4F31

Kainate bound to the D655A mutant of the ligand binding domain of GluA3

Summary for 4F31

Entry DOI	10.2210/pdb4f31/pdb
Related	4F1Y 4F22 4F29 4F2O 4F2Q 4F39 4F3B 4F3G
Descriptor	Glutamate receptor 3, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, ZINC ION, ... (4 entities in total)
Functional Keywords	glutamate receptor, glua3, glur3, ampa receptor, s1s2, lbd, neurotransmitter receptor, kainate, transport protein-agonist complex, transport protein/agonist
Biological source	Rattus norvegicus (rat) More
Cellular location	Cell membrane ; Multi-pass membrane protein : P19492
Total number of polymer chains	2
Total formula weight	58540.88
Authors	Ahmed, A.H.,Oswald, R.E. (deposition date: 2012-05-08, release date: 2012-05-30, Last modification date: 2023-09-13)
Primary citation	Holley, S.M.,Ahmed, A.H.,Srinivasan, J.,Murthy, S.E.,Weiland, G.A.,Oswald, R.E.,Nowak, L.M. The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation. Biochemistry, 51:4015-4027, 2012 Cited by PubMed: 22512472 DOI: 10.1021/bi3001837 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.286 Å)

Structure validation