4F31

Kainate bound to the D655A mutant of the ligand binding domain of GluA3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, D)	Glutamate receptor 3	polymer	258	28926.4	2	UniProt (P19492) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (rat)	GluR-3, AMPA-selective glutamate receptor 3, GluR-C, GluR-K3, Glutamate receptor ionotropic, AMPA 3, GluA3
2	C, F (B, D)	3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE	non-polymer		213.2	2	Chemie (KAI) PubChem (3816) PubChem (10255) PubChem (73345) PubChem (23616889) PubChem (45039619) PubChem (3083828) PubChem (5317452) PubChem (5318769) PubChem (6453379) PubChem (6604705) PubChem (10036135) PubChem (11095940) PubChem (6603893) PubChem (101994997) PubChem (135037246)
3	D, E, G, H (B, D)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
4	I, J (B, D)	water	water		18.0	252	Chemie (HOH)

Sequence modifications

B, D: 4 - 117 (UniProt: P19492)
B, D: 120 - 261 (UniProt: P19492)

PDB	External Database	Details
Gly 118	-	linker
Thr 119	-	linker
Ala 139	Asp 677	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	57852.8
Non-Polymers*	Number of molecules	6
	Total formula weight	688.1
All*	Total formula weight	58540.9

*Water molecules are not included.