4F1Y

CNQX bound to the ligand binding domain of GluA3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015276	molecular_function	ligand-gated monoatomic ion channel activity
A	0016020	cellular_component	membrane
C	0015276	molecular_function	ligand-gated monoatomic ion channel activity
C	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CNI A 401

Chain	Residue
A	GLU13
A	TYR220
A	HOH574
A	HOH730
A	TYR61
A	PRO89
A	LEU90
A	THR91
A	ARG96
A	THR174
A	GLU193
A	MET196

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 402

Chain	Residue
A	HIS23
A	HOH729
C	HIS23

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 403

Chain	Residue
A	GLU42
A	LYS45
A	HIS46
A	LEU246

---

site_id	AC4
Number of Residues	14
Details	BINDING SITE FOR RESIDUE CNI C 401

Chain	Residue
C	GLU13
C	TYR61
C	PRO89
C	LEU90
C	THR91
C	ARG96
C	THR174
C	GLU193
C	MET196
C	TYR220
C	HOH537
C	HOH539
C	HOH669
C	HOH746

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:19003990, ECO:0000269|PubMed:20199107, ECO:0007744|PDB:3DLN, ECO:0007744|PDB:3M3F, ECO:0007744|PDB:3M3K

Chain	Residue	Details
A	PRO89
C	SER142
C	THR143
C	GLU193
A	THR91
A	ARG96
A	SER142
A	THR143
A	GLU193
C	PRO89
C	THR91
C	ARG96

---