL
分子名称: GLYCEROL, PHOSPHATE ION, Tumor necrosis factor ligand superfamily member 9
著者Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y.
登録日2018-09-13
公開日2018-11-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab.
Nat Commun, 9, 2018
6NZ7
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BU of 6nz7 by Molmil
Crystal structure of broadly neutralizing Influenza A antibody 429 B01 in complex with Hemagglutinin Hong Kong 1968
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 429 B01 FAB heavy chain, 429 B01 FAB light chain, ...
著者Zhou, T, Kwong, P.D.
登録日2019-02-13
公開日2019-05-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine.
Sci Immunol, 4, 2019
6AL5
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COMPLEX BETWEEN CD19 (N138Q MUTANT) AND B43 FAB
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, B-lymphocyte antigen CD19, B43 HEAVY CHAIN, ...
著者Teplyakov, A, Obmolova, G, Gilliland, G.L.
登録日2017-08-07
公開日2018-03-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of B-cell co-receptor CD19 in complex with antibody B43 reveals an unexpected fold.
Proteins, 86, 2018
6CU0
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BU of 6cu0 by Molmil
Crystal structure of 4-1BBL/4-1BB (C121S) complex in P21 space group
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9
著者Aruna, B, Zajonc, D.M, Doukov, T.
登録日2018-03-23
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier.
J. Biol. Chem., 293, 2018
6A3V
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BU of 6a3v by Molmil
Complex structure of human 4-1BB and 4-1BBL
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9
著者Li, Y, Zhang, C, Chai, Y, Qi, J, Tien, P, Gao, S, Gao, G.F.
登録日2018-06-17
公開日2018-10-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.391 Å)
主引用文献Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab.
Cell Rep, 25, 2018

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件を2024-09-04に公開中

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