3BM8
crystal structure of YopH mutant D356A complexed with irreversible inhibitor PVSN
Summary for 3BM8
| Entry DOI | 10.2210/pdb3bm8/pdb |
| Descriptor | Tyrosine-protein phosphatase yopH, phenyl ethenesulfonate (3 entities in total) |
| Functional Keywords | co-valent binding, pvsn, binding selectivity, binding affinity, hydrolase, membrane, outer membrane, plasmid, protein phosphatase, secreted, virulence |
| Biological source | Yersinia enterocolitica |
| Cellular location | Secreted: P15273 |
| Total number of polymer chains | 1 |
| Total formula weight | 33562.89 |
| Authors | Zhang, Z.Y.,Liu, S.J. (deposition date: 2007-12-12, release date: 2008-06-17, Last modification date: 2023-08-30) |
| Primary citation | Liu, S.,Zhou, B.,Yang, H.,He, Y.,Jiang, Z.X.,Kumar, S.,Wu, L.,Zhang, Z.Y. Aryl vinyl sulfonates and sulfones as active site-directed and mechanism-based probes for protein tyrosine phosphatases. J.Am.Chem.Soc., 130:8251-8260, 2008 Cited by PubMed: 18528979DOI: 10.1021/ja711125p PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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