3VRJ
 
 | | HLA-B*57:01-LTTKLTNTNI in complex with abacavir | | 分子名称: | 10-mer peptide, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | 著者 | Vivian, J.P, Illing, P.T, McCluskey, J, Rossjohn, J. | | 登録日 | 2012-04-11 | | 公開日 | 2012-05-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Immune self-reactivity triggered by drug-modified HLA-peptide repertoire
Nature, 486, 2012
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1JGD
 | | HLA-B*2709 bound to deca-peptide s10R | | 分子名称: | BETA-2-MICROGLOBULIN, GLYCEROL, HUMAN LYMPHOCYTE ANTIGEN HLA-B27, ... | | 著者 | Hillig, R.C, Huelsmeyer, M, Saenger, W, Volz, A, Uchanska-Ziegler, B, Ziegler, A. | | 登録日 | 2001-06-25 | | 公開日 | 2003-07-01 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Thermodynamic and structural analysis
of peptide- and allele-dependent properties
of two HLA-B27 subtypes exhibiting differential disease
association
J.Biol.Chem., 279, 2004
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4O2F
 | | A peptide complexed with HLA-B*3901 | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-39 alpha chain, ... | | 著者 | Sun, M, Liu, J, Qi, J, Tefsen, B, Shi, Y, Yan, J, Gao, G.F. | | 登録日 | 2013-12-17 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | | 主引用文献 | N alpha-terminal acetylation for T cell recognition: molecular basis of MHC class I-restricted n alpha-acetylpeptide presentation
J.Immunol., 192, 2014
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5IB1
 | | Crystal structure of HLA-B*27:05 complexed with the self-peptide pVIPR measured at 295 K | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-27 alpha chain, ... | | 著者 | Janke, R, Ballaschk, M, Schmieder, P, Uchanska-Ziegler, B, Ziegler, A, Loll, B. | | 登録日 | 2016-02-22 | | 公開日 | 2017-02-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype.
J.Biol.Chem., 2019
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5IB3
 | | Crystal structure of HLA-B*27:05 complexed with the self-peptide pVIPR and Copper | | 分子名称: | Beta-2-microglobulin, COPPER (II) ION, GLYCEROL, ... | | 著者 | Janke, R, Ballaschk, M, Schmieder, P, Uchanska-Ziegler, B, Ziegler, A, Loll, B. | | 登録日 | 2016-02-22 | | 公開日 | 2017-02-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype.
J.Biol.Chem., 2019
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4U1I
 | | HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes | | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GAG protein, ... | | 著者 | Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K. | | 登録日 | 2014-07-15 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
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3LV3
 | | Crystal structure of HLA-B*2705 complexed with a peptide derived from the human voltage-dependent calcium channel alpha1 subunit (residues 513-521) | | 分子名称: | 9-meric peptide from Voltage-dependent L-type calcium channel subunit alpha-1D, Beta-2-microglobulin, GLYCEROL, ... | | 著者 | Loll, B, Rueckert, C, Saenger, W, Uchanska-Ziegler, B, Ziegler, A. | | 登録日 | 2010-02-19 | | 公開日 | 2010-11-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Loss of recognition by cross-reactive T cells and its relation to a C-terminus-induced conformational reorientation of an HLA-B*2705-bound peptide.
Protein Sci., 20, 2011
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3VFT
 | | crystal structure of HLA B*3508LPEP-P6Ala, peptide mutant P6-ala | | 分子名称: | Beta-2-microglobulin, LPEP peptide from EBV, P6A, ... | | 著者 | Liu, Y.C, Rossjohn, J, Gras, S. | | 登録日 | 2012-01-10 | | 公開日 | 2012-02-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.947 Å) | | 主引用文献 | The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
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2YPK
 | | Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms | | 分子名称: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN, ... | | 著者 | Stewart-Jones, G.B, Simpson, P, Van Der Merwe, P.A, Easterbrook, P, Mcmichael, A.J, Rowland-Jones, S.L, Jones, E.Y, Gillespie, G.M. | | 登録日 | 2012-10-30 | | 公開日 | 2012-11-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural Features Underlying T-Cell Receptor Sensitivity to Concealed Mhc Class I Micropolymorphisms.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3HCV
 | | Crystal structure of HLA-B*2709 complexed with the double citrullinated vasoactive intestinal peptide type 1 receptor (VIPR) peptide (residues 400-408) | | 分子名称: | Beta-2-microglobulin, DOUBLE CITRULLINATED VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR, HLA class I histocompatibility antigen, ... | | 著者 | Beltrami, A, Gabdulkhakov, A, Rossmann, M, Ziegler, A, Uchanska-Ziegler, B, Saenger, W. | | 登録日 | 2009-05-06 | | 公開日 | 2009-06-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Citrullination-and mhc polymorphism-dependent conformational changes of
a self peptide
To be Published
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5IB4
 | | Crystal structure of HLA-B*27:05 complexed with the self-peptide pVIPR and Nickel | | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | 著者 | Janke, R, Ballaschk, M, Schmieder, P, Uchanska-Ziegler, B, Ziegler, A, Loll, B. | | 登録日 | 2016-02-22 | | 公開日 | 2017-02-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype.
J.Biol.Chem., 2019
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3KPL
 | | Crystal Structure of HLA B*4402 in complex with EEYLQAFTY a self peptide from the ABCD3 protein | | 分子名称: | Beta-2-microglobulin, EEYLQAFTY, self peptide from the ATP binding cassette protein ABCD3, ... | | 著者 | Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J. | | 登録日 | 2009-11-16 | | 公開日 | 2009-12-22 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
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7LGT
 | | HLA-B*07:02 in complex with 229E-derived coronavirus nucleocapsid peptide N75-83 | | 分子名称: | BROMIDE ION, Beta-2-microglobulin, CHLORIDE ION, ... | | 著者 | Gras, S, Szeto, C, Chatzileontiadou, D.S.M. | | 登録日 | 2021-01-21 | | 公開日 | 2021-04-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | CD8 + T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses.
Immunity, 54, 2021
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4O2E
 | | A peptide complexed with HLA-B*3901 | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-39 alpha chain, ... | | 著者 | Sun, M, Liu, J, Qi, J, Tefsen, B, Shi, Y, Yan, J, Gao, G.F. | | 登録日 | 2013-12-17 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | | 主引用文献 | N alpha-terminal acetylation for T cell recognition: molecular basis of MHC class I-restricted n alpha-acetylpeptide presentation
J.Immunol., 192, 2014
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3UPR
 | | HLA-B*57:01 complexed to pep-V and Abacavir | | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, HLA class I histocompatibility antigen, ... | | 著者 | Pompeu, Y.A, Ostrov, D.A. | | 登録日 | 2011-11-18 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | | 主引用文献 | Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire.
Proc.Natl.Acad.Sci.USA, 109, 2012
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5VWJ
 | | HLA-B*58:01 presenting LTVQVARVW | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-58 alpha chain, ... | | 著者 | Pymm, P, Rossjohn, J, Vivian, J.P. | | 登録日 | 2017-05-22 | | 公開日 | 2018-10-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.
Nat Commun, 9, 2018
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3WUW
 | | KIR3DL1 in complex with HLA-B*57:01.I80T | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | 著者 | Vivian, J.P, Rossjohn, J. | | 登録日 | 2014-05-06 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity
J.Immunol., 192, 2014
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3X14
 | | Crystal structure of HLA-B*0801.N80I.R82L.G83R | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ... | | 著者 | Vivian, J.P, Rossjohn, J. | | 登録日 | 2014-10-25 | | 公開日 | 2014-12-24 | | 最終更新日 | 2015-04-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope
J.Immunol., 194, 2015
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3LKR
 | | Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 2009 H1N1 swine origin strain | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... | | 著者 | Gras, S, Kedzierski, L, Valkenburg, S.A, Liu, Y.C, Denholm, J, Richards, M, Rimmelzwaan, G.F, Doherty, P.C, Turner, S.J, Rossjohn, J, Kedzierska, K. | | 登録日 | 2010-01-27 | | 公開日 | 2010-07-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3LKN
 | | Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 1918 strain | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... | | 著者 | Gras, S, Kedzierski, L, Valkenburg, S.A, Liu, Y.C, Denholm, J, Richards, M, Rimmelzwaan, G.F, Doherty, P.C, Turner, S.J, Rossjohn, J, Kedzierska, K. | | 登録日 | 2010-01-27 | | 公開日 | 2010-07-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses.
Proc.Natl.Acad.Sci.USA, 107, 2010
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5U98
 | | The crystal structure of a self-peptide complexed to Abacavir and HLA-B*57:01 | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ... | | 著者 | Ostrov, D.A, Bracey, A.W, Pompeu, Y.A, Jakoncic, J, Buus, S, Buus, A.S, Schutte, R.J. | | 登録日 | 2016-12-15 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Elements Recognized by Abacavir-Induced T Cells.
Int J Mol Sci, 18, 2017
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2AXG
 | | The Immunogenicity of a Viral Cytotoxic T Cell Epitope is controlled by its MHC-bound Conformation | | 分子名称: | 10-mer peptide from BZLF1 trans-activator protein, ACETIC ACID, Beta-2-microglobulin, ... | | 著者 | Tynan, F.E, Elhassen, D, Purcell, A.W, Burrows, J.M, Borg, N.A, Miles, J.J, Williamson, N.A, Green, K.J, Tellam, J, Kjer-Nielsen, L, McCluskey, J, Rossjohn, J, Burrows, S.R. | | 登録日 | 2005-09-05 | | 公開日 | 2005-11-29 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation
J.Exp.Med., 202, 2005
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2BVQ
 | | Structures of Three HIV-1 HLA-B5703-Peptide Complexes and Identification of Related HLAs Potentially Associated with Long-Term Non-Progression | | 分子名称: | BETA-2-MICROGLOBULIN, HIV-P24, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | | 著者 | Stewart-Jones, G.B, Gillespie, G, Overton, I.M, Kaul, R, Roche, P, Mcmichael, A.J, Rowland-Jones, S, Jones, E.Y. | | 登録日 | 2005-07-01 | | 公開日 | 2005-09-07 | | 最終更新日 | 2019-10-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of three HIV-1 HLA-B*5703-peptide complexes and identification of related HLAs potentially associated with long-term nonprogression.
J Immunol., 175, 2005
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5T6Z
 | | KIR3DL1 in complex with HLA-B*57:01-TW10 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Decapeptide: THR-SER-THR-LEU-GLN-GLU-GLN-ILE-GLY-TRP, ... | | 著者 | Pymm, P, Rossjohn, J, Vivian, J.P. | | 登録日 | 2016-09-02 | | 公開日 | 2017-03-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.
Nat. Struct. Mol. Biol., 24, 2017
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2BSS
 | | Crystal structures and KIR3DL1 recognition of three immunodominant viral peptides complexed to HLA-B2705 | | 分子名称: | BETA-2-MICROGLOBULIN, HIV PEPTIDE, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN B-27 ALPHA CHAIN | | 著者 | Stewart-Jones, G.B.E, Di Gleria, K, Kollnberger, S, Mcmichael, A.J, Jones, E.Y, Bowness, P. | | 登録日 | 2005-05-23 | | 公開日 | 2005-05-24 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structures and Kir3Dl1 Recognition of Three Immunodominant Viral Peptides Complexed to Hla-B2705
Eur.J.Immunol., 35, 2005
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