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PDB: 22 件
4YAA
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YopH W354Y Yersinia enterocolitica PTPase apo form
分子名称: ACETATE ION, SULFATE ION, Tyrosine-protein phosphatase YopH
著者Moise, G.E, Johnson, S.J, Hengge, A.C.
登録日2015-02-17
公開日2015-10-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Conservative Tryptophan Mutants of the Protein Tyrosine Phosphatase YopH Exhibit Impaired WPD-Loop Function and Crystallize with Divanadate Esters in Their Active Sites.
Biochemistry, 54, 2015
4ZN5
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YopH W354Y Yersinia enterocolitica PTPase bond with Divanadate glycerol ester in the active site
分子名称: ACETATE ION, Divanadate Glycerol ester, GLYCEROL, ...
著者Moise, G.E, Johnson, S.J, Hengge, A.C.
登録日2015-05-04
公開日2015-10-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Conservative Tryptophan Mutants of the Protein Tyrosine Phosphatase YopH Exhibit Impaired WPD-Loop Function and Crystallize with Divanadate Esters in Their Active Sites.
Biochemistry, 54, 2015
4ZI4
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YopH W354H Yersinia enterocolitica PTPase bond with Divanadate glycerol ester in the active site
分子名称: Divanadate Glycerol ester, Tyrosine-protein phosphatase YopH, VANADATE ION
著者Moise, G.E, Johnson, S.J, Hengge, A.C.
登録日2015-04-27
公開日2015-10-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.121 Å)
主引用文献Conservative Tryptophan Mutants of the Protein Tyrosine Phosphatase YopH Exhibit Impaired WPD-Loop Function and Crystallize with Divanadate Esters in Their Active Sites.
Biochemistry, 54, 2015
4Z6B
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YopH W354H Yersinia enterocolitica PTPase in the apo form
分子名称: ACETATE ION, GLYCEROL, Tyrosine-protein phosphatase YopH
著者Moise, G.E, Johnson, S.J, Hengge, A.C.
登録日2015-04-04
公開日2015-10-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Conservative Tryptophan Mutants of the Protein Tyrosine Phosphatase YopH Exhibit Impaired WPD-Loop Function and Crystallize with Divanadate Esters in Their Active Sites.
Biochemistry, 54, 2015
1LYV
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High-resolution structure of the catalytically inactive yersinia tyrosine phosphatase C403A mutant in complex with phosphate.
分子名称: CHLORIDE ION, PHOSPHATE ION, PROTEIN-TYROSINE PHOSPHATASE YOPH
著者Evdokimov, A.G, Waugh, D.S, Routzahn, K, Tropea, J, Cherry, S.
登録日2002-06-08
公開日2002-07-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.363 Å)
主引用文献High-resolution structure of the catalytically inactive yersinia tyrosine phosphatase C403A mutant in complex with phosphate.
To be Published
3F9B
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W354F Yersinia enterocolitica PTPase complexed with divanadate
分子名称: Divanadate ion, GLYCEROL, Tyrosine-protein phosphatase yopH, ...
著者Brandao, T.A.S, Robinson, H, Johnson, S.J, Hengge, A.C.
登録日2008-11-13
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Impaired acid catalysis by mutation of a protein loop hinge residue in a YopH mutant revealed by crystal structures.
J.Am.Chem.Soc., 131, 2009
3F99
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W354F Yersinia enterocolitica PTPase apo form
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase yopH
著者Brandao, T.A.S, Robinson, H, Johnson, S.J, Hengge, A.C.
登録日2008-11-13
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Impaired acid catalysis by mutation of a protein loop hinge residue in a YopH mutant revealed by crystal structures.
J.Am.Chem.Soc., 131, 2009
3F9A
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W354F Yersinia enterocolitica PTPase complexed with tungstate
分子名称: TUNGSTATE(VI)ION, Tyrosine-protein phosphatase yopH
著者Brandao, T.A.S, Robinson, H, Johnson, S.J, Hengge, A.C.
登録日2008-11-13
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Impaired acid catalysis by mutation of a protein loop hinge residue in a YopH mutant revealed by crystal structures.
J.Am.Chem.Soc., 131, 2009
6XFT
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Crystal Structure of the Cys-NO Modified YopH Tyrosine Phosphatase
分子名称: Tyrosine-protein phosphatase YopH
著者Fernandes, R, Pereira, H.M, Thiemann, O, Terenzi, H.
登録日2020-06-16
公開日2021-06-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal structure of the Cys-NO modified YopH tyrosine phosphatase.
Biochim Biophys Acta Proteins Proteom, 1870, 2022
3U96
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Crystal Structure of YopHQ357F(Catalytic Domain, Residues 163-468) in complex with pNCS
分子名称: N,4-DIHYDROXY-N-OXO-3-(SULFOOXY)BENZENAMINIUM, SULFATE ION, Tyrosine-protein phosphatase yopH
著者Ho, M.C, Ke, S.
登録日2011-10-17
公開日2012-08-29
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Investigation of catalytic loop structure, dynamics, and function relationship of Yersinia protein tyrosine phosphatase by temperature-jump relaxation spectroscopy and X-ray structural determination.
J.Phys.Chem.B, 116, 2012
4GF3
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Structure of a SycH-YopH Chaperone-Effector Complex
分子名称: Putative yopH targeting protein, Tyrosine-protein phosphatase yopH
著者Stebbins, C.E, Vujanac, M.
登録日2012-08-02
公開日2013-03-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Context-dependent protein folding of a virulence peptide in the bacterial and host environments: structure of an SycH-YopH chaperone-effector complex.
Acta Crystallogr.,Sect.D, 69, 2013
1PA9
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Yersinia Protein-Tyrosine Phosphatase complexed with pNCS (Yop51,Pasteurella X,Ptpase,Yop51delta162) (Catalytic Domain, Residues 163-468) Mutant With Cys 235 Replaced By Arg (C235r)
分子名称: N,4-DIHYDROXY-N-OXO-3-(SULFOOXY)BENZENAMINIUM, Protein-tyrosine phosphatase yopH
著者Sun, J.P, Wu, L, Fedorov, A.A, Almo, S.C, Zhang, Z.Y.
登録日2003-05-13
公開日2003-11-04
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the Yersinia protein-tyrosine phosphatase YopH complexed with a specific small molecule inhibitor
J.BIOL.CHEM., 278, 2003
3BLU
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BU of 3blu by Molmil
crystal structure YopH complexed with inhibitor PVS
分子名称: (ethenylsulfonyl)benzene, Tyrosine-protein phosphatase yopH
著者Liu, S, Zhang, Z.-Y.
登録日2007-12-11
公開日2008-10-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Aryl vinyl sulfonates and sulfones as active site-directed and mechanism-based probes for protein tyrosine phosphatases
J.Am.Chem.Soc., 130, 2008
2I42
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Crystal structure of Yersinia protein tyrosine phosphatase complexed with vanadate, a transition state analogue
分子名称: Tyrosine-protein phosphatase, VANADATE ION
著者Vijayalakshmi, J, Saper, M.A.
登録日2006-08-21
公開日2006-09-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Yersinia protein tyrosine phosphatase complexed with vanadate, a transition state analogue
To be Published
3BLT
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Crystal structures of YopH complexed with PVSN and PVS, inhibitors of YopH which co-valent bind to Cys of active site
分子名称: Tyrosine-protein phosphatase yopH, phenyl ethenesulfonate
著者Liu, S, Zhang, Z.-Y.
登録日2007-12-11
公開日2009-02-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Aryl vinyl sulfonates and sulfones as active site-directed and mechanism-based probes for protein tyrosine phosphatases.
J.Am.Chem.Soc., 130, 2008
1YTN
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BU of 1ytn by Molmil
HYDROLASE
分子名称: NITRATE ION, YERSINIA PROTEIN TYROSINE PHOSPHATASE
著者Yuvaniyama, C, Fauman, E.B, Saper, M.A.
登録日1996-05-01
公開日1996-11-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The X-ray crystal structures of Yersinia tyrosine phosphatase with bound tungstate and nitrate. Mechanistic implications.
J.Biol.Chem., 271, 1996
1YTW
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BU of 1ytw by Molmil
YERSINIA PTPASE COMPLEXED WITH TUNGSTATE
分子名称: SULFATE ION, TUNGSTATE(VI)ION, YERSINIA PROTEIN TYROSINE PHOSPHATASE
著者Fauman, E.B, Schubert, H.L, Saper, M.A.
登録日1996-05-01
公開日1996-11-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The X-ray crystal structures of Yersinia tyrosine phosphatase with bound tungstate and nitrate. Mechanistic implications.
J.Biol.Chem., 271, 1996
1XXV
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Yersinia YopH (residues 163-468) binds phosphonodifluoromethyl-Phe containing hexapeptide at two sites
分子名称: Epidermal growth factor receptor derived peptide, Protein-tyrosine phosphatase yopH
著者Ivanov, M.I, Stuckey, J.A, Schubert, H.L, Saper, M.A, Bliska, J.B.
登録日2004-11-08
公開日2005-03-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Two substrate-targeting sites in the Yersinia protein tyrosine phosphatase co-operate to promote bacterial virulence
Mol.Microbiol., 55, 2005
1YTS
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A LIGAND-INDUCED CONFORMATIONAL CHANGE IN THE YERSINIA PROTEIN TYROSINE PHOSPHATASE
分子名称: SULFATE ION, YERSINIA PROTEIN TYROSINE PHOSPHATASE
著者Schubert, H.L, Stuckey, J.A, Fauman, E.B, Dixon, J.E, Saper, M.A.
登録日1995-04-07
公開日1995-07-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A ligand-induced conformational change in the Yersinia protein tyrosine phosphatase.
Protein Sci., 4, 1995
1YPT
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CRYSTAL STRUCTURE OF YERSINIA PROTEIN TYROSINE PHOSPHATASE AT 2.5 ANGSTROMS AND THE COMPLEX WITH TUNGSTATE
分子名称: PROTEIN-TYROSINE PHOSPHATASE YERSINIA (CATALYTIC DOMAIN)
著者Stuckey, J.A, Schubert, H.L, Fauman, E.B, Zhang, Z.-Y, Dixon, J.E, Saper, M.A.
登録日1994-09-16
公開日1994-12-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 A and the complex with tungstate.
Nature, 370, 1994
3BM8
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crystal structure of YopH mutant D356A complexed with irreversible inhibitor PVSN
分子名称: Tyrosine-protein phosphatase yopH, phenyl ethenesulfonate
著者Zhang, Z.Y, Liu, S.J.
登録日2007-12-12
公開日2008-06-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Aryl vinyl sulfonates and sulfones as active site-directed and mechanism-based probes for protein tyrosine phosphatases.
J.Am.Chem.Soc., 130, 2008
1XXP
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Yersinia YopH (residues 163-468) C403S binds phosphotyrosyl peptide at two sites
分子名称: Hexapeptide ASP-ALA-ASP-GLU-PTR-CLE, Protein-tyrosine phosphatase yopH
著者Ivanov, M.I, Stuckey, J.A, Schubert, H.L, Saper, M.A, Bliska, J.B.
登録日2004-11-07
公開日2005-03-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Two substrate-targeting sites in the Yersinia protein tyrosine phosphatase co-operate to promote bacterial virulence
Mol.Microbiol., 55, 2005

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