4F1Y

CNQX bound to the ligand binding domain of GluA3

Summary for 4F1Y

• Entry DOI: 10.2210/pdb4f1y/pdb
• Related: 4F22 4F29 4F2O 4F2Q 4F31
• Descriptor: Glutamate receptor 3, 7-nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile, ZINC ION, ... (4 entities in total)
• Functional Keywords: glutamate receptor, glua3, glur3, ampa receptor, s1s2, lbd, neurotransmitter receptor, cnqx, transport protein, transport protein-agonist complex, transport protein/agonist
• Biological source: Rattus norvegicus (rat); More
• Cellular location: Cell membrane ; Multi-pass membrane protein : P19492
• Total number of polymer chains: 2
• Total formula weight: 58531.90

Authors

Ahmed, A.H.,Oswald, R.E. (deposition date: 2012-05-07, release date: 2012-05-16, Last modification date: 2023-09-13)

• Primary citation: Holley, S.M.,Ahmed, A.H.,Srinivasan, J.,Murthy, S.E.,Weiland, G.A.,Oswald, R.E.,Nowak, L.M.; The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation.; Biochemistry, 51:4015-4027, 2012; PubMed: 22512472; DOI: 10.1021/bi3001837

Experimental method

X-RAY DIFFRACTION (1.79 Å)