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PDB: 26 件
4F29
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BU of 4f29 by Molmil
Quisqualate bound to the ligand binding domain of GluA3i
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Oswald, R.E.
登録日2012-05-07
公開日2012-05-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.749 Å)
主引用文献The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation.
Biochemistry, 51, 2012
3LSW
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BU of 3lsw by Molmil
Aniracetam bound to the ligand binding domain of GluA3
分子名称: 1-(4-METHOXYBENZOYL)-2-PYRROLIDINONE, GLUTAMIC ACID, GluA2 S1S2 domain, ...
著者Ahmed, A.H, Oswald, R.E.
登録日2010-02-13
公開日2010-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.752 Å)
主引用文献Piracetam Defines a New Binding Site for Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors.
J.Med.Chem., 53, 2010
4F1Y
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BU of 4f1y by Molmil
CNQX bound to the ligand binding domain of GluA3
分子名称: 7-nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Oswald, R.E.
登録日2012-05-07
公開日2012-05-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation.
Biochemistry, 51, 2012
3M3K
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BU of 3m3k by Molmil
Ligand binding domain (S1S2) of GluA3 (flop)
分子名称: GLUTAMIC ACID, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Ptak, C.P, Oswald, R.E.
登録日2010-03-09
公開日2010-03-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.793 Å)
主引用文献Molecular mechanism of flop selectivity and subsite recognition for an AMPA receptor allosteric modulator: structures of GluA2 and GluA3 in complexes with PEPA.
Biochemistry, 49, 2010
4F3B
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BU of 4f3b by Molmil
Glutamate bound to the D655A mutant of the ligand binding domain of GluA3
分子名称: GLUTAMIC ACID, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Oswald, R.E.
登録日2012-05-09
公開日2012-05-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.818 Å)
主引用文献The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation.
Biochemistry, 51, 2012
4F39
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BU of 4f39 by Molmil
Kainate bound to the ligand binding domain of GluA3
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Oswald, R.E.
登録日2012-05-09
公開日2012-05-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.834 Å)
主引用文献The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation.
Biochemistry, 51, 2012
3DLN
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BU of 3dln by Molmil
Crystal structure of the binding domain of the AMPA subunit GluR3 bound to glutamate
分子名称: GLUTAMIC ACID, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Wang, Q, Sondermann, H, Oswald, R.E.
登録日2008-06-27
公開日2008-11-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structure of the S1S2 glutamate binding domain of GLuR3.
Proteins, 75, 2008
4F2O
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BU of 4f2o by Molmil
Quisqualate bound to the D655A mutant of the ligand binding domain of GluA3
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Oswald, R.E.
登録日2012-05-08
公開日2012-05-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.912 Å)
主引用文献The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation.
Biochemistry, 51, 2012
6FPJ
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BU of 6fpj by Molmil
Structure of the AMPAR GluA3 N-terminal domain bound to phosphate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Herguedas, B, Garcia-Nafria, J, Greger, I.
登録日2018-02-09
公開日2018-12-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Druggability Simulations and X-Ray Crystallography Reveal a Ligand-Binding Site in the GluA3 AMPA Receptor N-Terminal Domain.
Structure, 27, 2019
3LSX
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BU of 3lsx by Molmil
Piracetam bound to the ligand binding domain of GluA3
分子名称: 2-(2-oxopyrrolidin-1-yl)acetamide, GLUTAMIC ACID, GluA3 S1S2 domain, ...
著者Ahmed, A.H, Oswald, R.E.
登録日2010-02-13
公開日2011-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献Piracetam Defines a New Binding Site for Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors.
J.Med.Chem., 53, 2010
4F22
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BU of 4f22 by Molmil
Kainate bound to the K660A mutant of the ligand binding domain of GluA3
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Oswald, R.E.
登録日2012-05-07
公開日2012-05-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation.
Biochemistry, 51, 2012
4F3G
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BU of 4f3g by Molmil
Kainate bound to the ligand binding domain of GluA3i
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Oswald, R.E.
登録日2012-05-09
公開日2012-05-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.064 Å)
主引用文献The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation.
Biochemistry, 51, 2012
3DP4
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BU of 3dp4 by Molmil
Crystal structure of the binding domain of the AMPA subunit GluR3 bound to AMPA
分子名称: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Wang, Q, Sondermann, H, Oswald, R.E.
登録日2008-07-07
公開日2008-11-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structure of the S1S2 glutamate binding domain of GLuR3.
Proteins, 75, 2008
5FWY
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BU of 5fwy by Molmil
Crystal structure of the AMPA receptor GluA2/A3 N-terminal domain heterodimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMATE RECEPTOR 2, GLUTAMATE RECEPTOR 3, ...
著者Herguedas, B, Garcia-Nafria, J, Greger, I.H.
登録日2016-02-21
公開日2016-03-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structure and Organization of Heteromeric Ampa-Type Glutamate Receptors.
Science, 352, 2016
3O21
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BU of 3o21 by Molmil
High resolution structure of GluA3 N-terminal domain (NTD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 3, PHOSPHATE ION
著者Rossmann, M, Sukumaran, M, Penn, A.C, Veprintsev, D.B, Babu, M.M, Jensen, M.H, Greger, I.H.
登録日2010-07-22
公開日2011-03-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Dynamics and allosteric potential of the AMPA receptor N-terminal domain
Embo J., 30, 2011
4F2Q
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BU of 4f2q by Molmil
Quisqualate bound to the D655A mutant of the ligand binding domain of GluA3
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Oswald, R.E.
登録日2012-05-08
公開日2012-05-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.202 Å)
主引用文献The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation.
Biochemistry, 51, 2012
4F31
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BU of 4f31 by Molmil
Kainate bound to the D655A mutant of the ligand binding domain of GluA3
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Oswald, R.E.
登録日2012-05-08
公開日2012-05-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.286 Å)
主引用文献The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation.
Biochemistry, 51, 2012
3RT8
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BU of 3rt8 by Molmil
Chlorowillardiine bound to the ligand binding domain of GluA3
分子名称: 3-(5-chloro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-L-alanine, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Oswald, R.E.
登録日2011-05-03
公開日2011-05-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.426 Å)
主引用文献Mechanisms of Modal Activation of GluA3 Receptors.
Mol.Pharmacol., 80, 2011
3M3F
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BU of 3m3f by Molmil
PEPA bound to the ligand binding domain of GluA3 (flop form)
分子名称: 2-[2,6-difluoro-4-({2-[(phenylsulfonyl)amino]ethyl}sulfanyl)phenoxy]acetamide, GLUTAMIC ACID, Glutamate receptor 3, ...
著者Ahmed, A.H, Ptak, C.P, Oswald, R.E.
登録日2010-03-09
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular mechanism of flop selectivity and subsite recognition for an AMPA receptor allosteric modulator: structures of GluA2 and GluA3 in complexes with PEPA.
Biochemistry, 49, 2010
6FLR
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BU of 6flr by Molmil
Super-open structure of the AMPAR GluA3 N-terminal domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 3
著者Garcia-Nafria, J.
登録日2018-01-27
公開日2018-12-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Druggability Simulations and X-Ray Crystallography Reveal a Ligand-Binding Site in the GluA3 AMPA Receptor N-Terminal Domain.
Structure, 27, 2019
3RT6
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BU of 3rt6 by Molmil
Fluorowillardiine bound to the ligand binding domain of GluA3
分子名称: 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 3, ZINC ION
著者Ahmed, A.H, Oswald, R.E.
登録日2011-05-03
公開日2011-05-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.836 Å)
主引用文献Mechanisms of Modal Activation of GluA3 Receptors.
Mol.Pharmacol., 80, 2011
3P3W
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BU of 3p3w by Molmil
Structure of a dimeric GluA3 N-terminal domain (NTD) at 4.2 A resolution
分子名称: Glutamate receptor 3
著者Rossmann, M, Sukumaran, M, Greger, I.H.
登録日2010-10-05
公開日2011-03-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Dynamics and allosteric potential of the AMPA receptor N-terminal domain
Embo J., 30, 2011
6NJM
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BU of 6njm by Molmil
Architecture and subunit arrangement of native AMPA receptors
分子名称: 15F1 Fab heavy chain, 15F1 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gouaux, E, Zhao, Y.
登録日2019-01-03
公開日2019-04-24
最終更新日2021-05-05
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM.
Science, 364, 2019
6NJN
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BU of 6njn by Molmil
Architecture and subunit arrangement of native AMPA receptors
分子名称: 11B8 scFv, 15F1 Fab heavy chain, 15F1 Fab light chain, ...
著者Gouaux, E, Zhao, Y.
登録日2019-01-03
公開日2019-04-24
最終更新日2021-05-05
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM.
Science, 364, 2019
5IDE
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BU of 5ide by Molmil
Cryo-EM structure of GluA2/3 AMPA receptor heterotetramer (model I)
分子名称: Glutamate receptor 2, Glutamate receptor 3
著者Herguedas, B, Garcia-Nafria, J, Fernandez-Leiro, R, Greger, I.H.
登録日2016-02-24
公開日2016-03-16
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (8.25 Å)
主引用文献Structure and organization of heteromeric AMPA-type glutamate receptors.
Science, 352, 2016

 

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